Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Isidore Wodinsky"'
Publikováno v:
International Journal of Cancer. 21:482-489
Surgical-adjuvant chemotherapy studies were done with BDF1 mice bearing Lewis Lung (LL) carcinoma implanted intramuscularly (IM). Ten days (D10) after implantation, the tumor-bearing leg was surgically amputated, and intraperitoneal (IP) drug treatme
Publikováno v:
Cryobiology. 15:636-642
Freezing of 34 murine neoplasms for 9 to 12 years in liquid nitrogen showed that (1) all the tumor lines were viable, although the mean survival time (MST) of 16 of these lines was prolonged when the neoplasms were injected directly from the frozen a
Publikováno v:
Advances in Enzyme Regulation. 19:309-333
Pyrazofurin (PF), following anabolism to the 5′-monophosphate by adenosine kinase, is a potent inhibition of protidine 5′-phosphate decarboxylase. Although PF has little activity in experimental or human tumors, this antibiotic can be employed to
Publikováno v:
The Journal of Experimental Medicine
A survey of inbred strains of mice was made to determine whether the phenomenon of dermal hemorrhagic necrosis, as described in rabbits by Shwartzman, could be elicited in mice by bacterial polysaccharide preparations of demonstrated activity in rabb
Publikováno v:
Cryobiology. 1:217-226
Fifty-five neoplasms of mice, rats, and hamsters and of human cell origin have been stored at liquid nitrogen temperature for periods up to 1 year after slow freezing with a Canalco controlled temperature unit. Fifty-three of these tumors have remain
Autor:
David Kessel, Isidore Wodinsky
Publikováno v:
Biochemical Pharmacology. 17:161-164
Publikováno v:
Cryobiology. 4:333-336
Summary The spleen colony assay showed that the percentage of viable L1210 cells frozen to −15°C and thawed was similar to that for nonfrozen leukemic cells as estimated by colonyforming units (CFU). At temperatures between −15 and −60°C, the
Publikováno v:
Biochemical Pharmacology. 17:305-313
Suramin forms water-insoluble complexes with 4′,4″- bis (1,4,5,6-tetrahydro-2-pyrimidinyl)terephthalanilide (NSC 57153). The mole ratio of Suramin-drug for maximum complex formation is 0·3:1 . Excess Suramin dissolves this precipitate whereas ex
Publikováno v:
Biochemical Pharmacology. 18:1229-1234
The accumulation of two alkylating agents by murine leukemia cells in vitro was studied. Nitrogen mustard (HN 2 ) and busulfan rapidly penetrated cells; cell-medium drug distribution ratios of one were established within 3 min at 0° over a wide rang
Publikováno v:
International journal of radiation oncology, biology, physics. 4(1-2)
The methodologies and objectives involved in the search for new radiation potentiators, as in the search for new drugs and combinations of drugs, are aimed at obtaining enhanced therapeutic effectiveness in the treatment of the tumorous host. A disti