Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Isidore, Rigoutsos"'
Autor:
Tess Cherlin, Yi Jing, Siddhartha Shah, Anne Kennedy, Aristeidis G. Telonis, Venetia Pliatsika, Haley Wilson, Lily Thompson, Panagiotis I. Vlantis, Phillipe Loher, Benjamin Leiby, Isidore Rigoutsos
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background MicroRNA isoforms (isomiRs), tRNA-derived fragments (tRFs), and rRNA-derived fragments (rRFs) represent most of the small non-coding RNAs (sncRNAs) found in cells. Members of these three classes modulate messenger RNA (mRNA) and p
Externí odkaz:
https://doaj.org/article/2ee294a745a84975b4af7d3a1471e9da
Autor:
Alexis M Zebrowski, Phillipe Loher, David G Buckler, Isidore Rigoutsos, Brendan G Carr, Douglas J Wiebe
Publikováno v:
PLOS Digital Health, Vol 2, Iss 6, p e0000263 (2023)
Trauma centers use registry data to benchmark performance using a standardized risk adjustment model. Our objective was to utilize national claims to develop a risk adjustment model applicable across all hospitals, regardless of designation or regist
Externí odkaz:
https://doaj.org/article/fef0d966ddd24c2fbd00eba7c352630a
Autor:
Robert Brian Akins, Kayleigh Ostberg, Tess Cherlin, Nikolas J. Tsiouplis, Phillipe Loher, Isidore Rigoutsos
Publikováno v:
Non-Coding RNA, Vol 9, Iss 6, p 69 (2023)
Transfer RNA-derived fragments (tRFs) are noncoding RNAs that arise from either mature transfer RNAs (tRNAs) or their precursors. One important category of tRFs comprises the tRNA halves, which are generated through cleavage at the anticodon. A given
Externí odkaz:
https://doaj.org/article/3a3b97d7c5cd460a80eaf3d8408aea0f
Autor:
Nestoras Karathanasis, Daniel Hwang, Vibol Heng, Rimal Abhimannyu, Phillip Slogoff-Sevilla, Gina Buchel, Victoria Frisbie, Peiyao Li, Dafni Kryoneriti, Isidore Rigoutsos
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010615 (2022)
The "replication crisis" is a methodological problem in which many scientific research findings have been difficult or impossible to replicate. Because the reproducibility of empirical results is an essential aspect of the scientific method, such fai
Externí odkaz:
https://doaj.org/article/40248b4e44854a57ad5531c5516e8273
Autor:
Megumi Shigematsu, Takuya Kawamura, Keisuke Morichika, Natsuko Izumi, Takashi Kiuchi, Shozo Honda, Venetia Pliatsika, Ryuma Matsubara, Isidore Rigoutsos, Susumu Katsuma, Yukihide Tomari, Yohei Kirino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Mature piRNAs are produced from long single-stranded precursor RNAs. Here the authors show that RNase κ generates 2′,3′-cyclic phosphate-containing piRNA precursors and promotes piRNA production.
Externí odkaz:
https://doaj.org/article/939dadb0138143918c8127b14eb6589f
Autor:
Emi Dika, Elisabetta Broseghini, Elisa Porcellini, Martina Lambertini, Mattia Riefolo, Giorgio Durante, Phillipe Loher, Roberta Roncarati, Cristian Bassi, Cosimo Misciali, Massimo Negrini, Isidore Rigoutsos, Eric Londin, Annalisa Patrizi, Manuela Ferracin
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-15 (2021)
Abstract Malignant cutaneous melanoma (CM) is a potentially lethal form of skin cancer whose worldwide incidence has been constantly increasing over the past decades. During their lifetime, about 8% of CM patients will develop multiple primary melano
Externí odkaz:
https://doaj.org/article/01c29143bc58464e9736215a00281a9c
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-19 (2021)
Abstract Background Extensive molecular differences exist between proliferative and differentiated cells. Here, we conduct a meta-analysis of publicly available transcriptomic datasets from preimplantation and differentiation stages examining the arc
Externí odkaz:
https://doaj.org/article/12b99bded7d44fb596a9f6fb07aa6946
Autor:
Angelica Giuliani, Eric Londin, Manuela Ferracin, Emanuela Mensà, Francesco Prattichizzo, Deborah Ramini, Fiorella Marcheselli, Rina Recchioni, Maria Rita Rippo, Massimiliano Bonafè, Isidore Rigoutsos, Fabiola Olivieri, Jacopo Sabbatinelli
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis of selected microRNAs (miRNAs) was recently suggested. MicroRNA isoforms (isomiRs)
Externí odkaz:
https://doaj.org/article/9db56585c5b24fc0af64d8a7a31bcb9d
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background The advent of next generation sequencing (NGS) has allowed the discovery of short and long non-coding RNAs (ncRNAs) in an unbiased manner using reverse genetics approaches, enabling the discovery of multiple categories of ncRNAs a
Externí odkaz:
https://doaj.org/article/37fd55a885c74529ae7c973dfa2b79c6
Autor:
Seema Bhatlekar, Shancy Jacob, Emilia Tugolukova, Bhanu K. Manne, Yasuhiro Kosaka, Phillipe Loher, Ryan M. O’Connell, Vicente Planelles, Matthew T. Rondina, Isidore Rigoutsos, Paul F. Bray
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/776c2e22372247eb9d8d925e4c500b13