Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Ishwar S. Parhar"'
Autor:
Khaled Benchoula, Christopher J. Serpell, Ahmed Mediani, Abdulaziz Albogami, Norazlan Mohmad Misnan, Nor Hadiani Ismail, Ishwar S. Parhar, Satoshi Ogawa, Wong Eng Hwa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Zebrafish have been utilized for many years as a model animal for pharmacological studies on diabetes and obesity. High-fat diet (HFD), streptozotocin and alloxan injection, and glucose immersion have all been used to induce diabetes and obe
Externí odkaz:
https://doaj.org/article/dec096cf111549cf91b3337c3e942194
Autor:
Mei Fong Ng, Juliana Da Silva Viana, Pei Jean Tan, Denver D. Britto, Sy Bing Choi, Sakurako Kobayashi, Norazwana Samat, Dedrick Soon Seng Song, Satoshi Ogawa, Ishwar S. Parhar, Jonathan W. Astin, Benjamin M. Hogan, Vyomesh Patel, Kazuhide S. Okuda
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 108 (2024)
Tumour-associated angiogenesis play key roles in tumour growth and cancer metastasis. Consequently, several anti-angiogenic drugs such as sunitinib and axitinib have been approved for use as anti-cancer therapies. However, the majority of these drugs
Externí odkaz:
https://doaj.org/article/5fb5f72b7457456c83d2000c4f68f22a
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Spexin (SPX) and galanin (GAL) are two neuropeptides that are phylogenetically related and have descended from a common ancestral gene. Considerable attention has been given to these two multifunctional neuropeptides because they share GAL receptors
Externí odkaz:
https://doaj.org/article/e5ccb21c65db44199a439f7f2fdc87a6
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Spexin (SPX), a neuropeptide evolutionarily conserved from fish to mammals, is widely distributed in the brain and peripheral tissues and associated with various physiological functions. Recently SPX has been suggested to be involved in neur
Externí odkaz:
https://doaj.org/article/e9f6168d62e64d929d96e7251f5012c8
Autor:
Satoshi Ogawa, Ishwar S. Parhar
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2022)
Social behaviors such as mating, parenting, fighting, and avoiding are essential functions as a communication tool in social animals, and are critical for the survival of individuals and species. Social behaviors are controlled by a complex circuitry
Externí odkaz:
https://doaj.org/article/620f2f08954b4c0da38bf3da516b05b7
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Substance P (SP) and neurokinin A (NKA), encoded by TAC1/Tac1 gene are members of the tachykinin family, which exert their neuromodulatory roles in vertebrate reproduction. In mammals, SP and NKA have been shown to regulate gonadotropin-releasing hor
Externí odkaz:
https://doaj.org/article/05107faa28c94da5a8b061f19a4e45d9
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2021)
Repressor element-1 silencing transcription factor (REST) is highly expressed in the dorsal raphe where serotonin (5-hydroxytryptamine, 5-HT) neurons are located. REST works as a transcription factor for the 5-HT receptor and tryptophan hydroxylase t
Externí odkaz:
https://doaj.org/article/973c3d225af5422aac6aa729dcabdb76
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Morphine is a potent analgesic opiate commonly used in treating pain, and it is also a substance of abuse and highly addictive. Hence, it is vital to discover the action sites of morphine in the brain to increase its efficacy of treatment. In the pre
Externí odkaz:
https://doaj.org/article/211fed25c73a4d13b732313006d9b28b
Publikováno v:
Neurosignals, Vol 26, Iss 1, Pp 31-42 (2018)
Beta-catenin is a protein with dual functions in the cell, playing a role in both adhesion between cells as well as gene transcription via the canonical Wnt signalling pathway. In the canonical Wnt signalling pathway, beta-catenin again plays multipl
Externí odkaz:
https://doaj.org/article/c45e63a5e1ce4912a2e60156585b0bb4
Autor:
Preetha Rajendiran, Faizul Jaafar, Sonika Kar, Chenichery Sudhakumari, Balasubramanian Senthilkumaran, Ishwar S. Parhar
Publikováno v:
Biology, Vol 10, Iss 10, p 973 (2021)
The fish reproductive system is a complex biological system. Nonetheless, reproductive organ development is conserved, which starts with sex determination and then sex differentiation. The sex of a teleost is determined and differentiated from bipote
Externí odkaz:
https://doaj.org/article/f54f5227ceef4fc28ee5b84aa30936cb