Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Ishwar S Parhar"'
Autor:
Kah Yee Tai, KokSheik Wong, Farhang Aghakhanian, Ishwar S Parhar, Jasbir Dhaliwal, Qasim Ayub
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Publicly available genome data provides valuable information on the genetic variation patterns across different modern human populations. Neuropeptide genes are crucial to the nervous, immune, endocrine system, and physiological h
Externí odkaz:
https://doaj.org/article/ab7708bfcac943658470b7f5654c9cc3
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Kisspeptin, a newly discovered neuropeptide regulates gonadotropin-releasing hormone (GnRH). Kisspeptins are a large RF-amide family of peptides. The kisspeptin coded by kiss1 gene is a 145-amino acid- protein that is cleaved to C-terminal peptide ki
Externí odkaz:
https://doaj.org/article/609e2b1510fa473b936fb0306755ef2b
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165535 (2016)
Non-rod non-cone photopigments in the eyes and the brain can directly mediate non-visual functions of light in non-mammals. This was supported by our recent findings on vertebrate ancient long (VAL)-opsin photopigments encoded by the val-opsinA (valo
Externí odkaz:
https://doaj.org/article/8ee968219b104f98ac671b2acbad2595
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Social isolation in early life deregulates the serotonergic system of the brain, compromising reproductive function. Gonadotropin-inhibitory hormone (GnIH) neurons in the dorsomedial hypothalamic nucleus are critical to the inhibitory regulation of g
Externí odkaz:
https://doaj.org/article/a7622ca58f354ab68d17d38d4027683b
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
Sexual dysfunction and cognitive deficits are markers of the ageing process. Mammalian sirtuins (SIRT), encoded by sirt 1-7 genes, are known as ageing molecules which are sensitive to serotonin (5-hydroxytryptamine, 5-HT). Whether the 5-HT system reg
Externí odkaz:
https://doaj.org/article/a43060d38d424b30a2fe7334e70a3549
Publikováno v:
Frontiers in Endocrinology, Vol 5 (2014)
Energy balance plays an important role in the control of reproduction. However, the cellular and molecular mechanisms connecting the two systems are not well understood especially in teleosts. The hypothalamus plays a crucial role in the regulation o
Externí odkaz:
https://doaj.org/article/9447413a876b41d3a71e119a4a6c4760
Autor:
Khaled Benchoula, Christopher J. Serpell, Ahmed Mediani, Abdulaziz Albogami, Norazlan Mohmad Misnan, Nor Hadiani Ismail, Ishwar S. Parhar, Satoshi Ogawa, Wong Eng Hwa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Zebrafish have been utilized for many years as a model animal for pharmacological studies on diabetes and obesity. High-fat diet (HFD), streptozotocin and alloxan injection, and glucose immersion have all been used to induce diabetes and obe
Externí odkaz:
https://doaj.org/article/dec096cf111549cf91b3337c3e942194
Publikováno v:
Frontiers in Endocrinology, Vol 4 (2013)
Guanine nucleotide binding protein (G-protein)-coupled receptors (GPCRs) are eukaryotic transmembrane proteins found in all living organisms. Their versatility and roles in several physiological processes make them the single largest family of drug t
Externí odkaz:
https://doaj.org/article/cfa5790c6c1042e7b26bb7534149fa19
Autor:
Mei Fong Ng, Juliana Da Silva Viana, Pei Jean Tan, Denver D. Britto, Sy Bing Choi, Sakurako Kobayashi, Norazwana Samat, Dedrick Soon Seng Song, Satoshi Ogawa, Ishwar S. Parhar, Jonathan W. Astin, Benjamin M. Hogan, Vyomesh Patel, Kazuhide S. Okuda
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 108 (2024)
Tumour-associated angiogenesis play key roles in tumour growth and cancer metastasis. Consequently, several anti-angiogenic drugs such as sunitinib and axitinib have been approved for use as anti-cancer therapies. However, the majority of these drugs
Externí odkaz:
https://doaj.org/article/5fb5f72b7457456c83d2000c4f68f22a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4088 (2023)
Several theories have been proposed to explain the mechanisms of substance use in schizophrenia. Brain neurons pose a potential to provide novel insights into the association between opioid addiction, withdrawal, and schizophrenia. Thus, we exposed z
Externí odkaz:
https://doaj.org/article/376e7884541b4d1db7da16948ba06756