Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies.

Autor: Stegmann JD; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, 53127, Germany. jil.stegmann@uni-bonn.de.; Institute of Anatomy and Cell Biology, Medical Faculty, University of Bonn, Bonn, 53115, Germany. jil.stegmann@uni-bonn.de., Kalanithy JC; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, 53127, Germany.; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Dworschak GC; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, 53127, Germany.; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany.; Department of Neuropediatrics, University Hospital Bonn, Bonn, 53127, Germany., Ishorst N; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, 53127, Germany.; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Mingardo E; Institute of Anatomy and Cell Biology, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Lopes FM; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK., Ho YM; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK., Grote P; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596, Frankfurt am Main, Germany., Lindenberg TT; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Yilmaz Ö; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Channab K; Institute of Anatomy and Cell Biology, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Seltzsam S; Division of Nephrology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Shril S; Division of Nephrology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Hildebrandt F; Division of Nephrology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Boschann F; Institute of Medical Genetics and Human Genetics, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Heinen A; Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Jolly A; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA., Myers K; Center for Cardiovascular Research, Nationwide Children's Hospital, Department of Pediatrics, Ohio State University, Columbus, OH, USA., McBride K; Center for Cardiovascular Research, Nationwide Children's Hospital, Department of Pediatrics, Ohio State University, Columbus, OH, USA., Bekheirnia MR; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Pediatrics, Renal Service, Texas Children's Hospital, Houston, TX, 77030, USA., Bekheirnia N; Department of Pediatrics, Renal Service, Texas Children's Hospital, Houston, TX, 77030, USA.; Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA., Scala M; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16132, Genoa, Italy.; U.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147, Genoa, Italy., Morleo M; Medical Genetics, Department of Precision Medicine, Università degli Studi della Campania 'Luigi Vanvitelli', via Luigi De Crecchio 7, 80138, Naples, Italy.; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Nigro V; Medical Genetics, Department of Precision Medicine, Università degli Studi della Campania 'Luigi Vanvitelli', via Luigi De Crecchio 7, 80138, Naples, Italy.; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Torella A; Medical Genetics, Department of Precision Medicine, Università degli Studi della Campania 'Luigi Vanvitelli', via Luigi De Crecchio 7, 80138, Naples, Italy.; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Pinelli M; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy.; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, Naples, Italy., Capra V; Genomics and Clinical Genetics, IRCCS Gaslini, Genoa, Italy., Accogli A; Division of Medical Genetics, Department of Specialized Medicine, McGill University, Montreal, QC, Canada.; Department of Human Genetics, McGill University, Montreal, QC, Canada., Maitz S; Medical Genetics Service, Oncology Department of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland., Spano A; MBBM Foundation, Monza, Italy., Olson RJ; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA., Klee EW; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Clinical Genomics, Mayo Clinic, Rochester, MN, USA.; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Lanpher BC; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Clinical Genomics, Mayo Clinic, Rochester, MN, USA., Jang SS; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea., Chae JH; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Genomics Medicine, Rare Disease Center, Seoul National University Hospital, Seoul, Republic of Korea., Steinbauer P; Division of Neonatology, Pediatric Intensive Care and Neuropediatrics, Comprehensive Center for Pediatrics, Medical University of Vienna, Vienna, Austria., Rieder D; Division of Bioinformatics, Medical University of Innsbruck, 6020, Innsbruck, Austria., Janecke AR; Department of Pediatrics I, Medical University of Innsbruck, 6020, Innsbruck, Austria.; Division of Human Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria., Vodopiutz J; Department of Pediatrics and Adolescent Medicine, Division of Pediatric Pulmonology, Allergology and Endocrinology, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090, Vienna, Austria., Vogel I; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., Blechingberg J; Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark., Cohen JL; Division of Medical Genetics, Department of Pediatrics, Duke University, Durham, NC, USA., Riley K; Department of Pediatrics, Duke University Medical Center, Durham, NC, USA., Klee V; Pediatric Neurology, Riley Hospital for Children Indiana University Health, Indianapolis, IN, USA., Walsh LE; Pediatric Neurology, Riley Hospital for Children Indiana University Health, Indianapolis, IN, USA., Begemann M; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany., Elbracht M; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany., Eggermann T; Institute for Human Genetics and Genomic Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany., Stoppe A; Division of Neuropediatrics and Social Pediatrics, Department of Pediatrics, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany., Stuurman K; Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands., van Slegtenhorst M; Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Barakat TS; Department of Clinical Genetics, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Mulhern MS; Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Department of Pathology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Sands TT; Division of Child Neurology, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.; Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, NY, USA.; Institute for Genomic Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA., Cytrynbaum C; Department of Genetic Counselling, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A1, Canada., Weksberg R; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A1, Canada.; Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Isidori F; U.O. Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Pippucci T; U.O. Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Severi G; U.O. Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Montanari F; U.O. Genetica Medica, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Kruer MC; Pediatric Movement Disorders Program, Division of Pediatric Neurology, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, AZ, USA.; Departments of Child Health, Neurology, and Cellular & Molecular Medicine, and Program in Genetics, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA., Bakhtiari S; Pediatric Movement Disorders Program, Division of Pediatric Neurology, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, AZ, USA.; Departments of Child Health, Neurology, and Cellular & Molecular Medicine, and Program in Genetics, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA., Darvish H; Neuroscience Research Center, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran., Reutter H; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, 53127, Germany.; Division Neonatology and Pediatric Intensive Care, Department of Pediatric and Adolescent Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany.; Institute of Human Genetics, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany., Hagelueken G; Institute of Structural Biology, University Hospital Bonn, University of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany., Geyer M; Institute of Structural Biology, University Hospital Bonn, University of Bonn, Venusberg-Campus 1, 53127, Bonn, Germany., Woolf AS; Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK.; Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Posey JE; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA., Lupski JR; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, 77030, USA.; Texas Children's Hospital, Houston, TX, 77030, USA., Odermatt B; Institute of Anatomy and Cell Biology, Medical Faculty, University of Bonn, Bonn, 53115, Germany.; Institute of Neuroanatomy, Medical Faculty, University of Bonn, Bonn, 53115, Germany., Hilger AC; Department of Pediatric and Adolescent Medicine, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, 91054, Germany. alina.hilger@uk-erlangen.de.; Research Center On Rare Kidney Diseases (RECORD), University Hospital Erlangen, 91054, Erlangen, Germany. alina.hilger@uk-erlangen.de.

Publikováno v: NPJ genomic medicine [NPJ Genom Med] 2024 Mar 01; Vol. 9 (1), pp. 18. Date of Electronic Publication: 2024 Mar 01.

MiRNA-149 as a Candidate for Facial Clefting and Neural Crest Cell Migration.

Autor: Stüssel, L.G., Hollstein, R., Laugsch, M., Hochfeld, L.M., Welzenbach, J., Schröder, J., Thieme, F., Ishorst, N., Romero, R. Olmos, Weinhold, L., Hess, T., Gehlen, J., Mostowska, A., Heilmann-Heimbach, S., Mangold, E., Rada-Iglesias, A., Knapp, M., Schaaf, C.P., Ludwig, K.U.

Publikováno v: Journal of Dental Research; Mar2022, Vol. 101 Issue 3, p323-330, 8p, 1 Chart, 2 Graphs

Identification of de novo variants in nonsyndromic cleft lip with/without cleft palate patients with low polygenic risk scores.

Autor: Ishorst N; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Henschel L; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Thieme F; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Drichel D; Cologne Center for Genomics, University of Cologne, Cologne, Germany., Sivalingam S; Core Unit for Bioinformatic Analysis, Medical Faculty, University of Bonn, Bonn, Germany.; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Mehrem SL; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Fechtner AC; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Fazaal J; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Welzenbach J; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Heimbach A; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Maj C; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Borisov O; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hausen J; Core Unit for Bioinformatic Analysis, Medical Faculty, University of Bonn, Bonn, Germany.; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Raff R; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hoischen A; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Dixon M; Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK., Rada-Iglesias A; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), CSIC/University of Cantabria, Santander, Spain., Bartusel M; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Rojas-Martinez A; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Mexico.; Centro de Investigacion y Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico., Aldhorae K; Department of Orthodontics, College of Dentistry, Thamar University, Thamar, Yemen.; Department of Orthodontics, College of Dentistry, University of Ibn al-Nafis for Medical Sciences, Sanaa, Yemen., Braumann B; Faculty of Medicine and University Hospital Cologne, Department of Orthodontics, University of Cologne, Cologne, Germany., Kruse T; Faculty of Medicine and University Hospital Cologne, Department of Orthodontics, University of Cologne, Cologne, Germany., Kirschneck C; Department of Orthodontics, University of Regensburg, Regensburg, Germany., Spanier G; Department of Cranio-Maxillofacial Surgery, University Hospital Regensburg, Regensburg, Germany., Reutter H; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.; Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Erlangen, Germany., Nowak S; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Gölz L; Department of Orthodontics, University of Erlangen-Nürnberg, Erlangen, Germany.; Department of Orthodontics, University of Bonn, Bonn, Germany., Knapp M; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Buness A; Core Unit for Bioinformatic Analysis, Medical Faculty, University of Bonn, Bonn, Germany.; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.; Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Krawitz P; Institute for Genomic Statistics and Bioinformatics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Nothnagel M; Cologne Center for Genomics, University of Cologne, Cologne, Germany.; University Hospital Cologne, Cologne, Germany., Becker T; Institute of Community Medicine, University of Greifswald, Greifswald, Germany., Ludwig KU; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Mangold E; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.

Publikováno v: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2023 Mar; Vol. 11 (3), pp. e2109. Date of Electronic Publication: 2022 Dec 05.

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Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding.

Autor: Ludwig KU; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Schmithausen RM; Institute of Hygiene and Public Health, University of Bonn and University Hospital Bonn, Bonn, Germany., Li D; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Jacobs ML; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany., Hollstein R; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Blumenstock K; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany., Liebing J; Institute of Experimental Oncology, University of Bonn and University Hospital Bonn, Bonn, Germany., Słabicki M; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany., Ben-Shmuel A; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Israeli O; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness Ziona, Israel., Weiss S; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Ebert TS; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany., Paran N; Department of Infectious Diseases, Israel Institute for Biological Research, Ness Ziona, Israel., Rüdiger W; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany., Wilbring G; Institute of Hygiene and Public Health, University of Bonn and University Hospital Bonn, Bonn, Germany., Feldman D; Department of Biochemistry and Institute for Protein Design, University of Washington, Seattle, WA, USA., Lippke B; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Ishorst N; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany.; Institute of Anatomy, Division of Neuroanatomy, University of Bonn and University Hospital Bonn, Bonn, Germany., Hochfeld LM; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Beins EC; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Kaltheuner IH; Institute of Structural Biology, University of Bonn and University Hospital Bonn, Bonn, Germany., Schmitz M; Institute of Structural Biology, University of Bonn and University Hospital Bonn, Bonn, Germany., Wöhler A; Department of General, Visceral and Thoracic Surgery, Bundeswehr Central Hospital Koblenz, Koblenz, Germany., Döhla M; Institute of Hygiene and Public Health, University of Bonn and University Hospital Bonn, Bonn, Germany.; Department of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, Koblenz, Germany., Sib E; Institute of Hygiene and Public Health, University of Bonn and University Hospital Bonn, Bonn, Germany., Jentzsch M; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany., Moench EC; MVZ Laboratory, Dr. Quade and Associates, Cologne, Germany., Borrajo JD; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Strecker J; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Reinhardt J; Institute of Experimental Oncology, University of Bonn and University Hospital Bonn, Bonn, Germany., Cleary B; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA., Geyer M; Institute of Structural Biology, University of Bonn and University Hospital Bonn, Bonn, Germany., Hölzel M; Institute of Experimental Oncology, University of Bonn and University Hospital Bonn, Bonn, Germany., Macrae R; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Nöthen MM; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany., Hoffmann P; Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany.; Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland., Exner M; Institute of Hygiene and Public Health, University of Bonn and University Hospital Bonn, Bonn, Germany., Regev A; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Klarman Cell Observatory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA., Zhang F; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Schmid-Burgk JL; Broad Institute of MIT and Harvard, Massachusetts Institute of Technology, Cambridge, MA, USA. jonathan.schmid-burgk@ukbonn.de.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA. jonathan.schmid-burgk@ukbonn.de.; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA. jonathan.schmid-burgk@ukbonn.de.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. jonathan.schmid-burgk@ukbonn.de.; Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn and University Hospital Bonn, Bonn, Germany. jonathan.schmid-burgk@ukbonn.de.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2022 Aug; Vol. 40 (8), pp. 1295.