Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ishmael M. Inocencio"'
Autor:
Amy E. Sutherland, Tegan A. White, Charmaine R. Rock, Beth R. Piscopo, Ingrid Dudink, Ishmael M. Inocencio, Zahrah Azman, Yen Pham, Ilias Nitsos, Atul Malhotra, Tamara Yawno, Graeme R. Polglase, Graham Jenkin, Emily J. Camm, Beth J. Allison, Suzanne L. Miller
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionFetal growth restriction (FGR) is a common pregnancy complication, caused by placental insufficiency, with serious adverse consequences for development in utero and postnatal wellbeing. There are no antenatal treatments to improve growth
Externí odkaz:
https://doaj.org/article/a7afa6dae9ba4286895b477cbdface19
Autor:
Gina D. Kusuma, Anqi Li, Dandan Zhu, Hannah McDonald, Ishmael M. Inocencio, Daniel C. Chambers, Kenneth Sinclair, Haoyun Fang, David W. Greening, Jessica E. Frith, Rebecca Lim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Therapeutic benefits of mesenchymal stem cells (MSCs) are now widely believed to come from their paracrine signalling, i.e. secreted factors such as cytokines, chemokines, and extracellular vesicles (EVs). Cell-free therapy using EVs is an active and
Externí odkaz:
https://doaj.org/article/3526c9826add44e1a7d4efdb26c08c96
Autor:
Beth J. Allison, Jamie Mihelakis, Arvind Sehgal, Anqi Li, Ishmael M. Inocencio, Graeme R. Polglase, Suzanne L. Miller, Amy E. Sutherland
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 39:731-740
Objective— The objective of this study was to investigate the effect of intravenous maternal sildenafil citrate (SC) administration on vascular function in growth-restricted fetal sheep. Approach and Results— Fetal growth restriction (FGR) result
Autor:
Samantha K. Barton, Kyra Y. Y. Chan, Ishmael M. Inocencio, Mary Tolcos, Stuart B. Hooper, Graeme R. Polglase, Beth J. Allison, Domenic A. LaRosa, Timothy J. M. Moss, Valerie A. Zahra, Jade Barbuto
Publikováno v:
Journal of Applied Physiology. 126:44-50
Erythropoietin (EPO) is being trialled in preterm infants to reduce brain injury, but high doses increase lung injury in ventilated preterm lambs. We aimed to determine whether early administration of lower doses of EPO could reduce ventilation-induc
Autor:
Ishmael M. Inocencio, Nhi T. Tran, Manon Wiersma, Katja Stoecker, Shinji Nakamura, Timothy J. Moss, David W. Walker, Flora Y. Wong
Publikováno v:
Experimental Neurology. 352:114049
Neurovascular coupling leads to an increase in local cerebral blood flow and oxygenation in response to increased neural activity. Reduced cerebral functional responses may predispose to tissue hypoxia when neural activity is increased. Intrauterine
Autor:
Flora Y. Wong, Nhi T. Tran, Manon Wiersma, David W. Walker, Song J. Khor, Ishmael M. Inocencio, Shinji Nakamura
Publikováno v:
Experimental neurology. 341
Background In the adult brain, increases in neural activity lead to increases in local blood flow. However, in the preterm neonate, studies of cerebral functional haemodynamics have yielded inconsistent results, including negative responses suggestin
Publikováno v:
The Journal of Physiology
Key points Fetal growth restriction induces a haemodynamic response that aims to maintain blood flow to vital organs such as the brain, in the face of chronic hypoxaemiaMaternal sildenafil treatment impairs the hypoxaemia‐driven haemodynamic respon
Autor:
Douglas A Blank, Alison Moxham, Fiona J. Stenning, Valerie A. Zahra, Kelly J. Crossley, Ishmael M. Inocencio, Stuart B. Hooper, Karyn Rodgers, Domeic A LaRosa, Andrew W. Gill, Martin Kluckow, Graeme R. Polglase, Peter G Davis
Publikováno v:
Archives of Disease in Childhood. Fetal and Neonatal Edition
ObjectiveUmbilical cord milking (UCM) at birth may benefit preterm infants, but the physiological effects of UCM are unknown. We compared the physiological effects of two UCM strategies with immediate umbilical cord clamping (UCC) and physiological-b
Autor:
Magdalena Plebanski, Ishmael M. Inocencio, Jade Barbuto, Sue D. Xiang, Domenic A. LaRosa, Valerie A. Zahra, Robert J Bischof, Vy Nguyen, Mary Tolcos, Tammy Lim, Timothy J. M. Moss, Graeme R. Polglase
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Mechanical ventilation of preterm neonates causes lung inflammation and injury, with potential life-long consequences. Inert 50-nm polystyrene nanoparticles (PS50G) reduce allergic inflammation in the lungs of adult mice. We aimed to confirm the anti
Autor:
Stuart B. Hooper, Peter G Davis, Domenic A. LaRosa, Andrew W. Gill, Martin Kluckow, Graeme R. Polglase, Douglas A Blank, Valerie A. Zahra, Karyn Rodgers, Corinna Binder-Heschl, Ishmael M. Inocencio, Alison Moxham
Publikováno v:
Journal of Paediatrics and Child Health. 52:643-648
Aim Pneumothorax is a common emergency affecting extremely preterm. In adult studies, lung ultrasound has performed better than chest x-ray in the diagnosis of pneumothorax. The purpose of this study was to determine the efficacy of lung ultrasound (