Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ishita S, Mehta"'
Autor:
Ishita S. Mehta, Kumars Riyahi, Rita Torres Pereira, Karen J. Meaburn, Martin Figgitt, Ian R. Kill, Christopher H. Eskiw, Joanna M. Bridger
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
This study demonstrates, and confirms, that chromosome territory positioning is altered in primary senescent human dermal fibroblasts (HDFs). The chromosome territory positioning pattern is very similar to that found in HDFs made quiescent either by
Externí odkaz:
https://doaj.org/article/05d60265ec75408abded1657357ca06f
Autor:
Christopher H. Eskiw, Ishita S. Mehta, Joanna M. Bridger, Kumars Riyahi, Karen J. Meaburn, Martin Figgitt, Rita Torres Pereira, Ian R. Kill
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
This study demonstrates, and confirms, that chromosome territory positioning is altered in primary senescent human dermal fibroblasts (HDFs). The chromosome territory positioning pattern is very similar to that found in HDFs made quiescent either by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02403a0a5cf83aaf992a0996f3ed9644
https://www.frontiersin.org/articles/10.3389/fcell.2021.640200/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.640200/full
Publikováno v:
Nucleus. 8:449-460
Among the many facets of DNA damage response (DDR), relocation of chromosome territories (CTs) is most intriguing. We have previously reported that cisplatin induced DDR in human dermal fibroblasts led to relocation of CTs 12, 15 from the nuclear per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d65848eccfd542aa6b090fffab7f5d
https://doi.org/10.1080/19491034.2017.1313938
https://doi.org/10.1080/19491034.2017.1313938
Publikováno v:
Scientific Reports
Forty-six chromosome territories (CTs) are positioned uniquely in human interphase nuclei, wherein each of their positions can range from the centre of the nucleus to its periphery. A non-empirical basis for their non-random arrangement remains unrep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89959191743866d81eff4cbbe853b652
Publikováno v:
Nucleic Acids Research
During DNA damage response (DDR), certain gene rich chromosome territories (CTs) relocate to newer positions within interphase nuclei and revert to their native locations following repair. Such dynamic relocation of CTs has been observed under variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f5f66862ee650f580fe8de83bae958
https://pubmed.ncbi.nlm.nih.gov/28640660
https://pubmed.ncbi.nlm.nih.gov/28640660
Forty-six chromosome territories (CTs) are positioned uniquely in the human interphase nuclei, wherein each of their position can range from the center of the nucleus to its periphery. A non-empirical basis for their non-random arrangement remains un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cba61ac533056c7f6d86c9afa2e92f8
Publikováno v:
Biochemical Society Transactions. 38:287-291
HGPS (Hutchinson–Gilford progeria syndrome) is a rare genetic disease affecting children causing them to age and die prematurely. The disease is typically due to a point mutation in the coding sequence for the nuclear intermediate-type filament pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518d957afe2b34bfe39cc17a1b5d594f
https://doi.org/10.1042/bst0380287
https://doi.org/10.1042/bst0380287
Publikováno v:
Annals of the New York Academy of Sciences. 1100:250-263
The organization of the genome within interphase nuclei, and how it interacts with nuclear structures is important for the regulation of nuclear functions. Many of the studies researching the importance of genome organization and nuclear structure ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0b173f822bbbba10660b350b1f9531
https://doi.org/10.1196/annals.1395.027
https://doi.org/10.1196/annals.1395.027
Publikováno v:
The Nucleus ISBN: 9781493916795
The spatial organization of the genome within the interphase nucleus is important for mediating genome functions. The radial organization of chromosome territories has been studied traditionally using two-dimensional fluorescence in situ hybridizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b39a1a83ff4c02f4322cc337033e33b
https://doi.org/10.1007/978-1-4939-1680-1_17
https://doi.org/10.1007/978-1-4939-1680-1_17
Autor:
Joanna M, Bridger, Halime D, Arican-Gotkas, Helen A, Foster, Lauren S, Godwin, Amanda, Harvey, Ian R, Kill, Matty, Knight, Ishita S, Mehta, Mai Hassan, Ahmed
Publikováno v:
Advances in experimental medicine and biology. 773
The genomes of a wide range of different organisms are non-randomly organized within interphase nuclei. Chromosomes and genes can be moved rapidly, with direction, to new non-random locations within nuclei upon a stimulus such as a signal to initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d470b7587710dcb6204d2af96b18faf
https://pubmed.ncbi.nlm.nih.gov/24563352
https://pubmed.ncbi.nlm.nih.gov/24563352