Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ishari Silva"'
Autor:
Nirmani Yasara, Nethmi Wickramarathne, Chamila Mettananda, Ishari Silva, Nizri Hameed, Kumari Attanayaka, Rexan Rodrigo, Nirmani Wickramasinghe, Lakshman Perera, Aresha Manamperi, Anuja Premawardhena, Sachith Mettananda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hydroxyurea is an antimetabolite drug that induces fetal haemoglobin in sickle cell disease. However, its clinical usefulness in β-thalassaemia is unproven. We conducted a randomised, double-blind, placebo-controlled clinical trial to evalu
Externí odkaz:
https://doaj.org/article/4cc1a47132c94b1ba3eb73830eb877e0
Autor:
Padmapani Padeniya, Shirom Siriwardana, Dileepa Ediriweera, Nayana Samarasinghe, Sasanka Silva, Ishari Silva, Nizri Ahamed, Madunil Niriella, Anuja Premawardhena
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-4 (2020)
Abstract To compare the similarity of the non-patented T2* and the high cost patented R2 (Ferriscan®) MRI techniques in the measurement of liver iron concentration (LIC) in heavily transfused patients with thalassaemia major in a real- life Sri Lank
Externí odkaz:
https://doaj.org/article/4448545c25b948ac86a9c4b8c7645eaf
Autor:
Shiromi Perera, Angela Allen, Ishari Silva, Menaka Hapugoda, M. Nirmali Wickramarathne, Indira Wijesiriwardena, Stephen Allen, David Rees, Dimitar G. Efremov, Christopher A. Fisher, David J. Weatherall, Anuja Premawardhena
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract β thalassaemia intermedia (βTI) are a heterogeneous group of disorders known to be extremely phenotypically diverse. This group is more complex to manage as no definitive treatment guidelines exist unlike for β thalassaemia major (βTM).
Externí odkaz:
https://doaj.org/article/6778d9b209994bc0ba59c70f57f95b78
Autor:
Anuja Premawardhena, Roshanthi Fernando, Sumudu Kumarage, Nilanga Nishad, Dilith Goonatilleke, Ishari Silva, Sachith Mettananda
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Objective At present, cholecystectomy is carried out for thalassaemia patients with gall stone disease only if they develop symptoms of cholecystitis, except in the rare instance where an un-inflammed gall bladder is removed simultaneously w
Externí odkaz:
https://doaj.org/article/22aea509b0844a8bb249f97a5334cc24
Autor:
Angela Allen, Shiromi Perera, Luxman Perera, Rexan Rodrigo, Sachith Mettananda, Agnes Matope, Ishari Silva, Nizri Hameed, Christopher A. Fisher, Nancy Olivieri, David J. Weatherall, Stephen Allen, Anuja Premawardhena
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Introduction: The high frequencies of carriers of severe haemoglobinopathies and of iron deficiency in Southeast Asia require reliable and affordable tests to improve on current screening procedures.Objectives: We evaluate a “one stop” approach u
Externí odkaz:
https://doaj.org/article/2d30e2530cdb4a3cb214af3e58fd6ca2
Autor:
Anuja P Premawardhana, Rasnayaka Mudiyanse, Shamila T De Silva, Nilam Jiffry, Udaya Nelumdeniya, Udaya de Silva, Sanath P Lamabadusuriya, K Pushpakumara, Randima Dissanayaka, M Jansz, I Rifaya, Upul Navarathne, V Thirukumaran, Mahinda Arambepola, Wijesundara Dayanada Bandara, U Vaidyanatha, Devan Mendis, K Weerasekara, Nalika De Silva, D K Shantha Kumara, Sujeewa D Amarasena, K K Hemantha, M A C M Refai, Ishari Silva, Nizri Hameed, F Rajiyah, Sachith Mettananda, Angela Allen, David J Weatherall, Nancy F Oliveri
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220852 (2019)
ObjectivesOur aim was to describe the numbers and distribution of patients with different types of thalassemia and to assess the standards of care in all thalassemia treatment centers throughout Sri Lanka and the success of the ongoing prevention pro
Externí odkaz:
https://doaj.org/article/a7a803911fcf42efb6d434bb61b19f3e
Autor:
Nirmani Yasara, Nethmi Wickramarathne, Chamila Mettananda, Ishari Silva, Nizri Hameed, Kumari Attanayaka, Rexan Rodrigo, Nirmani Wickramasinghe, Lakshman Perera, Aresha Manamperi, Anuja Premawardhena, Sachith Mettananda
Publikováno v:
Scientific reports. 12(1)
Hydroxyurea is an antimetabolite drug that induces fetal haemoglobin in sickle cell disease. However, its clinical usefulness in β-thalassaemia is unproven. We conducted a randomised, double-blind, placebo-controlled clinical trial to evaluate the e
Autor:
Udaya B. Nelumdeniya, Sanath P Lamabadusuriya, Shamila T De Silva, K.R.C. Pushpakumara, Anuja P Premawardhana, Udaya de Silva, Ishari Silva, Sujeewa D Amarasena, F Rajiyah, Nizri Hameed, K.P. Weerasekara, K K Hemantha, M. Arambepola, I Rifaya, M. Jansz, Nalika De Silva, Upul Navarathne, U Vaidyanatha, D K Shantha Kumara, RM Mudiyanse, V. Thirukumaran, Randima Dissanayaka, Wijesundara Dayanada Bandara, Devan Mendis, Sachith Mettananda, Nilam Jiffry, Angela Allen, Nancy F Oliveri, David J. Weatherall, M.A.C.M. Refai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0220852 (2019)
PLoS ONE, Vol 14, Iss 8, p e0220852 (2019)
ObjectivesOur aim was to describe the numbers and distribution of patients with different types of thalassemia and to assess the standards of care in all thalassemia treatment centers throughout Sri Lanka and the success of the ongoing prevention pro
Autor:
Madunil A. Niriella, David Bonsall, S. Perera, Mariateresa de Cesare, Angela Allen, Anuja Premawardhena, Randima Dissanayake, Paul Klenerman, David J. Roberts, Udaya B. Nelumdeniya, David J. Weatherall, Ishari Silva, Anura C. Peries
Publikováno v:
Transfusion medicine (Oxford, England)REFERENCES. 30(5)
Objectives To report the clinical and virologic epidemiology of a recent epidemic of hepatitis C in thalassaemia patients in Sri Lanka. Background Transfusion‐dependent thalassaemia patients remain at risk for hepatitis C virus (HCV). Here, we repo
Autor:
David J. Weatherall, Shantha Hettiarachchi, Nizri Hameed, Taraka Pilapitiya, Gihan Weerasinghe, Nancy F. Olivieri, Ishari Silva, Arunasalam Pathmeswaran, Udaya K. Ranawaka, A. Hapangama, K.A. Salvin, Mark W Weatherall, Anuja Premawardhena
Publikováno v:
British journal of haematology. 185(3)
Neurological manifestations are reported only occasionally in patients with thalassaemia and are given much less prominence than the complications related to anaemia and iron overload. White matter changes (WMCs) on magnetic resonance imaging (MRI) i