Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ishara F Azmi"'
Autor:
Ishara F Azmi, Shinya Watanabe, Michael F Maloney, Sukhyun Kang, Jason A Belsky, David M MacAlpine, Craig L Peterson, Stephen P Bell
Publikováno v:
eLife, Vol 6 (2017)
Eukaryotic replication origin licensing, activation and timing are influenced by chromatin but a mechanistic understanding is lacking. Using reconstituted nucleosomal DNA replication assays, we assessed the impact of nucleosomes on replication initia
Externí odkaz:
https://doaj.org/article/521e37a5772a4be499b9d91e1175b534
Autor:
Matthew West, Natalya Pashkova, Shirley Dean, Ishara F. Azmi, Robert C. Piper, Brian A. Davies, Johanna A. Payne, Jennifer Staffenhagen, David J. Katzmann, Greg Odorizzi, Chun-Che Tseng
Publikováno v:
The Journal of Cell Biology
Endosomal sorting complexes required for transport (ESCRT-0, -I, -II, -III) execute cargo sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to multivesicular bodies (MVBs). The AAA-ATPase Vps4 regulates the ESCRT-III pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7487c51b0fce23de64cc90d1ad8285
https://doi.org/10.1083/jcb.20210207007022021c
https://doi.org/10.1083/jcb.20210207007022021c
Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis
Autor:
Jennifer Staffenhagen, Ishara F. Azmi, Natalya Pashkova, Johanna A. Payne, Brian A. Davies, Greg Odorizzi, David J. Katzmann, Chun-Che Tseng, Matthew West, Robert C. Piper, Shirley Dean
Publikováno v:
The Journal of Cell Biology
Tseng et al. show the Bro1 V domain stimulates Vps4 to promote ESCRT-III–driven intralumenal vesicle formation. This mode of stimulation is required for coordinated cargo incorporation during ESCRT-mediated multivesicular body biogenesis.
Endo
Endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bc7841e2ffda1eec51def419214ecc
https://doi.org/10.1083/jcb.202102070
https://doi.org/10.1083/jcb.202102070
Autor:
Chun-Che Tseng, David J. Katzmann, Jennifer Staffenhagen, Johanna A. Payne, Matthew West, Shirley Dean, Natalya Pashkova, Ishara F. Azmi, Robert C. Piper, Greg Odorizzi, Brian A. Davies
Endosomal sorting complexes required for transport (ESCRT-0, -I, -II, -III) execute cargo sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to multivesicular bodies (MVBs). The AAA-ATPase Vps4 regulates the ESCRT-III pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b52e45e642568dd56dc42f80d9456543
https://doi.org/10.1101/2020.07.27.223255
https://doi.org/10.1101/2020.07.27.223255
Publikováno v:
Other repository
In eukaryotes, DNA replication initiates from multiple origins of replication for timely genome duplication. These sites are selected by origin licensing, during which the core enzyme of the eukaryotic DNA replicative helicase, the Mcm2-7 (minichromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2dac1094d63636f33ab2339d8da403
https://europepmc.org/articles/PMC5766963/
https://europepmc.org/articles/PMC5766963/
Autor:
Craig L. Peterson, Stephen P. Bell, Sukhyun Kang, Shinya Watanabe, Ishara F. Azmi, Michael F. Maloney, David M. MacAlpine, Jason A. Belsky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72c83ab2486c43d304c13a779ece93a4
https://doi.org/10.7554/elife.22512.030
https://doi.org/10.7554/elife.22512.030
Autor:
David J. Katzmann, Johanna A. Payne, Anna Shestakova, Bruce F. Horazdovsky, Ishara F. Azmi, Markus Babst, Brian A. Davies
Publikováno v:
Molecular Biology of the Cell
Vps4 disassembly of ESCRT-III plays an important role in MVB sorting, viral budding, and cytokinesis. An in vitro system was developed to investigate this process. These studies revealed new insights into the mechanisms of Vps4 function.
ESCRT-I
ESCRT-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c34dda8c40ac51250d8255e49fc3da1
http://europepmc.org/articles/PMC2947475
http://europepmc.org/articles/PMC2947475
Publikováno v:
Developmental Cell. 14:50-61
The AAA-ATPase Vps4 is critical for function of the MVB sorting pathway, which in turn impacts cellular phenomena ranging from receptor downregulation to viral budding to cytokinesis. Vps4 dissociates ESCRTs from endosomal membranes during MVB sortin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d0f1b50c1f8cba6605455f3a19620f
https://doi.org/10.1016/j.devcel.2007.10.021
https://doi.org/10.1016/j.devcel.2007.10.021
Autor:
Ishara F. Azmi, Andrea J. Oestreich, Jacqueline R. E. Lee, Mariam Aboian, David J. Katzmann, Rachel B. Issaka, Johanna A. Payne, Brian A. Davies
Publikováno v:
Molecular Biology of the Cell. 18:707-720
A subset of proteins that transit the endosomal system are directed into the intralumenal vesicles of multivesicular bodies (MVBs). MVB formation is critical for a variety of cellular functions including receptor down-regulation, viral budding, antig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81225efc2e50bc430b12ad12aaf33777
https://doi.org/10.1091/mbc.e06-08-0680
https://doi.org/10.1091/mbc.e06-08-0680
Autor:
Johanna A. Payne, Markus Babst, Ishara F. Azmi, David J. Katzmann, Christian Dimaano, Brian A. Davies, Debra M. Eckert
Publikováno v:
The Journal of Cell Biology
In eukaryotes, the multivesicular body (MVB) sorting pathway plays an essential role in regulating cell surface protein composition, thereby impacting numerous cellular functions. Vps4, an ATPase associated with a variety of cellular activities, is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39dce4fce177a2202e70263845a410e2
http://europepmc.org/articles/PMC2063703
http://europepmc.org/articles/PMC2063703