Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Ishaque P. Kadamberi"'
1
Akademický článek
Blocking Oncostatin M receptor abrogates STAT3 mediated integrin signaling and overcomes chemoresistance in ovarian cancer
Autor: Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P. Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapy such as cisplatin is widely used to treat ovarian cancer either before or after surgical debulking. However, cancer relapse due to chemotherapy resistance is a major challenge in the treatment of ovarian cancer. The underlying m
Externí odkaz: https://doaj.org/article/ef81d450abe040d3a9700614472c2f15
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3
Akademický článek
Optimized proximity ligation assay (PLA) for detection of RNA-protein complex interactions in cell lines
Autor: Jasmine George, Sonam Mittal, Ishaque P. Kadamberi, Sunila Pradeep, Pradeep Chaluvally-Raghavan
Publikováno v: STAR Protocols, Vol 3, Iss 2, Pp 101340- (2022)
Summary: Conventional proximity ligation assay (PLA) suffers from target specificity issues that curtail their accuracy on interpreting proximal interactions in cell biology. Here, we present a reliable and sensitive approach by including a fluorochr
Externí odkaz: https://doaj.org/article/be2a8c20427d40fc99b41192d0c746af
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4
Akademický článek
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
Autor: Jasmine George, Yongsheng Li, Ishaque P. Kadamberi, Deepak Parashar, Shirng-Wern Tsaih, Prachi Gupta, Anjali Geethadevi, Changliang Chen, Chandrima Ghosh, Yunguang Sun, Sonam Mittal, Ramani Ramchandran, Hallgeir Rui, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Gustavo Leone, Janet S. Rader, Anil K. Sood, Madhusudan Dey, Sunila Pradeep, Pradeep Chaluvally-Raghavan
Publikováno v: Cell Reports, Vol 37, Iss 5, Pp 109934- (2021)
Summary: Fragile X-related protein-1 (FXR1) gene is highly amplified in patients with ovarian cancer, and this amplification is associated with increased expression of both FXR1 mRNA and protein. FXR1 expression directly associates with the survival
Externí odkaz: https://doaj.org/article/1bda5605c1c8465997ff1e6038dd99f9
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5
Akademický článek
Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer
Autor: Prachi Gupta, Ishaque Pulikkal Kadamberi, Sonam Mittal, Shirng‐Wern Tsaih, Jasmine George, Sudhir Kumar, Dileep K. Vijayan, Anjali Geethadevi, Deepak Parashar, Paytsar Topchyan, Lindsey McAlarnen, Brian F Volkman, Weiguo Cui, Kam Y. J. Zhang, Dolores Di Vizio, Pradeep Chaluvally‐Raghavan, Sunila Pradeep
Publikováno v: Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract SPHK1 (sphingosine kinase‐1) catalyzes the phosphorylation of sphingosine to sphingosine‐1‐phosphate (S1P), is found to be highly expressed in solid tumors. Here, extracellular vesicles (EVs) are identified as the key transporters of S
Externí odkaz: https://doaj.org/article/f06bbfca07794a258533a5731cd75e20
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