Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ishani Savant"'
Autor:
Zheng, Naiyu, Zeng, Jianing, Ji, Qin C., Angeles, Aida, Aubry, Anne-Francoise, Basdeo, Shenita, Buzescu, Adela, Landry, Ishani Savant, Jariwala, Navin, Turley, Wesley, Burrell, Richard, Arnold, Mark E.
Publikováno v:
In Analytica Chimica Acta 31 August 2016 934:170-179
Akademický článek
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Autor:
Christoph Gesenberg, Neil Mathias, John R. Crison, Ishani Savant, Naiyu Zheng, David Good, Richard Schartman, Yan Xu, Jeffrey N. Hemenway, Jatin M. Patel, Adela Buzescu, Amy Saari, Ajit S. Narang
Publikováno v:
Pharmaceutical Research. 36
To describe a stepwise approach to evaluate the pH effect for a weakly basic drug by in vitro, in vivo and in silico techniques and identify a viable mitigation strategy that addresses the risk. Clinical studies included assessment of the pH effect w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab06a5afd85d7ca3103de05c31a7516
https://doi.org/10.1007/s11095-019-2698-0
https://doi.org/10.1007/s11095-019-2698-0
Autor:
C. Hyung Park, Mahmoud Assaf, Maria Palmisano, Simon Zhou, Anfan Wu, Yong Liu, Liangang Liu, Ishani Savant
Publikováno v:
International Journal of Clinical Pharmacology and Therapeutics
Objective: This study was conducted to evaluate the effect of apremilast and its major metabolites on the placebo-corrected change-from-baseline QTc interval of an electrocardiogram (ECG). Materials and methods: Healthy male subjects received each of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e74db84fcc2ec20ef73e7df7d2e6440
http://europepmc.org/articles/PMC4949396
http://europepmc.org/articles/PMC4949396
Autor:
Sadaharu Kotani, Ishani Savant-Landry, Robert Lai, Johan Luthman, Edgar Schuck, Ziad Hussein, Mitsuhiro Ino, Min-Kun Chang, Jagadeesh Aluri
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ce3e69ec8ee1813621d97b63de7a1a
https://doi.org/10.1016/j.jalz.2017.06.123
https://doi.org/10.1016/j.jalz.2017.06.123
Autor:
Max Lataillade, Malaz Abu Tarif, Li Zhu, Samit R Joshi, Matthew Hruska, Ishani Savant Landry, Maria Pitsiu, David W. Boulton, George J. Hanna, Richard Bertz, Brian M. Sadler
BMS-663068 is an oral prodrug of the HIV-1 attachment inhibitor BMS-626529, which prevents viral attachment to host CD4 + T cells by binding to HIV-1 gp120. To guide dose selection for the phase 3 program, pharmacokinetic/pharmacodynamic modeling was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7631a914f6e2710b43450e5a8181891b
https://europepmc.org/articles/PMC4862460/
https://europepmc.org/articles/PMC4862460/
Autor:
Anne-Françoise Aubry, Richard C. Burrell, Mark E. Arnold, Wesley A. Turley, Qin C Ji, Naiyu Zheng, Ishani Savant Landry, Shenita Basdeo, Jianing Zeng, Navin Jariwala, Adela Buzescu, Aida Angeles
Publikováno v:
Analytica chimica acta. 934
Dried saliva spot (DSS) sampling is a non-invasive sample collection technique for bioanalysis that can be potentially implemented at the patient's home. A UHPLC-MS/MS assay was developed using detergent-assisted sample extraction to quantify BMS-927
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8a45cdca384cfb02816f6c9cbd5a1
https://pubmed.ncbi.nlm.nih.gov/27506357
https://pubmed.ncbi.nlm.nih.gov/27506357
Autor:
Heather Sevinsky, Sunny Chapel, Amit Roy, Man Luo, Brenda Cirincione, Ishani Savant, Richard Bertz
Publikováno v:
Antimicrobial Agents and Chemotherapy
Efavirenz (EFV) is a nonnucleoside reverse transcriptase inhibitor approved worldwide for the treatment of HIV in adults and children over 3 years of age or weighing over 10 kg. Only recently EFV was approved in children over 3 months and weighing at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f987c7e75798c421ab4d3ad7df1b7d4
https://pubmed.ncbi.nlm.nih.gov/27067333
https://pubmed.ncbi.nlm.nih.gov/27067333
Autor:
Michael T. Furlong, Carey Hwang, Ishani Savant Landry, Matthew Hruska, Vaishali Shah, George J. Hanna, Li Zhu, Richard Bertz
Publikováno v:
Antimicrobial agents and chemotherapy. 59(7)
BMS-663068 is a prodrug of BMS-626529, a first-in-class attachment inhibitor that binds directly to HIV-1 gp120, preventing initial viral attachment and entry into host CD4+T cells. This open-label, multiple-dose, four-sequence, crossover study addre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3998868c80ac2a3845a20540316a5b24
https://pubmed.ncbi.nlm.nih.gov/25870057
https://pubmed.ncbi.nlm.nih.gov/25870057
Autor:
Amol Tendolkar, Jun-Sheng Wang, Hong Xiao, Richard Malamut, Oleksandr Sverdlov, Sanjay Keswani, Ishani Savant
Publikováno v:
Alzheimer's & Dementia. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94bfa16c04a2b09911a46d729672b50
https://doi.org/10.1016/j.jalz.2013.05.1378
https://doi.org/10.1016/j.jalz.2013.05.1378