Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ishan Wadi"'
Publikováno v:
Journal of Vector Borne Diseases, Vol 56, Iss 3, Pp 189-199 (2019)
Background & objectives: Malaria has remained a global health problem despite the effective control and treatment measures. In the backdrop of drug resistance, developing novel hybrid molecules targeting the sexual stages (gametocytes) of the human m
Externí odkaz:
https://doaj.org/article/1e58bdaffde54bc7b8814ac22901b414
Autor:
Ishan Wadi, C. Radhakrishna Pillai, Anupkumar R. Anvikar, Abhinav Sinha, Mahendra Nath, Neena Valecha
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-9 (2018)
Abstract Background Malaria remains a global health problem despite availability of effective tools. For malaria elimination, drugs targeting sexual stages of Plasmodium falciparum need to be incorporated in treatment regimen along with schizonticida
Externí odkaz:
https://doaj.org/article/393f1f4a94a84921a0e54bc09166e003
Autor:
Neha Batra, Drishti Agarwal, Ishan Wadi, Chandra Sekhar Tekuri, Rinkoo D Gupta, Mahendra Nath
Publikováno v:
Future Medicinal Chemistry. 14:1725-1739
Aim & background: Drugs with multiple bioactive moieties have the advantages of multiple modes of action and fewer chances of drug resistance. In continuation of our previous work of developing hybrid antimalarials, we present herein the synthesis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce77b6f869d2303118628c6f4bbdb97
https://doi.org/10.4155/fmc-2022-0187
https://doi.org/10.4155/fmc-2022-0187
Publikováno v:
3 Biotech
The fundamental requirement of every gametocytocidal drug screening assay is the sufficient numbers of healthy and viable gametocytes. The number of in vitro gametocytes grossly depends on the genetic capacity of parasites to produce gametocytes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc4132e05c113ee855d12668941edf6
https://europepmc.org/articles/PMC7801553/
https://europepmc.org/articles/PMC7801553/
Publikováno v:
Journal of vector borne diseases. 56(3)
Malaria has remained a global health problem despite the effective control and treatment measures. In the backdrop of drug resistance, developing novel hybrid molecules targeting the sexual stages (gametocytes) of the human malaria parasite Plasmodiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dbf0e933f7050994eefe7dcb1672f43
https://pubmed.ncbi.nlm.nih.gov/32655067
https://pubmed.ncbi.nlm.nih.gov/32655067
Publikováno v:
Future medicinal chemistry. 12(11)
As the world gets closer to eliminating malaria, the scientific community worldwide has begun to realize the importance of malaria transmission-blocking interventions. The onus of breaking the life cycle of the human malaria parasite Plasmodium falci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4295c4c1dab2021f18da5c2ddda0f38
https://pubmed.ncbi.nlm.nih.gov/32378423
https://pubmed.ncbi.nlm.nih.gov/32378423
Autor:
C. Radhakrishna Pillai, Neena Valecha, Mahendra Nath, Ishan Wadi, Abhinav Sinha, Anupkumar R. Anvikar
Publikováno v:
Future Medicinal Chemistry. 10:2619-2639
In the absence of clinically proven vaccines and emerging resistance to common antimalarials and insecticides, the onus of interrupting the life cycle of Plasmodium falciparum, is upon the transmission-blocking drugs. Current transmission-blocking dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82f6830350436041264f73dcf912433
https://doi.org/10.4155/fmc-2018-0169
https://doi.org/10.4155/fmc-2018-0169
Autor:
Ishan Wadi, Prahlad C. Ghosh, Vinoth Rajendran, Rinkoo D. Gupta, Drishti Agarwal, Mahendra Nath, Neha Batra
Publikováno v:
ChemistrySelect. 3:9790-9793
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32cb6486cb5d5d780148781dcf053eb
https://doi.org/10.1002/slct.201801905
https://doi.org/10.1002/slct.201801905
Publikováno v:
Infection, Genetics and Evolution. 92:104848
In spite of a decrease in malaria cases, the threat of malaria due to Plasmodium falciparum still prevails. The sequencing of Plasmodium falciparum reveals that approximately 60% of the Plasmodium genes code for hypothetical/putative proteins. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5297695047e851205f1e95a51d0b6c43
https://doi.org/10.1016/j.meegid.2021.104848
https://doi.org/10.1016/j.meegid.2021.104848
Publikováno v:
Future medicinal chemistry. 11(23)
The scientific community worldwide has realized that malaria elimination will not be possible without development of safe and effective transmission-blocking interventions. Primaquine, the only WHO recommended transmission-blocking drug, is not exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3f6f9f27264b34adadea8de4b5f338
https://pubmed.ncbi.nlm.nih.gov/31782936
https://pubmed.ncbi.nlm.nih.gov/31782936