Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ishai Karton"'
Autor:
Rachel Haring, Daniele Marciano, Eliahu Heldman, David Gurwitz, Haim Meshulam, Rachel Brandeis, Abraham Fisher, Dov Barak, Ishai Karton, Zipora Pittel, Zvi Vogel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:839-844
Rigid analogs of acetylcholine offer an opportunity for selective actions at muscarinic receptor subtypes, since restricted conformational mobility alters the capacity of ligands to adapt to subtle differences in receptor structure. AF102B , a highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d02494e2795d848cb0c6fde76898d0
https://doi.org/10.1016/s0960-894x(00)80541-7
https://doi.org/10.1016/s0960-894x(00)80541-7
Autor:
Rachel Haring, Abraham Fisher, Zipora Pittel, David Gurwitz, Rachel Brandeis, Dov Barak, Claire M. Fraser, Eliahu Heldman, Ishai Karton
Publikováno v:
Cholinergic Basis for Alzheimer Therapy ISBN: 9781489967404
The presynaptic cholinergic deficits in Alzheimer’s disease (AD) indicate that a cholinergic replacement therapy might be beneficial in alleviating some of the cognitive dysfunctions in this disorder (Bartus, 1989). However, clinical trials with so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8718875791808153a24a9585703d56eb
https://doi.org/10.1007/978-1-4899-6738-1_38
https://doi.org/10.1007/978-1-4899-6738-1_38
Autor:
Abraham Fisher, Aharon Levy, Rachel Brandeis, Shlomit Dachir, Eliahu Heldman, Ishai Karton, M. Sapir, Z. Pittel
Publikováno v:
Neuroscience letters. 102(2-3)
(±)- cis -2-Methyl-spiro(1,3-oxathiolane-5,3′)quinuclidine (AF102B), a new muscarinic agonist of utmost rigidity, exhibits a high selectivity for M 1 muscarinic receptors. In rats having a cholinergic hypofunction induced by the intracerebroventri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3131995ed95d5c3de68ac8b4c003598c
https://pubmed.ncbi.nlm.nih.gov/2812509
https://pubmed.ncbi.nlm.nih.gov/2812509
Autor:
Eliahu Heldman, Abraham Fisher, Yona Grunfeld, Zipora Pittel, Rachel Brandeis, Aharon Levy, Ishai Karton, Shlomit Dachir, M. Sapir
Publikováno v:
Advances in Behavioral Biology ISBN: 9781468457292
Alzheimer’s disease (AD), a progressive cerebral neurodegenerative disorder with no effective treatment as yet, is known to affect 5–7% of the population over age 65. This disorder is characterized by a progressive deterioration of cognitive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::365ba1f6d055edfb2dce8b61bd71f17a
https://doi.org/10.1007/978-1-4684-5727-8_2
https://doi.org/10.1007/978-1-4684-5727-8_2