Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Isha A. Lokurkar"'
Autor:
Daniel K. Nomura, Theodore M. Kamenecka, Patrick R. Griffin, Leslie A. Bateman, Bruce M. Spiegelman, Hua Lin, Katrin J. Svensson, Jonathan Z. Long, Mi Ra Chang, Rajesh R. Rao, Joao A. Paulo, Steven P. Gygi, Isha A. Lokurkar, Mark P. Jedrychowski, Jesse Lou
Publikováno v:
Cell, vol 166, iss 2
Summary Brown and beige adipocytes are specialized cells that express uncoupling protein 1 (UCP1) and dissipate chemical energy as heat. These cells likely possess alternative UCP1-independent thermogenic mechanisms. Here, we identify a secreted enzy
Autor:
Jonathan Z. Long, Rajesh R. Rao, Wendy Baur, Isha A. Lokurkar, Xingxing Kong, Katrin J. Svensson, Linus T.-Y. Tsai, John J. Castellot, Hyun Cheol Roh, Jesse Lou, Evan D. Rosen, Bruce M. Spiegelman, Xing Zeng
Publikováno v:
Cell Metabolism. 19:810-820
SummaryThermogenic UCP1-positive cells, which include brown and beige adipocytes, transform chemical energy into heat and increase whole-body energy expenditure. Using a ribosomal profiling approach, we present a comprehensive molecular description o
Autor:
Isha A. Lokurkar, Jonathan Z. Long, Lykke Sylow, Erik A. Richter, Xing Zeng, Bruce M. Spiegelman
Dasatinib (Sprycel) is a tyrosine kinase inhibitor approved for treatment of chronic myeloid leukemia. In this study, we identify dasatinib as a potent inducer of Peroxisome proliferator-activated receptor gamma coactivator (PGC)-1α mRNA. Dasatinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0846a72fdad2f283804e224a9575d8
https://europepmc.org/articles/PMC5086530/
https://europepmc.org/articles/PMC5086530/
Autor:
Donny M. Camera, John A. Hawley, Mark P. Jedrychowski, Jasbir Seehra, Katrin J. Svensson, James P. White, Jorge L. Ruas, Jonathan Z. Long, Rajesh R. Rao, Christiane D. Wrann, Jenn Lachey, Jesse Lou, Isha A. Lokurkar, Bruce M. Spiegelman, James C. Lo, Steven P. Gygi
SummaryExercise training benefits many organ systems and offers protection against metabolic disorders such as obesity and diabetes. Using the recently identified isoform of PGC1-α (PGC1-α4) as a discovery tool, we report the identification of mete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c266a0823f9e352b97c8beb5d405758
https://europepmc.org/articles/PMC4131287/
https://europepmc.org/articles/PMC4131287/