No Observed Effect Level (NOEL) for Systemic Inflammation by Copper and Zinc in Welding Fumes.

Autor: Brand P; Institute for Occupational, Social and Environmental Medicine, Medical Faculty (Mr Brand, Mr Beilmann, Mr Kraus, Ms Krabbe, Ms Merizian); Institut für Schweiß- und Fügetechnik (ISF) Welding and Joining Institute (Mr Krichel, Ms Schmidt), Rheinisch Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany., Beilmann V, Krichel T, Merizian J, Schmidt K, Kraus T, Krabbe J

Publikováno v: Journal of occupational and environmental medicine [J Occup Environ Med] 2020 Sep; Vol. 62 (9), pp. 718-723.

The pro-inflammatory stimulus of zinc- and copper-containing welding fumes in whole blood assay via protein tyrosine phosphatase 1B inhibition.

Autor: Bleidorn J; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany., Alamzad-Krabbe H; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany., Gerhards B; ISF- Welding and Joining Institute, RWTH Aachen University, Pontstraße 49, 52062, Aachen, Germany., Kraus T; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany., Brand P; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany., Krabbe J; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany. jkrabbe@ukaachen.de., Martin C; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.

Publikováno v: Scientific reports [Sci Rep] 2019 Feb 04; Vol. 9 (1), pp. 1315. Date of Electronic Publication: 2019 Feb 04.

The effects of zinc- and copper-containing welding fumes on murine, rat and human precision-cut lung slices.

Autor: Krabbe J; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany. Electronic address: jkrabbe@ukaachen.de., Esser A; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Kanzler S; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany., Braunschweig T; Institute of Pathology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Kintsler S; Institute of Pathology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Spillner J; Departement of Thoracic and Cardiovascular Surgery, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Schröder T; Department of Surgery, Luisenhospital Aachen, Boxgraben 99, 52064 Aachen, Germany., Kalverkamp S; Departement of Thoracic and Cardiovascular Surgery, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Balakirski G; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany; Departement of Dermatology and Allergology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Gerhards B; ISF- Welding and Joining Institute, RWTH Aachen University, Pontstraße 49, 52062 Aachen, Germany., Rieg AD; Department of Anaesthesiology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Kraus T; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Brand P; Institute of Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany., Martin C; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Wendlingweg 2, 52074 Aachen, Germany.

Publikováno v: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) [J Trace Elem Med Biol] 2018 Sep; Vol. 49, pp. 192-201. Date of Electronic Publication: 2018 Mar 10.

IL-6, a central acute-phase mediator, as an early biomarker for exposure to zinc-based metal fumes.

Autor: Baumann R; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany. Electronic address: RBaumann@ukaachen.de., Joraslafsky S; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Markert A; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Rack I; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Davatgarbenam S; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Kossack V; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Gerhards B; ISF-Welding and Joining Institute, Aachen University of Technology, Pontstraße 49, D-52062 Aachen, Germany., Kraus T; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Brand P; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany., Gube M; Institute for Occupational and Social Medicine, Aachen University of Technology, Pauwelsstr. 30, D-52074, Aachen, Germany.

Publikováno v: Toxicology [Toxicology] 2016 Dec 12; Vol. 373, pp. 63-73. Date of Electronic Publication: 2016 Nov 02.

Human biomonitoring of aluminium after a single, controlled manual metal arc inert gas welding process of an aluminium-containing worksheet in nonwelders.

Autor: Bertram J; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany. jbertram@ukaachen.de., Brand P; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany., Hartmann L; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany., Schettgen T; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany., Kossack V; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany., Lenz K; ISF - Welding and Joining Institute, Aachen University of Technology, Pontstr. 49, 52062, Aachen, Germany., Purrio E; ISF - Welding and Joining Institute, Aachen University of Technology, Pontstr. 49, 52062, Aachen, Germany., Reisgen U; ISF - Welding and Joining Institute, Aachen University of Technology, Pontstr. 49, 52062, Aachen, Germany., Kraus T; Medical Faculty, Institute for Occupational Medicine and Social Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.

Publikováno v: International archives of occupational and environmental health [Int Arch Occup Environ Health] 2015 Oct; Vol. 88 (7), pp. 913-23. Date of Electronic Publication: 2015 Jan 18.