Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Iserman, C."'
Autor:
Martin EW; Dewpoint Therapeutics, Boston, MA, USA., Iserman C; Dewpoint Therapeutics GMBH, Dresden, Germany., Olety B; Dewpoint Therapeutics, Boston, MA, USA., Mitrea DM; Dewpoint Therapeutics, Boston, MA, USA., Klein IA; Dewpoint Therapeutics, Boston, MA, USA. Electronic address: iklein@dewpointx.com.
Publikováno v:
Journal of molecular biology [J Mol Biol] 2024 Feb 15; Vol. 436 (4), pp. 168380. Date of Electronic Publication: 2023 Dec 05.
Autor:
Boerneke, M.A., Weidmann, C.A., Sheahan, T.P., Hou, Y.J., Ekena, J., Baric, R.S., Troyanskaya, O.G., Jungreis, I., Gladfelter, A.S., Sealfon, R.S.G., Kellis, M., Roden, C.A., Weeks, K.M., Iserman, C., Theesfeld, C.L., Fritch, E.J., McLaughlin, G.A.
We report that the SARS-CoV-2 nucleocapsid protein (N-protein) undergoes liquid-liquid phase separation (LLPS) with viral RNA. N-protein condenses with specific RNA genomic elements under physiological buffer conditions and condensation is enhanced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050eb50ff3e3cfa42b101cb3072cbfdd
Autor:
Roden CA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Dai Y; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA., Giannetti CA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Seim I; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Lee M; Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0520, USA., Sealfon R; Flatiron Institute, Simons Foundation, New York, NY 10010, USA., McLaughlin GA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Boerneke MA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Iserman C; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Wey SA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., Ekena JL; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Troyanskaya OG; Flatiron Institute, Simons Foundation, New York, NY 10010, USA.; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA., Weeks KM; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA., You L; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.; Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27708, USA., Chilkoti A; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA., Gladfelter AS; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2022 Aug 12; Vol. 50 (14), pp. 8168-8192.
Autor:
Roden CA, Dai Y, Seim I, Lee M, Sealfon R, McLaughlin GA, Boerneke MA, Iserman C, Wey SA, Ekena JL, Troyanskaya OG, Weeks KM, You L, Chilkoti A, Gladfelter AS
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2021 Jun 15. Date of Electronic Publication: 2021 Jun 15.
Autor:
Rodrigues, Nelio T. L.1 (AUTHOR), Bland, Tom1,2 (AUTHOR), Ng, KangBo1,2 (AUTHOR), Hirani, Nisha1 (AUTHOR), Goehring, Nathan W.1,2 (AUTHOR) nate.goehring@crick.ac.uk
Publikováno v:
PLoS Biology. 12/9/2024, Vol. 22 Issue 12, p1-32. 32p.
Autor:
Tikhomirova, Maria A.1,2 (AUTHOR), Kuzmenko, Oleg L.3 (AUTHOR), Arifulin, Eugene A.2 (AUTHOR), Shirokova, Olesya M.4 (AUTHOR), Musinova, Yana R.1,2 (AUTHOR), Sheval, Eugene V.2,5 (AUTHOR) sheval_e@belozersky.msu.ru
Publikováno v:
International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 23, p13162. 14p.
Autor:
Iserman C; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Roden CA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Boerneke MA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sealfon RSG; Center for Computational Biology, Flatiron Institute, New York, NY, USA., McLaughlin GA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jungreis I; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Fritch EJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hou YJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ekena J; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Weidmann CA; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Theesfeld CL; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Kellis M; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Troyanskaya OG; Center for Computational Biology, Flatiron Institute, New York, NY, USA; Department of Computer Science, Princeton University, Princeton, NJ, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Weeks KM; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gladfelter AS; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: amyglad@unc.edu.
Publikováno v:
Molecular cell [Mol Cell] 2020 Dec 17; Vol. 80 (6), pp. 1078-1091.e6. Date of Electronic Publication: 2020 Nov 27.
Autor:
Shen Y; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Ruggeri FS; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Vigolo D; School of Chemical Engineering, University of Birmingham, Birmingham, United Kingdom., Kamada A; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Qamar S; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Levin A; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom., Iserman C; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Alberti S; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., George-Hyslop PS; Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.; Department of Medicine, Division of Neurology, University of Toronto and University Health Network, Toronto, Ontario, Canada., Knowles TPJ; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom. tpjk2@cam.ac.uk.; Cavendish Laboratory, University of Cambridge, Cambridge, United Kingdom. tpjk2@cam.ac.uk.
Publikováno v:
Nature nanotechnology [Nat Nanotechnol] 2020 Oct; Vol. 15 (10), pp. 841-847. Date of Electronic Publication: 2020 Jul 13.
Autor:
Iserman C; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Roden C; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Boerneke M; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sealfon R; Flatiron Institute, Simons Foundation, New York, NY, USA., McLaughlin G; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jungreis I; Broad Institute, MIT, Cambridge, MA, USA., Park C; Flatiron Institute, Simons Foundation, New York, NY, USA., Boppana A; Department of Computer Science, Princeton University, Princeton, NJ USA., Fritch E; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hou YJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Theesfeld C; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ USA., Troyanskaya OG; Flatiron Institute, Simons Foundation, New York, NY, USA.; Department of Computer Science, Princeton University, Princeton, NJ USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sheahan TP; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Weeks K; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gladfelter AS; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2020 Jun 12. Date of Electronic Publication: 2020 Jun 12.
Autor:
Iserman C; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany., Desroches Altamirano C; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; BIOTEC and CMCB, Technische Universität Dresden, Tatzberg 47/48, 01307 Dresden, Germany., Jegers C; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany., Friedrich U; Center for Molecular Biology of the University of Heidelberg, German Cancer Research Center, DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany., Zarin T; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada., Fritsch AW; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Center for Systems Biology Dresden, 01307 Dresden, Germany., Mittasch M; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Center for Systems Biology Dresden, 01307 Dresden, Germany., Domingues A; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Center for Systems Biology Dresden, 01307 Dresden, Germany., Hersemann L; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Center for Systems Biology Dresden, 01307 Dresden, Germany., Jahnel M; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; BIOTEC and CMCB, Technische Universität Dresden, Tatzberg 47/48, 01307 Dresden, Germany., Richter D; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; BIOTEC and CMCB, Technische Universität Dresden, Tatzberg 47/48, 01307 Dresden, Germany., Guenther UP; DKMS Life Science Lab GmbH, St. Petersburger Str. 2, 01069 Dresden, Germany., Hentze MW; EMBL Heidelberg, Director's Research Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany., Moses AM; Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada; Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON M5S 3B2, Canada., Hyman AA; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany., Kramer G; Center for Molecular Biology of the University of Heidelberg, German Cancer Research Center, DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany., Kreysing M; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Center for Systems Biology Dresden, 01307 Dresden, Germany., Franzmann TM; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; BIOTEC and CMCB, Technische Universität Dresden, Tatzberg 47/48, 01307 Dresden, Germany., Alberti S; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; BIOTEC and CMCB, Technische Universität Dresden, Tatzberg 47/48, 01307 Dresden, Germany. Electronic address: simon.alberti@tu-dresden.de.
Publikováno v:
Cell [Cell] 2020 May 14; Vol. 181 (4), pp. 818-831.e19. Date of Electronic Publication: 2020 Apr 30.