Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein.

Autor: Noone, Dylan P., Isendoorn, Marjolein M. E., Hamers, Sebastiaan M. W. R., Keizer, Mariska E., Wulffelé, Jip, van der Velden, Tijn T., Dijkstra, Douwe J., Trouw, Leendert A., Filippov, Dmitri V., Sharp, Thomas H.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 9/10/2024, Vol. 121 Issue 37, p1-11, 32p

Mono-Palmitoyl-N-Alkylurea Ligands as Specific Activators of Human Toll-Like Receptor 2/6 Heterodimer.

Autor: Isendoorn MME; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden The, Netherlands., Castello G; Department of Immunology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden The, Netherlands., Koç Ç; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden The, Netherlands., Meeuwenoord N; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden The, Netherlands., Codée JDC; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden The, Netherlands., Ossendorp F; Department of Immunology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden The, Netherlands., Filippov DV; Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden The, Netherlands.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Oct 09, pp. e202400583. Date of Electronic Publication: 2024 Oct 09.