Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Iseline Cardon"'
Autor:
Julian Triebelhorn, Iseline Cardon, Kerstin Kuffner, Stefanie Bader, Tatjana Jahner, Katrin Meindl, Tanja Rothhammer-Hampl, Markus J. Riemenschneider, Konstantin Drexler, Mark Berneburg, Caroline Nothdurfter, André Manook, Christoph Brochhausen, Thomas C. Baghai, Sven Hilbert, Rainer Rupprecht, Vladimir M. Milenkovic, Christian H. Wetzel
BACKGROUND: The molecular pathomechanisms of major depressive disorder (MDD) are still not completely understood. Here, we follow the hypothesis, that mitochondrial dysfunction which is inevitably associated with bioenergetic misbalance is a risk fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c668ba319bcaae990223ea981975d7
https://epub.uni-regensburg.de/52492/
https://epub.uni-regensburg.de/52492/
Autor:
Iseline Cardon, Liisa Vesa, Plinio C. Casarotto, Rafael Moliner, Tanja Maritzen, Senem Merve Fred, Cecilia A. Brunello, Markku Varjosalo, Eero Castrén, Liina Laukkanen, Helka Göös
Publikováno v:
J Biol Chem
Several antidepressant drugs activate tropomyosin-related kinase B (TRKB) receptor, but it remains unclear whether these compounds employ a common mechanism for TRKB activation. Here, using MS, we found that a single intraperitoneal injection of fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fb570f93c54b3b8efb2c23e4019c80
http://hdl.handle.net/10138/313776
http://hdl.handle.net/10138/313776
Autor:
Eero Castrén, Cassiano R.A.F. Diniz, Stefan Vestring, Timo Petteri Piepponen, Rafael Moliner, Mart Saarma, Anna Steinzeig, Sudarshan Patil, Giray Enkavi, Mykhailo Girych, Clive R. Bramham, Tsvetan Serchov, Katja Kaurinkoski, Plinio C. Casarotto, Madhusmita Pryiadrashini Sahu, Ilpo Vattulainen, Claus Normann, Cecilia A. Brunello, Hanna Antila, Liina Laukkanen, Sari E. Lauri, Cecilia Cannarozzo, Caroline Biojone, Tomasz Róg, Frederike Winkel, Iseline Cardon, Vera Kovaleva, Senem Merve Fred
Publikováno v:
Cell
bioRxiv
bioRxiv
Summary It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase receptor 2 (TRKB), the brain-derived neurotrophic factor (BDNF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cec48445321f548ec8d7d0cbb51b41
https://doi.org/10.1101/757989
https://doi.org/10.1101/757989
Autor:
Senem Merve Fred, Liina Laukkanen, Cecilia A Brunello, Liisa Vesa, Helka Goos, Iseline Cardon, Rafael Moliner, Tanja Maritzen, Markku Varjosalo, Plinio C Casarotto, Eero Castrén
The activation of TRKB (tropomyosin-related kinase B), the receptor for brain-derived neurotrophic factor (BDNF), is a crucial step in brain plasticity. Several antidepressant drugs are reported to activate TRKB, and animals with compromised BDNF or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8f441abdb699370914dee823d7e816