Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Isao Araki"'
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/aac5ebfa4eb64d02ae5cfe6980a08543
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
We conducted this study to examine whether acid-sensing ion channels (ASICs) are involved in the modulation of urinary bladder activity with or without intravesical irritation induced by acetic acid. All in vivo evaluations were conducted during cont
Externí odkaz:
https://doaj.org/article/83f823fd104c4ba8a76401d525f3f24d
Autor:
Akira Yoshida, Shiori Kuraoka, Yoshihiko Ito, Takashi Okura, Yoshiharu Deguchi, Atsushi Otsuka, Seiichiro Ozono, Masayuki Takeda, Keisuke Masuyama, Isao Araki, Shizuo Yamada
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 40-46 (2014)
Abstract.: The aim of the current study was to demonstrate highly specific and direct binding activity of tritium ([3H])-labeled imidafenacin for labeling muscarinic receptors in human bladder and parotid gland. Specific binding of [3H]imidafenacin i
Externí odkaz:
https://doaj.org/article/87ba683de5d14a02ba347ed164ec8e17
Autor:
Yusaku Okada, Masayuki Takeda, Shuqi Du, Tsutomu Mochizuki, Hideki Kobayashi, Isao Araki, Mitsuharu Yoshiyama
Publikováno v:
Pharmaceuticals, Vol 3, Iss 7, Pp 2248-2267 (2010)
The expression of multiple ion channels and receptors is essential for nociceptors to detect noxious stimuli of a thermal, mechanical or chemical nature. The peripheral sensory transduction systems of the urinary bladder include sensory nerve endings
Externí odkaz:
https://doaj.org/article/9907419e6c8043318a2e1dbb74ffc9d7
Autor:
Masayuki Takeda, Isao Araki, Tsutomu Mochizuki, Hiroshi Nakagomi, Hideki Kobayashi, Norifumi Sawada, Hidenori Zakohji
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 2, Pp 121-127 (2010)
Normal lower urinary tract function consists of voiding and storage. During voiding, the pontine micturition reflex center orders the sacral parasympathetic nucleus to increase parasympathetic activity, resulting in urinary bladder detrusor contracti
Externí odkaz:
https://doaj.org/article/cd3b6eb3fd084e059e8e5046843bc7bd
Autor:
Hideki Kobayashi, Teruhisa Nomura, Yaburu Haneda, Norifumi Sawada, Isao Araki, Masayuki Takeda
Publikováno v:
Clinics and Practice, Vol 5, Iss 1 (2015)
Congenital prepubic sinus is an extremely rare anomaly. The etiology is uncertain and the anatomical features often differ from each other. We report a 22-year-old woman with a congenital prepubic sinus accompanied by a prevesical abscess. She was ad
Externí odkaz:
https://doaj.org/article/7c7189395898483188dab4a726419c5d
Autor:
Yuki Takahashi, Hideo Tanaka, Yoshitaka Koga, Shunichi Takiguchi, Shigeru Ogimoto, Shizuyo Inaba, Hiroyuki Matsuoka, Yuka Miyajima, Takeshi Takagi, Fujiko Irie, Yoshihito Bamba, Fuyo Yoshimi, Tomoyuki Suzuki, Isao Araki, Chika Shirai, Sayuri Matsumoto, Motoyuki Shimizu, Toshiyuki Shibata, Hitomi Nagai, Masaru Kinoshita, Rie Fujita, Tsuyoshi Ogata
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 20
Issue 4
Pages: 2779
Volume 20
Issue 4
Pages: 2779
To assess temporal changes to the risk of death in COVID-19 cases caused by the Omicron variant, we calculated age-standardized case fatality rates (CFR) in patients aged ≥40 years over nine diagnostic periods (3 January to 28 August 2022) in ten J
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12107-12122 (2013)
Volume 14
Issue 6
Pages 12107-12122
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12107-12122 (2013)
Volume 14
Issue 6
Pages 12107-12122
Eviprostat is a popular phytotherapeutic agent for the treatment of lower urinary tract symptoms (LUTS). At present, the signaling mechanisms underlying its therapeutic effects are still poorly understood. Given that cAMP has been reported to suppres
Publikováno v:
Open Journal of Urology. :47-52
Purpose: Large conductance, voltage- and Ca2+-activated K+ (BK) channel is thought to have a central role to regulate urinary bladder smooth muscle functions, and its dysfunction may lead to increase of urination frequency and overactive bladder. The
Autor:
Isao Araki, Masayuki Takeda, Mizuya Fukasawa, Manabu Kamiyama, Norifumi Sawada, Mitsuharu Yoshiyama, Yoshio Takihana, Hiroshi Nakagomi
Publikováno v:
Open Journal of Urology. :102-109
Background: Cannabinoid receptor subtype 1 (CB1) has a relationship to the proliferation of various cells including malignant tumoral cells. We investigated and compared the expression of CB1 in benign and malignant human prostate tissues and in beni