Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Isao Hasegawa"'
Autor:
Rizal Ichwansyah, Keigo Onda, Jun Egawa, Takeshi Matsuo, Takafumi Suzuki, Toshiyuki Someya, Isao Hasegawa, Keisuke Kawasaki
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
Animacy perception, the ability to discern living from non-living entities, is crucial for survival and social interaction, as it includes recognizing abstract concepts such as movement, purpose, and intentions. This process involves interpreting cue
Externí odkaz:
https://doaj.org/article/5a4b396cc6ec4e8db3191b2368572983
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundIndividuals with autism spectrum disorder (ASD) exhibit persistent deficits in social interaction and communication in adulthood. Pioneering studies have suggested that these difficulties arise from a lack of immediate, spontaneous mentaliz
Externí odkaz:
https://doaj.org/article/0b82656b78f44526a0e0af6e8fdaf476
Autor:
Naoya Nishioka, Hayato Kawachi, Tadaaki Yamada, Motohiro Tamiya, Yoshiki Negi, Yasuhiro Goto, Akira Nakao, Shinsuke Shiotsu, Keiko Tanimura, Takayuki Takeda, Asuka Okada, Taishi Harada, Koji Date, Yusuke Chihara, Isao Hasegawa, Nobuyo Tamiya, Taiki Masui, Natsuki Sai, Masaki Ishida, Yuki Katayama, Kenji Morimoto, Masahiro Iwasaku, Shinsaku Tokuda, Takashi Kijima, Koichi Takayama
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSeveral studies explored the association between thyroid transcription factor-1 (TTF-1) and the therapeutic efficacy of immunotherapy. However, the effect of TTF-1 on the therapeutic efficacy of programmed death-1 (PD-1) inhibitor/chemoim
Externí odkaz:
https://doaj.org/article/b283d63fa0724718827e2777a8b09bb4
Autor:
Yuki Katayama, MD, PhD, Tadaaki Yamada, MD, PhD, Kenji Morimoto, MD, PhD, Hiroyuki Fujii, MD, Satomi Morita, MD, PhD, Keiko Tanimura, MD, PhD, Takayuki Takeda, MD, PhD, Asuka Okada, MD, PhD, Shinsuke Shiotsu, MD, PhD, Yusuke Chihara, MD, PhD, Osamu Hiranuma, MD, Takahiro Yamada, MD, PhD, Takahiro Ota, MD, PhD, Taishi Harada, MD, Isao Hasegawa, MD, PhD, Masahiro Iwasaku, MD, PhD, Shinsaku Tokuda, MD, PhD, Noriyuki Tanaka, MD, PhD, Aya Miyagawa-Hayashino, MD, PhD, Koichi Takayama, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 3, Pp 100644- (2024)
Introduction: Multiple programmed death-ligand 1 (PD-L1) immunohistochemistry assays performed using different antibodies including DAKO 22C3, DAKO 28-8, and Ventana SP142 PD-L1—predictive markers for response to various immune checkpoint inhibitor
Externí odkaz:
https://doaj.org/article/3964141379334812bbe15faf7291e902
Autor:
Shota Takei, Hayato Kawachi, Tadaaki Yamada, Motohiro Tamiya, Yoshiki Negi, Yasuhiro Goto, Akira Nakao, Shinsuke Shiotsu, Keiko Tanimura, Takayuki Takeda, Asuka Okada, Taishi Harada, Koji Date, Yusuke Chihara, Isao Hasegawa, Nobuyo Tamiya, Yuki Katayama, Naoya Nishioka, Kenji Morimoto, Masahiro Iwasaku, Shinsaku Tokuda, Takashi Kijima, Koichi Takayama
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe proportion of older patients diagnosed with advanced-stage non-small cell lung cancer (NSCLC) has been increasing. Immune checkpoint inhibitor (ICI) monotherapy (MONO) and combination therapy of ICI and chemotherapy (COMBO) are standa
Externí odkaz:
https://doaj.org/article/0523905fe5d04548b83c0aeba67c60f5
Autor:
Yosuke Muranaka, Taisuke Maki, Isao Hasegawa, Hiroyuki Nakagawa, Ryutaro Kubota, Ryoma Kaji, Kazuhiro Mae
Publikováno v:
Journal of Chemical Engineering of Japan, Vol 56, Iss 1 (2023)
The synthesis of fatty acid methyl ester from soybean oil was examined. A microreactor was used as a reactor, and the results were compared with those by batch reaction. In a batch reaction experiment, the concentration of by-product glycerol was lar
Externí odkaz:
https://doaj.org/article/e20540bdef8b4b44b9bdd42f274658b4
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113169- (2023)
Summary: Interaction between the inferotemporal (ITC) and prefrontal (PFC) cortices is critical for retrieving information from memory and maintaining it in working memory. Neural oscillations provide a mechanism for communication between brain regio
Externí odkaz:
https://doaj.org/article/923f2eab1be44a22b572f4a0932e7722
Autor:
Yuki Katayama, MD, Tadaaki Yamada, MD, PhD, Kenji Morimoto, MD, PhD, Hiroyuki Fujii, MD, Satomi Morita, MD, Keiko Tanimura, MD, PhD, Takayuki Takeda, MD, PhD, Asuka Okada, MD, PhD, Shinsuke Shiotsu, MD, PhD, Yusuke Chihara, MD, PhD, Osamu Hiranuma, MD, Takahiro Yamada, MD, PhD, Takahiro Ota, MD, PhD, Taishi Harada, MD, Isao Hasegawa, MD, PhD, Akihiro Yoshimura, MD, PhD, Masahiro Iwasaku, MD, PhD, Shinsaku Tokuda, MD, PhD, Young Hak Kim, MD, PhD, Koichi Takayama, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 4, Pp 100494- (2023)
Introduction: Lung adenocarcinoma with negative TTF-1 expression is believed to be a poor prognostic factor for certain systemic treatments. Nevertheless, the impact of TTF-1 expression on combined chemoimmunotherapy remains unclear. We aimed to inve
Externí odkaz:
https://doaj.org/article/f5a29b79c158468da31bfa4f00a93ada
Autor:
Nanxi Liu, Atsuhiko Iijima, Yutaka Iwata, Kento Ohashi, Nobuyoshi Fujisawa, Toshikuni Sasaoka, Isao Hasegawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract When writing an object’s name, humans mentally construct its spelling. This capacity critically depends on use of the dual-structured linguistic system, in which meaningful words are represented by combinations of meaningless letters. Here
Externí odkaz:
https://doaj.org/article/875028724bf644faad677970e17b3bff
Autor:
Shinsuke Shiotsu, Akihiro Yoshimura, Tadaaki Yamada, Kenji Morimoto, Michiko Tsuchiya, Hiroshige Yoshioka, Osamu Hiranuma, Yusuke Chihara, Takahiro Yamada, Isao Hasegawa, Takahiro Ohta, Takayuki Takeda, Noriya Hiraoka, Koichi Takayama
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesWe investigated the efficacy and safety of pembrolizumab monotherapy as first-line treatment for poor Eastern Cooperative Oncology Group performance status (PS) and elderly patients with programmed cell death-ligand 1 (PD-L1)-positive advan
Externí odkaz:
https://doaj.org/article/70e4a1568c644994b748777d7b9b5168