Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Isao, Takata"'
Publikováno v:
Japanese Journal of Pharmacology. 78:225-228
This study demonstrated the decrease of bone mineral density (BMD) in the type II collagen (CII)-induced arthritis (CIA) model in rats and the relationship between BMD and paw edema and the effect of dexamethasone-21-phosphate (DEX). The paw swelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169878ed40b6c13d23a8b2b474810334
https://doi.org/10.1254/jjp.78.225
https://doi.org/10.1254/jjp.78.225
Publikováno v:
Clinical Immunology and Immunopathology. 84:166-170
This study demonstrates that systemic and local decreases in bone mineral density (BMD) occurred with Freund's complete adjuvant injection in the rat right footpad using dual energy X-ray absorptiometry. The rats were assigned to either adjuvant-trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c7c57a78c4c9913748b7768623ff28
https://doi.org/10.1006/clin.1997.4373
https://doi.org/10.1006/clin.1997.4373
Publikováno v:
Experimental Animals. 46:165-169
The effects of anti-rheumatic drugs (dexamethasone 0.1 mg/kg and naproxen 5 mg/kg) were evaluated immunologically and histopathologically on type II collagen-induced arthritis in Lewis rats. Increased paw volume in the hind limbs was significantly su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3853077f7954e9a39292ab2764e1c271
https://doi.org/10.1538/expanim.46.165
https://doi.org/10.1538/expanim.46.165
Publikováno v:
Experimental Animals. 44:63-66
11Lewis rats were immunized with an intradermal injection of type II collagen to study the time course of arthritic lesions. Serum type II collagen antibody was detected 9 days after immunization. Increased paw volume in the hind limbs was noted on d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e13cac24e6ecbc89a61d469389c834
https://doi.org/10.1538/expanim.44.63
https://doi.org/10.1538/expanim.44.63
Publikováno v:
International Journal of Immunopharmacology. 15:469-476
Interleukin 6 (IL-6) is a multifunctional cytokine and plays an important role in host defense mechanisms. Enhanced production of IL-6 has been reported in polyclonal B-cell abnormalities and autoimmune diseases such as rheumatoid arthritis (RA). To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669225efc227c65f6df0a7ccefc8f2bf
https://doi.org/10.1016/0192-0561(93)90061-3
https://doi.org/10.1016/0192-0561(93)90061-3
Autor:
Isao Takata, Toshiki Takagi, Takashi Murata, Tatsuo Suzuki, Ryuichi Totsuka, Hisako Fujimura, Yasushi Ohmachi, Peter W. Tsao
Publikováno v:
Clinical immunology and immunopathology. 83(2)
The transcription factor NF-kappa B plays a significant role in inflammatory diseases. In this study we have investigated the expression of activated NF-kappa B p65 subunit in the rat adjuvant arthritis model in a 28-day time-course experiment using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c34a9c70630d3d59a498f0ef6e337f
https://pubmed.ncbi.nlm.nih.gov/9143378
https://pubmed.ncbi.nlm.nih.gov/9143378
Autor:
Isao Takata
Publikováno v:
Hiroshima Math. J. 27, no. 1 (1997), 149-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b6d50fe7a711f07e96f24976bd4b2e
http://projecteuclid.org/euclid.hmj/1206127142
http://projecteuclid.org/euclid.hmj/1206127142
Publikováno v:
International journal of immunopharmacology. 17(7)
The effects of TA-383 (0.016, 0.08, 0.4, 2 and 10 mg/kg) and anti-rheumatic drugs (lobenzarit 10 and 50 mg/kg, dexamethasone 0.25 mg/kg) were evaluated on type II collagen-induced arthritis in DBA/1J mice. The arthritis score was markedly suppressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172209f5f5617435da459f47ee120c85
https://pubmed.ncbi.nlm.nih.gov/8586488
https://pubmed.ncbi.nlm.nih.gov/8586488
Autor:
Azusa Okaniwa, Hiromi Hinoue, Isao Takata, Tadashi Sato, Makoto Ueno, Yoshio Minato, Masakazu Takeshita, Kazunori Imaizumi
Publikováno v:
Jikken dobutsu. Experimental animals. 43(1)
Eight male DBA/1J mice immunized twice by intradermal injection of type II collagen were autopsied 12 weeks after the first immunization and analyzed for anti-type II collagen antibody level, and the limb joints were examined radiologically and histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ac6bac28cd8d9c2209b9696d0723a2
https://pubmed.ncbi.nlm.nih.gov/8119330
https://pubmed.ncbi.nlm.nih.gov/8119330
Publikováno v:
International journal of immunopharmacology. 15(4)
We have evaluated the effect of a novel anti-rheumatic drug, cis -2-(4-chlorophenyl)-4, 5-diphenyl-2-imidazoline hydrochloride (TA-383), on type II collagen (CII)-induced arthritis in DBA/1J mice. Treatment with TA-383 (0.4 mg/kg/day) from the day of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2458f551d7041735eb33b65efe89ab1f
https://pubmed.ncbi.nlm.nih.gov/8365826
https://pubmed.ncbi.nlm.nih.gov/8365826