Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Isamu Matsuda"'
Autor:
Mohammad Jafar Tehrani, Isamu Matsuda, Atsushi Yamagata, Yu Kodama, Tatsuya Matsunaga, Mayuko Sato, Kiminori Toyooka, Dan McElheny, Naohiro Kobayashi, Mikako Shirouzu, Yoshitaka Ishii
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Arctic (E22G) mutation in amyloid-β (Aβ enhances Aβ40 fibril accumulation in Alzheimer’s disease (AD). Unlike sporadic AD, familial AD (FAD) patients with the mutation exhibit more Aβ40 in the plaque core. However, structural details o
Externí odkaz:
https://doaj.org/article/2718d8d208dd48aca1047b76fa924bdd
Autor:
Isamu Matsuda, Suwa Katsunori, Kenta Aoki, Kazuhito Harada, Jun Mizukami, Sumiaki Fukuda, Sho Kadowaki, Takashi Inaba, Takashi Watanabe, Yoshitoshi Kodama, Shinji Yata, Yasuhiro Oe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:1228-1233
Exploration of alternative structures of the substituted piperidine or piperazine ring which are characteristic in most of the reported GPR119 agonists provided novel spirocyclic cyclohexane derivatives. The representative 17 with a high three-dimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b6294d0af2043cb0f11fc589e6c54
https://doi.org/10.1016/j.bmcl.2018.02.044
https://doi.org/10.1016/j.bmcl.2018.02.044
Autor:
Yuji Ishii, Isamu Matsuda, Takahiro Nemoto, Takayuki Kamihara, Yoshitaka Ishii, Yuki Endo, Ayesha Wickramasinghe, Yusuke Nishiyama
Publikováno v:
Journal of Magnetic Resonance. 286:99-109
Proton-detected solid-state NMR (SSNMR) spectroscopy has attracted much attention due to its excellent sensitivity and effectiveness in the analysis of trace amounts of amyloid proteins and other important biological systems. In this perspective arti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b69645cd937da724448966914759d64
https://doi.org/10.1016/j.jmr.2017.11.011
https://doi.org/10.1016/j.jmr.2017.11.011
Publikováno v:
J Biol Chem
Increasing evidence highlights the central role of neurotoxic oligomers of the 42-residue-long β-amyloid (Aβ42) in Alzheimer's disease (AD). However, very limited information is available on the structural transition from oligomer to fibril, partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516870491858f9a8b150e302a9271b52
https://pubmed.ncbi.nlm.nih.gov/31771980
https://pubmed.ncbi.nlm.nih.gov/31771980
Publikováno v:
Journal of Biomolecular NMR. 64:131-141
This study demonstrates a novel spectral editing technique for protein solid-state NMR (SSNMR) to simplify the spectrum drastically and to reduce the ambiguity for protein main-chain signal assignments in fast magic-angle-spinning (MAS) conditions at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4daf6f7a29dc88451ddd44e76ee3b28a
https://doi.org/10.1007/s10858-016-0014-4
https://doi.org/10.1007/s10858-016-0014-4
Publikováno v:
Journal of Magnetic Resonance. 322:106857
Ultra-fast magic-angle spinning (UFMAS) at a MAS rate (ωR/2π) of 60 kHz or higher has dramatically improved the resolution and sensitivity of solid-state NMR (SSNMR). However, limited polarization transfer efficiency using cross-polarization (CP) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994e9cffcf3249b4dbef8b12cae4bdc9
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100839312
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100839312
Autor:
Masatsune Kainosho, Yuki Endo, Yiling Xiao, Yoshitaka Ishii, Sudhakar Parthasarathy, Isamu Matsuda, Yusuke Nishiyama, Kazuo Yamauchi, Fei Long, Mitsuhiro Takeda, Tetsuo Asakura, Tsutomu Terauchi, Takahiro Nemoto, Songlin Wang
Publikováno v:
Chemical Communications. 51:15055-15058
We present a 3D (1)H-detected solid-state NMR (SSNMR) approach for main-chain signal assignments of 10-100 nmol of fully protonated proteins using ultra-fast magic-angle spinning (MAS) at ∼80 kHz by a novel spectral-editing method, which permits dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cd95f311e8811b1053ccfd45f24c88
https://doi.org/10.1039/c5cc04618a
https://doi.org/10.1039/c5cc04618a
Autor:
Yiling Xiao1, Isamu Matsuda1,2, Masafumi Inoue3,4, Tomoya Sasahara3,5, Minako Hoshi5,6, Yoshitaka Ishii1,2,7 ishii@bio.titech.ac.jp
Publikováno v:
Journal of Biological Chemistry. 1/10/2020, Vol. 295 Issue 2, p458-467. 10p.
Autor:
Ryuji, Kobayashi, Kimiko, Hirotsu, Kenji, Yabuwaki, Miyuki, Iwata, Yuki, Miyake, Hirochika, Karinaga, Mariko, Kobayashi, Isamu, Matsuda, Department of Occupational Therapy, School of Health Science, KIBI International University, Department of Human Nutrition, Faculty of Human Life Sciences, Yamaguchi Prefectural University, Watanabe Hospital
Publikováno v:
吉備国際大学保健科学部研究紀要 = Journal of Kibi International University School of Health Science. 13:79-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::92e550ec2959bd86e5ce977236174d59
http://id.nii.ac.jp/1320/00000646/
http://id.nii.ac.jp/1320/00000646/
Autor:
Ryuji, Kobayashi, Hideki, Shiraishi, Daisuke, Satoh, Kounosuke, Tomori, Isamu, Matsuda, Kimiko, Hirotsu, Akiko, Takahashi, Ryutaro, Nagatani, Department of Occupational Therapy, School of Health Science, KIBI International University, Department of Occupational Therapy, Ibaraki Prefectural University of Health Sciences, School of Rehabilitation, Faculty of Health and Social Work, Kanagawa University of Human Services, Department of Human Nutrition, Faculty of Human Life Sciences, Yamaguchi Prefectural University, Graduate School of Health Science, KIBI International University
Publikováno v:
吉備国際大学保健科学部研究紀要 = Journal of Kibi International University School of Health Science. 12:91-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::8e4fa328316f6c88b2756695172d6e22
http://id.nii.ac.jp/1320/00000633/
http://id.nii.ac.jp/1320/00000633/