Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Isaline Mees"'
Publikováno v:
Journal of Huntington's Disease. 12:1-13
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder. The disease, characterized by motor, cognitive, and psychiatric impairments, is caused by the expansion of a CAG repeat in the huntingtin gene. Despite the discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::040ef4ac6c54439c771d3cfbcd7c7b62
https://doi.org/10.3233/jhd-230569
https://doi.org/10.3233/jhd-230569
Autor:
Isaline Mees, Harvey Tran, Anne Roberts, Larissa Lago, Shanshan Li, Blaine R. Roberts, Anthony J. Hannan, Thibault Renoir
Publikováno v:
Molecular Neurobiology. 59:2456-2471
Protein phosphorylation plays a role in many important cellular functions such as cellular plasticity, gene expression, and intracellular trafficking. All of these are dysregulated in Huntington's disease (HD), a devastating neurodegenerative disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ac20b56d5449a6bf2721c0391ec35f
https://doi.org/10.1007/s12035-021-02698-y
https://doi.org/10.1007/s12035-021-02698-y
Autor:
Isaline Mees, Shanshan Li, Leah C Beauchamp, Kevin J Barnham, Mathias Dutschmann, Anthony J Hannan, Thibault Renoir
Publikováno v:
Human Molecular Genetics. 31:1997-2009
Tubulin-associated unit (Tau) is a microtubule-associated protein, whose abnormal phosphorylation and deposition in the brain characterizes a range of neurodegenerative diseases called tauopathies. Recent clinical (post-mortem) and pre-clinical evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89d9b96c9af612d407483cd52e67d63
https://doi.org/10.1093/hmg/ddac001
https://doi.org/10.1093/hmg/ddac001
Autor:
Isaline Mees, Shanshan Li, Harvey Tran, Ching-Seng Ang, Nicholas A Williamson, Anthony J Hannan, Thibault Renoir
Publikováno v:
Brain Communications. 4
Huntington’s disease is a fatal autosomal-dominant neurodegenerative disorder, characterized by neuronal cell dysfunction and loss, primarily in the striatum, cortex and hippocampus, causing motor, cognitive and psychiatric impairments. Unfortunate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29beb2ab68a7f1a56fab4764be200f1f
https://doi.org/10.1093/braincomms/fcac305
https://doi.org/10.1093/braincomms/fcac305
Publikováno v:
Degenerative Disorders of the Brain ISBN: 9781351208918
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a935afbd8bdb0a2bd2155b0c92b30bf5
https://doi.org/10.4324/9781351208918-5
https://doi.org/10.4324/9781351208918-5
