Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Isako Sakaguchi"'
Autor:
Audrey J. Gray, Yuko Horikoshi, Yoshihiro Nakajima, Chie Takeyama, Kouhei Nishitomi, Motoko Hosono, Isako Sakaguchi, Paul S. Aisen, Gaku Sakaguchi, Akinobu Ota, Hui Fang Li, Yasuji Matsuoka, Philip C. Wong, Amanda G. Becker, S. Sakura Minami, Chiho Hirata-Fukae, Tsuyoshi Kihara, Akira Kato, Noriaki Kinoshita, Masahiro Maeda
Publikováno v:
Journal of Neurochemistry. 99:1555-1563
Accumulation of amyloid beta peptide (Abeta) in brain is a hallmark of Alzheimer's disease (AD). Inhibition of beta-site amyloid precursor protein (APP)-cleaving enzyme-1 (BACE1), the enzyme that initiates Abeta production, and other Abeta-lowering s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab1d96a723005ea0f5b01279733f7e7
https://doi.org/10.1111/j.1471-4159.2006.04178.x
https://doi.org/10.1111/j.1471-4159.2006.04178.x
Autor:
Azusa Mikami, Hidekuni Yamakawa, Motoko Hosono, Takashi Yutsudo, Shoichi Ishiura, Yoshihiro Nakajima, Naohiro Itoh, Isako Sakaguchi, Ayako Terawaki, Gaku Sakaguchi, Akira Kato, Masahiro Maeda
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd195b33ea2e9f607a69228dc20f64ca
https://doi.org/10.1016/j.jalz.2008.05.595
https://doi.org/10.1016/j.jalz.2008.05.595
Autor:
Gaku Sakaguchi, Yasuji Matsuoka, Tsuyoshi Kihara, Yoshihiro Nakajima, Noriaki Kinoshita, Yuko Horikoshi, Motoko Hosono, Isako Sakaguchi, Kouhei Nishitomi, Akira Kato, Paul S. Aisen
Publikováno v:
Alzheimer's & Dementia. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e20cfdaa4be934b2086a8f4313ed350
https://doi.org/10.1016/j.jalz.2006.05.2004
https://doi.org/10.1016/j.jalz.2006.05.2004
Autor:
Kazuwa Nakao, Kazuyuki Sasakura, Yoshito Numata, Keiichi Imagawa, Kiminori Hosoda, Isako Sakaguchi, Mikio Tamaki, Atsushi Morita, Shino Kikuoka, Hiroshi Teraoka, Goro Katsuura, Tetsuo Tsuji, Yayoi Matumoto, Yoshihiro Ogawa
Publikováno v:
The Journal of biological chemistry. 273(52)
To elucidate the structural requirement of human leptin for its functions, the wild-type, mutant-type, C-terminal deletion, and N-terminal deletion were expressed in Escherichia coli and purified in soluble forms. These leptin analogs were intracereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc41a0b776a3adcc9b04300022eb09f
https://pubmed.ncbi.nlm.nih.gov/9857064
https://pubmed.ncbi.nlm.nih.gov/9857064
Autor:
Toshiya Manabe, Mineto Yokoi, Katsunori Kobayashi, Hitoshi Ohishi, Sakashi Nomura, Ryuichi Shigemoto, Kazuki Nakao, Kenji Nakamura, Tomoyuki Takahashi, Shigetada Nakanishi, Isako Sakaguchi, Motoya Katsuki, Goro Katsuura
Publikováno v:
Science (New York, N.Y.). 273(5275)
Subtype 2 of the metabotropic glutamate receptor (mGluR2) is expressed in the presynaptic elements of hippocampal mossy fiber-CA3 synapses. Knockout mice deficient in mGluR2 showed no histological changes and no alterations in basal synaptic transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66504fa5ff7047585ea248cc02b1a88
https://pubmed.ncbi.nlm.nih.gov/8662555
https://pubmed.ncbi.nlm.nih.gov/8662555
Autor:
Masami Eigyo, Teruo Shiomi, Yuzuru Inoue, Isako Sakaguchi, Chiyomi Ishibashi, Shunji Murata, Kiyotaka Koyabu, Akira Matsushita, Ikuo Adachi, Motohiko Ueda
Publikováno v:
Japanese journal of pharmacology. 65(2)
S-312, S-312-d, but not S-312-l, L-type calcium channel antagonists, showed anticonvulsant effects on the audiogenic tonic convulsions in DBA/2 mice; and their ED50 values were 18.4 (12.8-27.1) mg/kg, p.o. and 15.0 (10.2-23.7) mg/kg, p.o., respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93de976f90a18651cf2253fe0171c86e
https://pubmed.ncbi.nlm.nih.gov/7967231
https://pubmed.ncbi.nlm.nih.gov/7967231
Publikováno v:
Japanese Journal of Pharmacology. 73:211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaf44384a3daf9b768ba2f8c81d64ff0
https://doi.org/10.1016/s0021-5198(19)45346-8
https://doi.org/10.1016/s0021-5198(19)45346-8
Autor:
Teruo Shiomi, Kohji Yoshimura, Haruyuki Shintaku, Isako Sakaguchi, Chiyomi Ishibashi, Masahito Horiuchi, Yukio Takahara, Goro Katsuura
Publikováno v:
Japanese Journal of Pharmacology. 71:239
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74ffed66374daa95f084ed77095d4da8
https://doi.org/10.1016/s0021-5198(19)37195-1
https://doi.org/10.1016/s0021-5198(19)37195-1