Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isaiah Dimery"'
Autor:
Hamid R. Amouzadeh, Isaiah Dimery, Jonathan Werner, Gataree Ngarmchamnanrith, Michael J Engwall, Hugo M. Vargas, Deborah Arrindell
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1296-1304 (2019)
Off-target activities of drug candidates observed during in vitro pharmacological profiling frequently do not translate to adverse events (AEs) in human. This could be because off-target activities do not have functional consequences, are not observe
Externí odkaz:
https://doaj.org/article/56cc11ab4f8a45ae841a6b7a14ff28a5
Autor:
Gataree Ngarmchamnanrith, Isaiah Dimery, Hamid R. Amouzadeh, Jonathan Werner, Michael J. Engwall, Hugo M. Vargas, Deborah Arrindell
Publikováno v:
Translational Oncology, Vol 12, Iss 10, Pp 1296-1304 (2019)
Translational Oncology
Translational Oncology
Off-target activities of drug candidates observed during in vitro pharmacological profiling frequently do not translate to adverse events (AEs) in human. This could be because off-target activities do not have functional consequences, are not observe
Autor:
Sven de Vos, Jacqueline C. Barrientos, Brian Munneke, Franck Morschhauser, Isaiah Dimery, Alina Smith, Peter Martin, Ariela Noy, Stephen C. Smith, Christopher R. Flowers, Catherine Thieblemont, Shachar Peles, Morton Coleman, Robert T. Chen, Graham P. Collins, Shuo Ma, Darrin M. Beaupre
Publikováno v:
Blood. 129:2224-2232
Marginal zone lymphoma (MZL) is a heterogeneous B-cell malignancy for which no standard treatment exists. MZL is frequently linked to chronic infection, which may induce B-cell receptor (BCR) signaling, resulting in aberrant B-cell survival and proli
Autor:
David A. Reardon, Roger E. McLendon, Catherine Wheeler, Mark W. Kieran, B.K. Ahmed Rasheed, Darell D. Bigner, Sith Sathornsumetee, Anderson J. Ryan, Jeremy N. Rich, Ling Wang, Stephen T. Keir, Isaiah Dimery, Henry S. Friedman, Michael W. Graner, Arja Kaipainen, Andrea Laforme
Publikováno v:
Clinical Cancer Research. 11:8145-8157
Purpose: Primary central nervous system (CNS) tumors represent a diverse group of tumor types with heterogeneous molecular mechanisms that underlie their formation and maintenance. CNS tumors depend on angiogenesis and often display increased activit
Autor:
Catherine Thieblemont, Shachar Peles, Morton Coleman, Darrin M. Beaupre, Peter Martin, Sven de Vos, Shuo Ma, Stephen C. Smith, Christopher R. Flowers, Isaiah Dimery, Alina Smith, Robert W. Chen, Franck Morschhauser, Brian Munneke, Ariela Noy, Graham P. Collins
Publikováno v:
Blood. 128:1213-1213
Background: Marginal zone lymphoma (MZL) accounts for approximately 10% of cases of non-Hodgkin's lymphoma (NHL). Rituximab in combination with chemotherapy has substantially improved treatment outcomes, but relapse is common. Although therapies for
Autor:
William P. Tong, Joseph R. Bertino, Mary Welch, Gary K. Schwartz, Leonard B. Saltz, Sandra Endres, David K. Kelsen, Isaiah Dimery, Nancy E. Kemeny
Publikováno v:
Anti-cancer drugs. 15(3)
Our objective was to determine the maximum tolerated dose (MTD) of sequential raltitrexed (Tomudex) and 5-fluorouracil (5-FU) by bolus administration every 3 weeks in patients with advanced colorectal cancer (aCRC) and appendiceal adenocarcinoma. Thi