Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Isadora T, Lape"'
Autor:
Robert Greensmith, Isadora T Lape, Cristian V Riella, Alexander J Schubert, Jakob J Metzger, Anand S Dighe, Xiao Tan, Bernhard Hemmer, Josefine Rau, Sarah Wendlinger, Nora Diederich, Anja Schütz, Leonardo V Riella, Michael M Kaminski
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2619-2637 (2024)
Abstract Detecting genetic variants enables risk factor identification, disease screening, and initiation of preventative therapeutics. However, current methods, relying on hybridization or sequencing, are unsuitable for point-of-care settings. In co
Externí odkaz:
https://doaj.org/article/7d2bcb1444954a0f83178a79d9c91a0b
Autor:
Ayman Al Jurdi, Rodrigo B. Gassen, Thiago J. Borges, Zhabiz Solhjou, Frank E. Hullekes, Isadora T. Lape, Orhan Efe, Areej Alghamdi, Poojan Patel, John Y. Choi, Mostafa T. Mohammed, Brigid Bohan, Vikram Pattanayak, Ivy Rosales, Paolo Cravedi, Camille N. Kotton, Jamil R. Azzi, Leonardo V. Riella
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionStudies have shown reduced antiviral responses in kidney transplant recipients (KTRs) following SARS-CoV-2 mRNA vaccination, but data on post-vaccination alloimmune responses and antiviral responses against the Delta (B.1.617.2) variant a
Externí odkaz:
https://doaj.org/article/aec6cd934a12420cb20e414cf3278f07
Autor:
Thiago J. Borges, Naoka Murakami, Isadora T. Lape, Rodrigo B. Gassen, Kaifeng Liu, Songjie Cai, Joe Daccache, Kassem Safa, Tetsunosuke Shimizu, Shunsuke Ohori, Alison M. Paterson, Paolo Cravedi, Jamil Azzi, Peter T. Sage, Arlene H. Sharpe, Xian C. Li, Leonardo V. Riella
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
The programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway is a potent inhibitory pathway involved in immune regulation and is a potential therapeutic target in transplantation. In this study, we show that overexpression of PD-1 on T cells
Externí odkaz:
https://doaj.org/article/e5c5cdd28c4848f786e0494cfcee2014
Autor:
Ayman Al Jurdi, Rodrigo B. Gassen, Thiago J. Borges, Isadora T. Lape, Leela Morena, Frank Hullekes, Orhan Efe, Camille N. Kotton, Leonardo V. Riella
Publikováno v:
Transplantation. 107:e178-e181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::701e143c490c3a37d4ef79db7bbec8a8
https://doi.org/10.1097/tp.0000000000004582
https://doi.org/10.1097/tp.0000000000004582
Autor:
James Hurley, Johan Skog, Anand Srivastava, Albana B Mihali, Leonardo V. Riella, Karim M. Yatim, Jamil Azzi, Mauricio P. Lima Filho, Bruno T. Aoyama, Juliano B. Alhaddad, Siawosh K. Eskandari, Hazim Allos, James F. Markmann, Kassem Safa, Isadora T. Lape, Vasisht Tadigotla, Anil Chandraker, John Choi, Christine M. Coticchia, Richard N. Formica, Areej Alghamdi, Philip Chu, Rania El Fekih
Publikováno v:
J Am Soc Nephrol
Background Developing a noninvasive clinical test to accurately diagnose kidney allograft rejection is critical to improve allograft outcomes. Urinary exosomes, tiny vesicles released into the urine that carry parent cells' proteins and nucleic acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032813607d4e57c3f13641c68d5bbb5d
https://doi.org/10.1681/asn.2020060850
https://doi.org/10.1681/asn.2020060850
Autor:
Thais Silveira Bueno, Bruna Correa Lopes, Isadora T. Lape, Márcia Regina Loiko, Cristine Cerva, Emily Marques dos Reis, José Eduardo Vargas, Angélica Cavalheiro Bertagnolli, Mário de Menezes Coppola, André Vinícius Andrade Bezerra, Rogério Oliveira Rodrigues, Fabiana Quoos Mayer, Fernanda Bastos Rubin de Bitencourt
Publikováno v:
Molecular Biology Reports. 47:7291-7296
Bovine tuberculosis (bTB) is a zoonotic disease caused by Mycobacterium tuberculosis var. bovis, for which the definitive diagnosis is accomplished by bacterial isolation, which has biosafety issues and requires long time. Thus, diagnostic methods wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20ab4a8cc390c82294de34bb62f4c80
https://doi.org/10.1007/s11033-020-05718-7
https://doi.org/10.1007/s11033-020-05718-7
Autor:
Ayman Al Jurdi, Rodrigo B. Gassen, Thiago J. Borges, Isadora T. Lape, Leela Morena, Orhan Efe, Zhabiz Solhjou, Rania El Fekih, Christa Deban, Brigid Bohan, Vikram Pattanayak, Camille N. Kotton, Jamil R. Azzi, Leonardo V. Riella
Publikováno v:
Kidney international. 101(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26085ef06acece1ee4c5672315921569
https://pubmed.ncbi.nlm.nih.gov/35429496
https://pubmed.ncbi.nlm.nih.gov/35429496
Autor:
Ayman Al Jurdi, Rodrigo B. Gassen, Thiago J. Borges, Isadora T. Lape, Leela Morena, Orhan Efe, Zhabiz Solhjou, Rania El Fekih, Christa Deban, Brigid Bohan, Vikram Pattanayak, Camille N. Kotton, Jamil R. Azzi, Leonardo V. Riella
BackgroundAvailable SARS-CoV-2 vaccines have reduced efficacy against the Omicron variant in immunocompetent individuals. Kidney transplant recipients (KTRs) have diminished antiviral responses to wild-type SARS-CoV-2 after vaccination, and data on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352de5c0f18bbe3ca6730f12b8d3f3ad
https://doi.org/10.1101/2022.01.03.22268649
https://doi.org/10.1101/2022.01.03.22268649
Autor:
Shunsuke Ohori, Tetsunosuke Shimizu, Isadora T Lape, Leonardo V. Riella, Joe Daccache, Jamil Azzi, Thiago J Borges, Paolo Cravedi, Alison M. Paterson, Kassem Safa, Songjie Cai, Arlene H. Sharpe, Rodrigo Benedetti Gassen, Kaifeng Liu, Xian C Li, Naoka Murakami, Peter T. Sage
Publikováno v:
JCI Insight
The programmed death 1/programmed death ligand 1 (PD-1/PD-L1) pathway is a potent inhibitory pathway involved in immune regulation and is a potential therapeutic target in transplantation. In this study, we show that overexpression of PD-1 on T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0f3e5d2520ed1ee4b9bd6e14bd3c33
https://doi.org/10.1172/jci.insight.142909
https://doi.org/10.1172/jci.insight.142909
Autor:
Michael M, Kaminski, Miguel A, Alcantar, Isadora T, Lape, Robert, Greensmith, Allison C, Huske, Jacqueline A, Valeri, Francisco M, Marty, Verena, Klämbt, Jamil, Azzi, Enver, Akalin, Leonardo V, Riella, James J, Collins
Publikováno v:
Nature biomedical engineering. 4(6)
In organ transplantation, infection and rejection are major causes of graft loss. They are linked by the net state of immunosuppression. To diagnose and treat these conditions earlier, and to improve long-term patient outcomes, refined strategies for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9788887dd186593d859377bd5fb4d55
https://pubmed.ncbi.nlm.nih.gov/32284553
https://pubmed.ncbi.nlm.nih.gov/32284553