Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Isadora Lopes Alves"'
Autor:
Lisa Quenon, Lyduine E. Collij, David Vállez Garcia, Isadora Lopes Alves, Thomas Gérard, Vincent Malotaux, Lara Huyghe, Juan Domingo Gispert, Frank Jessen, Pieter Jelle Visser, Anouk den Braber, Craig W. Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S. Luckett, Michael Schöll, Giovanni B. Frisoni, Christopher Buckley, Andrew Stephens, Daniele Altomare, Lisa Ford, Cindy Birck, Anja Mett, Rossella Gismondi, Robin Wolz, Sylke Grootoonk, Richard Manber, Mahnaz Shekari, Renaud Lhommel, Laurence Dricot, Adrian Ivanoiu, Gill Farrar, Frederik Barkhof, Bernard J. Hanseeuw, the AMYPAD Consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associated with cognitive decline in clinically normal (CN) individuals. However, it is less well established whether there is an a
Externí odkaz:
https://doaj.org/article/916789749e284220b7135dd30f36111c
Autor:
Ilse Bader, Ilona Bader, Isadora Lopes Alves, David Vállez García, Bruno Vellas, Bruno Dubois, Mercè Boada, Marta Marquié, Daniele Altomare, Philip Scheltens, Rik Vandenberghe, Bernard Hanseeuw, Michael Schöll, Giovanni B. Frisoni, Frank Jessen, Agneta Nordberg, Miia Kivipelto, Craig W. Ritchie, Oriol Grau-Rivera, José Luis Molinuevo, Lisa Ford, Andrew Stephens, Rossella Gismondi, Juan Domingo Gispert, Gill Farrar, Frederik Barkhof, Pieter Jelle Visser, Lyduine E. Collij, on behalf of the AMYPAD consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The mismatch between the limited availability versus the high demand of participants who are in the pre-dementia phase of Alzheimer’s disease (AD) is a bottleneck for clinical studies in AD. Nevertheless, potential enrollment ba
Externí odkaz:
https://doaj.org/article/53ca117657b04d869c1e2fc37d173899
Autor:
Fiona Heeman, Maqsood Yaqub, Janine Hendriks, Bart N. M. van Berckel, Lyduine E. Collij, Katherine R. Gray, Richard Manber, Robin Wolz, Valentina Garibotto, Catriona Wimberley, Craig Ritchie, Frederik Barkhof, Juan Domingo Gispert, David Vállez García, Isadora Lopes Alves, Adriaan A. Lammertsma, on behalf of the AMYPAD Consortium
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Background Despite its widespread use, the semi-quantitative standardized uptake value ratio (SUVR) may be biased compared with the distribution volume ratio (DVR). This bias may be partially explained by changes in cerebral blood flow (CBF)
Externí odkaz:
https://doaj.org/article/3719a1fba4d443faa2e3f243c084473b
Autor:
Lyduine E. Collij, Gill Farrar, David Valléz García, Ilona Bader, Mahnaz Shekari, Luigi Lorenzini, Hugh Pemberton, Daniele Altomare, Sandra Pla, Mery Loor, Pawel Markiewicz, Maqsood Yaqub, Christopher Buckley, Giovanni B. Frisoni, Agneta Nordberg, Pierre Payoux, Andrew Stephens, Rossella Gismondi, Pieter Jelle Visser, Lisa Ford, Mark Schmidt, Cindy Birck, Jean Georges, Anja Mett, Zuzana Walker, Mercé Boada, Alexander Drzezga, Rik Vandenberghe, Bernard Hanseeuw, Frank Jessen, Michael Schöll, Craig Ritchie, Isadora Lopes Alves, Juan Domingo Gispert, Frederik Barkhof
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
BackgroundAmyloid-β (Aβ) accumulation is considered the earliest pathological change in Alzheimer's disease (AD). The Amyloid Imaging to Prevent Alzheimer's Disease (AMYPAD) consortium is a collaborative European framework across European Federatio
Externí odkaz:
https://doaj.org/article/e7fa1233238f47be9c405a3b15ff6cf3
Autor:
Isadora Lopes Alves, Fiona Heeman, Lyduine E. Collij, Gemma Salvadó, Nelleke Tolboom, Natàlia Vilor-Tejedor, Pawel Markiewicz, Maqsood Yaqub, David Cash, Elizabeth C. Mormino, Philip S. Insel, Ronald Boellaard, Bart N. M. van Berckel, Adriaan A. Lammertsma, Frederik Barkhof, Juan Domingo Gispert
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if an
Externí odkaz:
https://doaj.org/article/082c31a7af464c6799346086b3dce7a1
Autor:
Fiona Heeman, Janine Hendriks, Isadora Lopes Alves, Rik Ossenkoppele, Nelleke Tolboom, Bart N. M. van Berckel, Adriaan A. Lammertsma, Maqsood Yaqub, on behalf of the AMYPAD Consortium
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background The standard reference region (RR) for amyloid-beta (Aβ) PET studies is the cerebellar grey matter (GMCB), while alternative RRs have mostly been utilized without prior validation against the gold standard. This study compared fi
Externí odkaz:
https://doaj.org/article/6e49eec9ede4442699b126a1c7216d1a
Autor:
Fiona Heeman, Maqsood Yaqub, Janine Hendriks, Ilona Bader, Frederik Barkhof, Juan Domingo Gispert, Bart N.M. van Berckel, Isadora Lopes Alves, Adriaan A. Lammertsma
Publikováno v:
NeuroImage, Vol 234, Iss , Pp 117953- (2021)
Optimal pharmacokinetic models for quantifying amyloid beta (Aβ) burden using both [18F]flutemetamol and [18F]florbetaben scans have previously been identified at a region of interest (ROI) level. The purpose of this study was to determine optimal q
Externí odkaz:
https://doaj.org/article/e30de19703cd4eb98204dc5f611e21ee
Autor:
Pawel J. Markiewicz, Julian C. Matthews, John Ashburner, David M. Cash, David L. Thomas, Enrico De Vita, Anna Barnes, M. Jorge Cardoso, Marc Modat, Richard Brown, Kris Thielemans, Casper da Costa-Luis, Isadora Lopes Alves, Juan Domingo Gispert, Mark E. Schmidt, Paul Marsden, Alexander Hammers, Sebastien Ourselin, Frederik Barkhof
Publikováno v:
NeuroImage, Vol 232, Iss , Pp 117821- (2021)
Accurate regional brain quantitative PET measurements, particularly when using partial volume correction, rely on robust image registration between PET and MR images. We argue here that the precision, and hence the uncertainty, of MR-PET image regist
Externí odkaz:
https://doaj.org/article/927d5c4df2d64780bd6c99b19e604971
Autor:
Fiona Heeman, Maqsood Yaqub, Isadora Lopes Alves, Kerstin Heurling, Johannes Berkhof, Juan Domingo Gispert, Santiago Bullich, Christopher Foley, Adriaan A. Lammertsma, on behalf of the AMYPAD Consortium
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Background A long dynamic scanning protocol may be required to accurately measure longitudinal changes in amyloid load. However, such a protocol results in a lower patient comfort and scanning efficiency compared to static scans. A compromis
Externí odkaz:
https://doaj.org/article/171773ec862e4ee3a9f43edf0d3cedc8
Autor:
Lyduine E. Collij, Sophie E. Mastenbroek, Gemma Salvadó, Alle Meije Wink, Pieter Jelle Visser, Frederik Barkhof, Bart. N.M. vanBerckel, Isadora Lopes Alves
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The value of quantitative longitudinal and regional amyloid beta (Aβ) measurements in predicting cognitive decline in initially cognitively unimpaired (CU) individuals remains to be determined. Methods We selected 133 CU indivi
Externí odkaz:
https://doaj.org/article/6c1219d13eda4bbfbf632255370a8561