Pharmacological fatty acid synthase inhibitors differently affect the malignant phenotype of oral cancer cells

Autor: Willian Peter Boelcke, Isadora Ferrari Teixeira, Iara Gonçalves Aquino, Amanda Ramos Mazzaro, Florence Juana Maria Cuadra-Zelaya, Ana Paula de Souza, Tuula Salo, Ricardo Della Coletta, Edgard Graner, Débora Campanella Bastos

Objective: Fatty acid synthase levels are associated with aggressiveness, prognosis, and risk of metastasis in oral squamous cell carcinomas. This enzyme contains seven catalytic domains and its inhibition by synthetic or natural drugs has antineopla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e37a1cd38ae397b6da4b2b1d5da5019
http://hdl.handle.net/10138/352827

Standardization of the orthotopic model of tongue SCC and evaluation of the effects of the orlistat/paclitaxel association in relation to metastatic dissemination and tumoral progression

Autor: Isadora Ferrari Teixeira

Publikováno v: Biblioteca Digital de Teses e Dissertações da Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP

Orientadores: Edgard Graner, Débora Campanella Bastos Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba Resumo: O carcinoma de células escamosas (CCE) oral é de grande relevância em saúde públi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dc289384b790bbe53c8c02146a7764

HEAD AND NECK AMYLOIDOSIS AS THE FIRST MANIFESTATION OF MULTIPLE MYELOMA—A CASE REPORT

Autor: Isadora Ferrari Teixeira, Natália Rangel Palmier, Pablo Agustin Vargas, Alan Roger Santos-Silva, Jéssica Montenegro Fonsêca, Paola Aristizabal Arboleda, Márcio Ajudarte Lopes

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e104-e105

A 76-year-old man with medical history of anemia was referred for clinical investigation of hoarseness and dysphagia over the last 2 years. Extraoral head and neck examination revealed diffuse hardened skin. Intraoral examination revealed macroglossi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3596fd321c14095ca67906a5b1167b2
https://doi.org/10.1016/j.oooo.2019.06.444

COMPARISON OF THE EFFECTS OF DIFFERENT FATTY ACID SYNTHASE INHIBITORS ON THE CELL CYCLE, APOPTOSIS, AND MORPHOLOGY OF SQUAMOUS CELL CARCINOMA 9 CELLS

Autor: Edgard Graner, Willian Peter Boelcke, Isadora Ferrari Teixeira, Débora Campanella Bastos, Ricardo D. Coletta

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 129:e133

The aim of this study was to compare the effect of pharmacologic inhibition of 3 different catalytic domains of fatty acid synthase (FASN) on the cell cycle and apoptosis and associate with the morphologic alterations in squamous cell carcinoma 9 (SC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0209a67fba394e5c8556f6f9d787999
https://doi.org/10.1016/j.oooo.2019.06.580