Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isabelle Tran"'
Publikováno v:
Innovation in Aging. 6:82-82
Women generally have higher prevalence of disability than men in later life. Moreover, Blacks and Hispanics usually have higher prevalence of disability than Whites. Little is known about the impact of gender on the association between race and disab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a79801858b45e8e89a893b10586e56f
https://doi.org/10.1093/geroni/igac059.329
https://doi.org/10.1093/geroni/igac059.329
Autor:
Lisa R. Thompson, Dafydd R. Owen, Tim Young, Isabelle Tran, Martin Paul Edwards, Michelle F. Tutt, Ana Monica Correia, Val A. Horne, Thomas Ryckmans
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:4406-4409
A series of libraries were designed using the 1-(cyclopropylmethyl)-2-alkyl-4,5,6,7-tetrahydro-1 H -imidazo[4,5- c ]pyridin-5-ium templates 2a – b , and Sulfonamide derivatives 11a – n proved to be potent agonists of the CB 2 receptor. Analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45612526872047a270414b7c175e3402
https://doi.org/10.1016/j.bmcl.2009.05.062
https://doi.org/10.1016/j.bmcl.2009.05.062
Autor:
Mark L. Lewis, Kana Kon-I, Dafydd R. Owen, Tim Young, Mifune Takeuchi, Isabelle Tran, Miyako Matsumizu, Denise Harding, Helen J. Mason, Christine Anne Louise Watson, Akiko Shima, Margarita Rodriguez-Lens, Takasuke Mukaiyama
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(14)
A series of benzimidazole CB2 receptor agonists were prepared and their properties investigated. Optimisation of the three benzimidazole substituents led to the identification of compound 23, a potent CB2 full agonist (EC50 2.7 nM) with excellent sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78b1de06a8c469259fb60e4fb75e775
https://pubmed.ncbi.nlm.nih.gov/21669533
https://pubmed.ncbi.nlm.nih.gov/21669533
Autor:
Charles E. Mowbray, Rob Webster, Simon Gayton, Anthony Wood, Manos Perros, Matthew D. Selby, Isabelle Tran, Romuald Corbau, Stupple Paul Anthony, Catherine Burt, David Price, Faye J. Quinton, Michael Hawes
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(20)
We prepared three discreet cohorts of potent non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) based on the recently reported 3-cyanophenoxypyrazole lead 3. Several of these compounds displayed very promising anti-HIV activity in vitro, sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16cfe3504dce023c44ac6d7739b403a0
https://pubmed.ncbi.nlm.nih.gov/19748778
https://pubmed.ncbi.nlm.nih.gov/19748778
Autor:
Charles E. Mowbray, Anthony Wood, Manos Perros, Romuald Corbau, Stupple Paul Anthony, Catherine Burt, Rob Webster, Isabelle Tran
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(19)
The design and synthesis of a novel series of non-nucleoside HIV reverse transcriptase inhibitors (NNRTIs) based on a pyrazole template is described. These compounds are active against wild type reverse transcriptase (RT) and retain activity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae5c45485d496c3861bcd3d4f846411
https://pubmed.ncbi.nlm.nih.gov/19709880
https://pubmed.ncbi.nlm.nih.gov/19709880
Autor:
Jean Herscovici, Nathalie Mignet, Michel Bessodes, Jeanne Leblond, Isabelle Tranchant, Daniel Scherman, Marie Breton
Publikováno v:
Pharmaceuticals, Vol 4, Iss 10, Pp 1381-1399 (2011)
Non-viral gene therapy requires innovative strategies to achieve higher transfection efficacy. A few years ago, our group proposed bioinspired lipids whoseinteraction with DNA was not based on ionic interactions, but on hydrogen bonds. We thusdevelop
Externí odkaz:
https://doaj.org/article/e8209e6c0724456d87c0795b71e0e728