Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Isabelle Thome"'
Publikováno v:
Chemistry - A European Journal. 21:7705-7708
A highly stereoselective vinylogous Mukaiyama Michael reaction (VMMR) leading to α-keto phosphonate-containing γ-butenolides with two stereogenic centers is described. The presented transformation is catalyzed by a combination of a commercially ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521b1aba3a512114210cfb9be305436a
https://doi.org/10.1002/chem.201500861
https://doi.org/10.1002/chem.201500861
Publikováno v:
Journal of the American Chemical Society
A simple method for direct C-H imidation is reported using a new perester-based self-immolating reagent and a base-metal catalyst. The succinimide products obtained can be easily deprotected in situ (if desired) to reveal the corresponding anilines d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef31248e652e5dddeb967469d1961fe9
https://doi.org/10.1021/ja501879c
https://doi.org/10.1021/ja501879c
Publikováno v:
Chemistry - A European Journal. 20:1691-1700
A procedure that enables high yielding access to phosphonic γ-(hydroxyalkyl)butenolides with excellent regio-, diastereo- and enantiocontrol is reported. The simultaneous construction of up to two adjacent quaternary stereogenic centers by a catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba7e37d915462770182b61a4b8788e5
https://doi.org/10.1002/chem.201304331
https://doi.org/10.1002/chem.201304331
Autor:
Seok Hwan Kim, Isabelle Thome, Duanteng Chen, Astrid Beyer, Julien Bonnamour, Carsten Bolm, Sukbok Chang, Yu Yuan, Erik Zuidema
Publikováno v:
Advanced Synthesis & Catalysis. 352:2892-2898
Potassium hydroxide (KOH) in dimethyl sulfoxide (DMSO) forms a superbasic medium that allows one to access cross-coupling products from reactions between aryl halides with various sulfur-, oxygen- and nitrogen-based nucleophiles under transition meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b0d3b33adb7a5874733e7a73985d42e
https://doi.org/10.1002/adsc.201000575
https://doi.org/10.1002/adsc.201000575
Publikováno v:
ChemInform. 46
A highly stereoselective vinylogous Mukaiyama Michael reaction (VMMR) leading to α-keto phosphonate-containing γ-butenolides with two stereogenic centers is described. The presented transformation is catalyzed by a combination of a commercially ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78077d6e93586975e196e8a22b740de6
https://doi.org/10.1002/chin.201542025
https://doi.org/10.1002/chin.201542025
Publikováno v:
ChemInform. 45
A new perester-based self-immolating reagent in combination with a base-metal catalyst allows for direct C-H imidation of (hetero)arenes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22738ec1e217922e50cbd92cfe5b79a3
https://doi.org/10.1002/chin.201441043
https://doi.org/10.1002/chin.201441043
Publikováno v:
ChemInform. 45
A highly regio- and stereoselective vinylogous Mukaiyama aldol reaction of α-keto phosphonates and heterocyclic dienol silanes is developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba33100630b7094f167a3005dab9e92
https://doi.org/10.1002/chin.201430188
https://doi.org/10.1002/chin.201430188
Publikováno v:
ChemInform. 44
cules. For the synthesis of N-heterocyclic compounds, CN coupling reactions are highly valuable; consequently, they have quite frequently been used in the preparation of specific polymers, dyes, and biologically active molecules to be used as agroche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20e3b3cb6a31c0a78ff781e3888eea50
https://doi.org/10.1002/chin.201349138
https://doi.org/10.1002/chin.201349138
Publikováno v:
Angewandte Chemie (International ed. in English). 52(29)
cules. For the synthesis of N-heterocyclic compounds, CN coupling reactions are highly valuable; consequently, they have quite frequently been used in the preparation of specific polymers, dyes, and biologically active molecules to be used as agroche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee61357d7ae6f3fa879efc7cd2f7c52
https://pubmed.ncbi.nlm.nih.gov/23740864
https://pubmed.ncbi.nlm.nih.gov/23740864
Autor:
Stephan Bachmann, Hans Iding, Christian Lautz, Isabelle Thomé-Pfeiffer, Caroline Maierhofer, Régis Mondière, Christoph Strasser, Thomas Bär, André Aebi, Andre Schuster, Philipp Schmidt
Publikováno v:
CHIMIA, Vol 75, Iss 7/8, Pp 605-613 (2021)
Ipatasertib is a potent small molecule Akt kinase inhibitor currently being tested in Phase III clinical trials for the treatment of metastatic castration-resistant prostate cancer and triple negative metastatic breast cancer. In this paper an overvi
Externí odkaz:
https://doaj.org/article/670ffc3b70804677822b0735a25d1d8b