Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Isabelle Tardivel"'
Autor:
Claire, Briet, Gwladys, Bourdenet, Ute C, Rogner, Chantal, Becourt, Isabelle, Tardivel, Laurent, Drouot, Christophe, Arnoult, Jean-Claude, do Rego, Nicolas, Prevot, Charbel, Massaad, Olivier, Boyer, Christian, Boitard
Publikováno v:
Frontiers in Immunology
Abrogation of ICOS/ICOS ligand (ICOSL) costimulation prevents the onset of diabetes in the non-obese diabetic (NOD) mouse but, remarkably, yields to the development of a spontaneous autoimmune neuromyopathy. At the pathological level, ICOSL−/− NO
Autor:
Joëlle Morin, Tak W. Mak, Edwige Roy, Claire Briet, Isabelle Tardivel, Anna Tafuri, Hans Lassmann, Nicolas Prevot, Christian Boitard
Publikováno v:
European Journal of Immunology. 40:2267-2276
NOD mice spontaneously develop insulin-dependent diabetes around 10-40 wk of age. Numerous immune gene variants contribute to the autoimmune process. However, genes that direct the autoimmune response toward β cells remain ill defined. In this study
Autor:
Christian Boitard, Philippe Dupraz, Bernard Thorens, D. Rottembourg, Sandra Cottet, Isabelle Tardivel, Jean-Claude Carel, P. Cattan
Publikováno v:
Diabetologia. 46:504-510
betaTC-tet (H2(k)) is a conditional insulinoma cell line derived from transgenic mice expressing a tetracycline-regulated oncogene. Transgenic expression of several proteins implicated in the apoptotic pathways increase the resistance of betaTC-tet c
Autor:
Chantal Lotton, Christian Boitard, Béatrice Faideau, Bruno Lucas, Isabelle Tardivel, Jean-Claude Carel, John F. Elliott
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(1)
Proinsulin is a key Ag in type 1 diabetes, but the mechanisms regulating proinsulin immune tolerance are unknown. We have shown that preproinsulin-2 gene-deficient mice (proins-2−/−) are intolerant to proinsulin-2. In this study, we analyzed the
Autor:
Myriam Rabaud, Murielle Vigneau-Hermellin, Isabelle Tardivel, Jean-Claude Carel, Michael Holers, L. Vitali
Publikováno v:
Diabetes. 46(5)
To study the effect of expression of a single foreign antigen on the outcome of otherwise compatible mouse islet grafts, we have used transgenic mice expressing the human complement receptor 2 (CR2, CD21, C3d/EBV receptor) on their pancreatic beta-ce
Autor:
Jean Baillet, François Pieri, Isabelle Tardivel, Charles Chany, Italina Cerutti, Michel Brazier, G. Desmet, Philippe Daniel
Publikováno v:
Clinica Chimica Acta. 181:255-263
Considering that butyrate-treated malignant cells can recover in a transitory fashion a non-cancerous phenotype, the authors carried out a pharmacokinetics study of butyric acid injected as sodium or arginine salts for possible antitumor therapies. I
Autor:
Jean-Guy Fournier, Charles Chany, Isabelle Tardivel, O. Robain, Italina Cerutti, Françoise Chany-Fournier
Publikováno v:
Acta neuropathologica. 75(6)
Using in situ hybridization with a cloned DNA probe specific for the VSV G protein, viral RNA was detected and localized in CNS tissue of mice infected i.c. with either wild or ts G 31 VSV mutant. In both cases, brain and spinal cord neurons were the
Autor:
Béatrice Faideau, Jean-Paul Briand, Jacques Jami, Sylviane Muller, Isabelle Tardivel, Jean-Claude Carel, Christian Boitard, Chantal Lotton, Philippe Halbout, John F. Elliott, Patricia Krief
Publikováno v:
ResearcherID
Deciphering mechanisms involved in failure of self tolerance to preproinsulin-2 is a key issue in type 1 diabetes. We used nonautoimmune 129SV/Pas mice lacking preproinsulin-2 to study the immune response to preproinsulin-2. In these mice, a T cell r
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