Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Isabelle Sheridan"'
Autor:
Jayna Raghwani, Rebecca Rose, Isabelle Sheridan, Philippe Lemey, Marc A Suchard, Teresa Santantonio, Patrizia Farci, Paul Klenerman, Oliver G Pybus
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005894 (2016)
The treatment of HCV infection has seen significant progress, particularly since the approval of new direct-acting antiviral drugs. However these clinical achievements have been made despite an incomplete understanding of HCV replication and within-h
Externí odkaz:
https://doaj.org/article/9a07f2c669a440aba4cbcfa027e508e5
Autor:
Isabelle Sheridan, Rebecca Rose, Teresa Santantonio, Oliver G. Pybus, Paul Klenerman, Patrizia Farci, Philippe Lemey, Jayna Raghwani, Marc A. Suchard
Publikováno v:
PLoS pathogens, vol 12, iss 9
PLoS Pathogens, Vol 12, Iss 9, p e1005894 (2016)
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 9, p e1005894 (2016)
PLoS Pathogens
The treatment of HCV infection has seen significant progress, particularly since the approval of new direct-acting antiviral drugs. However these clinical achievements have been made despite an incomplete understanding of HCV replication and within-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a62bee5afe945fe21ff5560cdf7b87
https://ora.ox.ac.uk/objects/uuid:75399da7-1425-496c-aec3-6f0ed08fd3ab
https://ora.ox.ac.uk/objects/uuid:75399da7-1425-496c-aec3-6f0ed08fd3ab
Autor:
Paul N. Newton, Isla Humphreys, Oliver G. Pybus, Philippe Lemey, Rattanaphone Phetsouvanah, Bounkong Syhavong, Eleanor Barnes, Isabelle Sheridan, Peter V. Markov, Rachel Taggart, Ling Lu, Paul Klenerman, Bouachan Rasachak
The hepatitis C virus (HCV), which currently infects an estimated 3% of people worldwide, has been present in some human populations for several centuries, notably HCV genotypes 1 and 2 in West Africa and genotype 6 in Southeast Asia. Here we use new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096dd43deeca9abaa3dfb6fb8885c388
https://doi.org/10.1128/jvi.01501-08
https://doi.org/10.1128/jvi.01501-08
Autor:
Michaela Lucas, Gillian Harcourt, Rodney E. Phillips, Eleanor Barnes, Isabelle Sheridan, Paul Klenerman
Publikováno v:
Journal of Viral Hepatitis. 11:324-331
Cellular immunity plays an important role in the control of persistent virus infections such as hepatitis C virus (HCV). Antiviral CD4(+) T cell responses have been shown to accompany resolution of acute disease and there is also a consistent associa
Autor:
Nina Bhardwaj, Kei Ouchi, Daniel G. Kavanagh, Isabelle Sheridan, Joerg Timm, Thillagavathie Pillay, Michaela Lucas, Georg M. Lauer, Raymond T. Chung, Arthur Y. Kim, Bruce D. Walker, Paul Klenerman, Julian Schulze zur Wiesch, Todd M. Allen, Laura L. Reyor, Rajesh T. Gandhi
Publikováno v:
The Journal of Experimental Medicine
In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8+ cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection.
Autor:
Michael Roggendorf, Dermot Kelleher, Paul Klenerman, Hubert E. Blum, Robert Thimme, Hans Christian Spangenberg, Isabelle Sheridan, Scott M. Ward, Fritz von Weizsäcker, Thomas Killinger, Sergei Viazov, Thomas F. Baumert, Christoph Neumann-Haefelin, N Nazarova, Susan McKiernan, Oliver G. Pybus
Publikováno v:
Hepatology (Baltimore, Md.). 43(3)
Virus-specific CD8+ T cell responses play an important role in the natural course of infection; however, the impact of certain CD8+ T cell responses in determining clinical outcome has not been fully defined. A well-defined cohort of women inoculated
Autor:
Kei Ouchi, Rajesh T. Gandhi, Paul Klenerman, Bin Li, Todd M. Allen, Gláucia Paranhos-Baccalà, Joerg Timm, Michaela Lucas, Deborah Casson, Isabelle Sheridan, Julian Schulze zur Wiesch, Markus Reiser, Raymond T. Chung, Bruce D. Walker, Georg M. Lauer, Arthur Y. Kim, Cheryl L. Day
Publikováno v:
Journal of virology. 79(20)
Multispecific CD8+T-cell responses are thought to be important for the control of acute hepatitis C virus (HCV) infection, but to date little information is actually available on the breadth of responses at early time points. Additionally, the influe
Publikováno v:
Journal of virology. 78(7)
Hepatitis C virus (HCV) persists in the majority of those infected despite host immune responses. Evidence has accrued that selectively fixed mutations in the envelope genes (E1 and E2) are associated with viral persistence, particularly those that o
Autor:
Arthur Y. Kim, Cheryl L. Day, R T Ghandhi, Michaela Lucas, Raymond T. Chung, Kei Ouchi, Georg M. Lauer, Isabelle Sheridan, B Lavender, Deborah Casson, Paul Klenerman, Bruce D. Walker, Markus Reiser
Publikováno v:
Hepatology. 38:354-355