Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Isabelle Sahut‐Barnola"'
Autor:
Damien Dufour, Typhanie Dumontet, Isabelle Sahut-Barnola, Aude Carusi, Méline Onzon, Eric Pussard, James Jr Wilmouth, Julie Olabe, Cécily Lucas, Adrien Levasseur, Christelle Damon-Soubeyrand, Jean-Christophe Pointud, Florence Roucher-Boulez, Igor Tauveron, Guillaume Bossis, Edward T. Yeh, David T. Breault, Pierre Val, Anne-Marie Lefrançois-Martinez, Antoine Martinez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
SUMOylation is a mechanism of posttranslational modification involved in eukaryotic cell homeostasis. Here the authors report that mice unable to control SUMOylation in the adrenal cortex develop a selective defect in glucocorticoid production due to
Externí odkaz:
https://doaj.org/article/94675fdf0b57490d98010c427e95a3d3
Autor:
Jorge Miguel Amaya, Ernst Suidgeest, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Guilhem Pagès, Cécile Keller, Louise van der Weerd, Alberto M. Pereira, Antoine Martinez, Onno C. Meijer
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on health, including metabolic abnormalities, as exemplified in Cushing’s syndrome (CS). Magnetic resonance imaging (MRI) studies have found volumetric changes i
Externí odkaz:
https://doaj.org/article/e596fd4c771e4e17bbc71da6814d87aa
Autor:
Coralie Drelon, Annabel Berthon, Isabelle Sahut-Barnola, Mickaël Mathieu, Typhanie Dumontet, Stéphanie Rodriguez, Marie Batisse-Lignier, Houda Tabbal, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Jean-Christophe Pointud, Celso E. Gomez-Sanchez, Seppo Vainio, Jingdong Shan, Sonia Sacco, Andreas Schedl, Constantine A. Stratakis, Antoine Martinez, Pierre Val
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The adrenal cortex undergoes functional zonation to generate an outer zona glomerulosa (ZG) and inner zona fasciculata (ZF), but how this is regulated at a molecular level is unclear. Here, the authors show that ZG differentiation is stimulated by WN
Externí odkaz:
https://doaj.org/article/47e9d947aff442c7b85b4848141ee1ea
Autor:
Felicia Leccia, Marie Batisse-Lignier, Isabelle Sahut-Barnola, Pierre Val, A-Marie Lefrançois Martinez, Antoine Martinez
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Adrenal cortex tumors are divided into benign forms such as primary hyperplasias and adrenocortical adenomas (ACAs), and malignant forms or adrenocortical carcinomas (ACCs). Primary hyperplasias are rare causes of ACTH-independent hypercortisolism. A
Externí odkaz:
https://doaj.org/article/db45dcbda0384f13ae513694d090eeee
Autor:
Coralie Drelon, Annabel Berthon, Bruno Ragazzon, Frédérique Tissier, Roberto Bandiera, Isabelle Sahut-Barnola, Cyrille de Joussineau, Marie Batisse-Lignier, Anne-Marie Lefrançois-Martinez, Jérôme Bertherat, Antoine Martinez, Pierre Val
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44171 (2012)
Adrenal cortical carcinomas (ACC) are rare but aggressive tumours associated with poor prognosis. The two most frequent alterations in ACC in patients are overexpression of the growth factor IGF2 and constitutive activation of Wnt/β-catenin signalli
Externí odkaz:
https://doaj.org/article/8a5aa1d0e2864f478757abec9540e2e9
Autor:
Isabelle Sahut-Barnola, Cyrille de Joussineau, Pierre Val, Sarah Lambert-Langlais, Christelle Damon, Anne-Marie Lefrançois-Martinez, Jean-Christophe Pointud, Geoffroy Marceau, Vincent Sapin, Frédérique Tissier, Bruno Ragazzon, Jérôme Bertherat, Lawrence S Kirschner, Constantine A Stratakis, Antoine Martinez
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000980 (2010)
Carney complex (CNC) is an inherited neoplasia syndrome with endocrine overactivity. Its most frequent endocrine manifestation is primary pigmented nodular adrenocortical disease (PPNAD), a bilateral adrenocortical hyperplasia causing pituitary-indep
Externí odkaz:
https://doaj.org/article/a48e51e04751405a855b77fc9951dea7
Autor:
Sarah Lambert-Langlais, Jean-Christophe Pointud, Anne-Marie Lefrançois-Martinez, Fanny Volat, Michèle Manin, François Coudoré, Pierre Val, Isabelle Sahut-Barnola, Bruno Ragazzon, Estelle Louiset, Catherine Delarue, Hervé Lefebvre, Yoshihiro Urade, Antoine Martinez
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7309 (2009)
Prostaglandin F(2alpha) (PGF(2alpha)), represses ovarian steroidogenesis and initiates parturition in mammals but its impact on adrenal gland is unknown. Prostaglandins biosynthesis depends on the sequential action of upstream cyclooxygenases (COX) a
Externí odkaz:
https://doaj.org/article/f7ea7cd6f06f4ea7acca0a911bd2f0a6
Autor:
James J. Wilmouth, Julie Olabe, Diana Garcia-Garcia, Cécily Lucas, Rachel Guiton, Florence Roucher-Boulez, Damien Dufour, Christelle Damon-Soubeyrand, Isabelle Sahut-Barnola, Jean-Christophe Pointud, Yoan Renaud, Adrien Levasseur, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val
Publikováno v:
Science Advances
Science Advances, 2022, 8 (41), ⟨10.1126/sciadv.add0422⟩
Science Advances, 2022, 8 (41), ⟨10.1126/sciadv.add0422⟩
SummaryIn contrast with most cancers, adrenocortical carcinomas (ACC) are more frequent in women than men, but the underlying mechanisms of this sexual dimorphism remain elusive. Homozygous deletion of the negative WNT pathway regulator ZNRF3 is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa770a0a84d3d41c96cad1df1fd90a1
https://cnrs.hal.science/hal-03864625
https://cnrs.hal.science/hal-03864625
Autor:
Damien Dufour, Typhanie Dumontet, Isabelle Sahut-Barnola, Meline Onzon, Eric Pussard, Jr James Wilmouth, Julie Olabe, Adrien Levasseur, Guillaume Bossis, Edward Yeh, Pierre Val, Antoine Martinez, Lefrancois-Martinez Anne-Marie
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435674beace2d4d583aa0b4e9742a40d
https://doi.org/10.1530/endoabs.81.oc2.2
https://doi.org/10.1530/endoabs.81.oc2.2
Autor:
Jorge Miguel Amaya, Eva M. G. Viho, Hetty C. M. Sips, Reshma A. Lalai, Isabelle Sahut‐Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Alberto M. Pereira, Antoine Martinez, Onno C. Meijer
Publikováno v:
Journal of Neuroendocrinology
Journal of Neuroendocrinology, 2022, 34 (4), ⟨10.1111/jne.13125⟩
Journal of neuroendocrinology, 34(4):e13125. Wiley-Blackwell
Journal of Neuroendocrinology, 34(4). WILEY
Journal of Neuroendocrinology, 2022, 34 (4), ⟨10.1111/jne.13125⟩
Journal of neuroendocrinology, 34(4):e13125. Wiley-Blackwell
Journal of Neuroendocrinology, 34(4). WILEY
Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme form, Cushing's syndrome, is adequately modelled in the AdKO(2.0) mouse, consequential to adrenocortical hypertrophy and hypercorticosteronemia. We previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23df485f51ad3c28e2f8bb493fa76ec9
https://hal.science/hal-03765716
https://hal.science/hal-03765716