Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Isabelle Marx"'
Autor:
Isabelle Marx
Publikováno v:
Agronomie, environnement et sociétés.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::485e1c534d374cfbe73a51e2ea3d5216
https://doi.org/10.54800/mxa543
https://doi.org/10.54800/mxa543
Autor:
Ana-Maria Navarrete, Jiun-Ruey Hu, Cécile V. Denis, Isabelle Marx, Peter J. Lenting, Paulette Legendre, Olivier D. Christophe, Caterina Casari
Publikováno v:
Blood. 120:2723-2732
von Willebrand factor (VWF) is a promising target for developing antithrombotic drugs. The absence of accessible animal models impedes the study of specific human VWF (huVWF) targeting molecules in thrombosis. huVWF is not functional in the mouse bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa985dc40d42865c28fd5c8b220548d
https://doi.org/10.1182/blood-2012-03-420042
https://doi.org/10.1182/blood-2012-03-420042
Autor:
Olivier D. Christophe, Julie Rayes, Isabelle Marx, Cécile V. Denis, Paulette Legendre, Martine J. Hollestelle, Peter J. Lenting, Philip G. de Groot
Publikováno v:
Blood. 115:4870-4877
Von Willebrand disease (VWD)–type 2B originates from a gain-of-function mutation in von Willebrand factor (VWF), resulting in enhanced platelet binding. Clinical manifestations include increased bleeding tendency, loss of large multimers, thrombocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51f739b202acdf46421b17117ce8a2f
https://doi.org/10.1182/blood-2009-11-254193
https://doi.org/10.1182/blood-2009-11-254193
Publikováno v:
ResearcherID
SummaryVon Willebrand factor (VWF) structure-function relationship has been studied only through in vitro approaches. The VWF-deficient mouse model has been extremely useful to examine the in vivo function of VWF but does not allow a more subtle anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff66e21c8561a2632a594e1c39465e1
https://doi.org/10.1055/s-0037-1616933
https://doi.org/10.1055/s-0037-1616933
Autor:
Thure Adler, Cécile V. Denis, Olivier D. Christophe, Peter J. Lenting, Isabelle Marx, Ronan Pendu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:419-424
Objective— von Willebrand Factor (vWF) structure-function relationship has been studied only in vitro. To investigate the physiological importance of particular vWF domains, we have introduced mutations into murine vWF (mvWF) cDNA inhibiting vWF bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8f3a1b070c92a24eaff80ae2f51a52
https://doi.org/10.1161/atvbaha.107.159442
https://doi.org/10.1161/atvbaha.107.159442
Autor:
Isabelle Marx, Olivier D. Christophe, Alain Rupin, Cécile V. Denis, Tony Verbeuren, Peter J. Lenting, Marie-Odile Vallez
Publikováno v:
Blood. 112(3)
The role of von Willebrand factor (VWF) in thrombosis involves its binding to a number of ligands. To investigate the relative importance of these particular interactions in the thrombosis process, we have introduced mutations into murine VWF (mVWF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7ad1fb3be7793c3539cafe3411b236
https://pubmed.ncbi.nlm.nih.gov/18487513
https://pubmed.ncbi.nlm.nih.gov/18487513
Publikováno v:
Thrombosis research. 120
Von Willebrand factor (VWF) is a multimeric plasma glycoprotein that plays a critical role in primary hemostasis, allowing the adhesion of platelets to the exposed subendothelium. The key role played by VWF in platelet adhesion suggests a potential i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7584e43a664b97ade55cc470d8a4fee5
https://pubmed.ncbi.nlm.nih.gov/18023715
https://pubmed.ncbi.nlm.nih.gov/18023715
Autor:
Cynthia M. Pruss, Peter J. Lenting, Cécile V. Denis, Isabelle Marx, Simon F. De Meyer, David Lillicrap, Philip G. de Groot, Karen Vanhoorelbeke
Publikováno v:
Blood. 109:2267-2268
Recently, Pergolizzi et al[1][1] reported in Blood about correction of the bleeding tendency in von Willebrand factor (VWF)–deficient mice via hydrodynamic delivery of murine VWF (mVWF) cDNA. The complete correction of the bleeding time was surpris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ffdf0be8e580c57fed7c337c76bf06
https://doi.org/10.1182/blood-2006-10-054718
https://doi.org/10.1182/blood-2006-10-054718