Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Isabelle Mahouche"'
Autor:
Camille Dantzer, Justine Vaché, Aude Brunel, Isabelle Mahouche, Anne-Aurélie Raymond, Jean-William Dupuy, Melina Petrel, Paulette Bioulac-Sage, David Perrais, Nathalie Dugot-Senant, Mireille Verdier, Barbara Bessette, Clotilde Billottet, Violaine Moreau
Publikováno v:
eLife, Vol 13 (2024)
Immune checkpoint inhibitors have produced encouraging results in cancer patients. However, the majority of ß-catenin-mutated tumors have been described as lacking immune infiltrates and resistant to immunotherapy. The mechanisms by which oncogenic
Externí odkaz:
https://doaj.org/article/342f26d4191d4cf39318d96525b6cc9f
Autor:
Charlotte Domblides, Isabelle Soubeyran, Lydia Lartigue, Isabelle Mahouche, Félix Lefort, Valérie Velasco, Thomas Barnetche, Patrick Blanco, Julie Déchanet-Merville, Benjamin Faustin
Publikováno v:
Cancers, Vol 12, Iss 12, p 3500 (2020)
(1) We wanted to assess the prognostic impact of inflammasomes involved in gut epithelial homeostasis and the development of human colorectal cancer (CRC). (2) We investigated the expression of inflammasome components in colonic epithelial cells at t
Externí odkaz:
https://doaj.org/article/bc65bd869f914d01bab004f664b877e6
Autor:
Simon Latour, Isabelle Mahouche, Floriane Cherrier, Lamia Azzi-Martin, Valérie Velasco, Pierre Soubeyran, Jean-Philippe Merlio, Sandrine Poglio, Laurence Bresson-Bepoldin
Publikováno v:
Cancers, Vol 10, Iss 11, p 402 (2018)
Ca2+ release-activated Ca2+ channels, composed of Orai1 and STIM1 (stromal interaction molecule 1) proteins, are the main Ca2+ entry mechanism in lymphocytes. Their role in cell migration and metastasis is demonstrated in solid cancers but it remains
Externí odkaz:
https://doaj.org/article/11baa3710d854422ab668bcbf15f0d89
Autor:
Valérie Le Morvan, Pierre Nassoy, Patricia Legoix, Céline Pangault, Simon Latour, Pierre Soubeyran, Laurence Bresson-Bepoldin, Frédéric Mourcin, Kevin Alessandri, Elise Dessauge, Martina Prochazkova-Carlotti, Julien Saint-Vanne, Lea Broca-Brisson, Nelson Hélaine, Karin Tarte, Jean-Philippe Merlio, Sylvain Baulande, Laurent Deleurme, Isabelle Mahouche, Laetitia Andrique, Céline Monvoisin, Gaëlle Recher, Christelle Dussert, Claire Lamaison, Marine Seffals
Publikováno v:
Blood Advances
Blood Advances, 2021, ⟨10.1182/bloodadvances.2020003949⟩
Blood Advances, The American Society of Hematology, 2020, ⟨10.1182/bloodadvances.2020003949⟩
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2020003949⟩
Blood Advances, 2021, ⟨10.1182/bloodadvances.2020003949⟩
Blood Advances, The American Society of Hematology, 2020, ⟨10.1182/bloodadvances.2020003949⟩
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2020003949⟩
Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as aggregates of tumor cells densely packed with their surrounding microenvironment, creating a tumor niche specific to each lymphoma subtypes. In vitro preclinical models mimicki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf8445aa993a67d7ba9a527cc53b65f
https://hal.science/hal-03367891/document
https://hal.science/hal-03367891/document
Autor:
Isabelle Mahouche, Delphine Fessart, Véronique Brouste, Eric Chevet, Isabelle Soubeyran, Pierre Soubeyran, Valérie Velasco, Simon Pernot, Serge Evrard, Jacques Robert, Frédéric Delom
BackgroundColon cancer is one of the most common leading causes of death worldwide. Prognostic at an early stage is an efficient way to decrease mortality. The Endoplasmic Reticulum (ER)-resident protein anterior gradient-2 (AGR2), a Protein Disulfid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69099a91e4c451a681a673d7bc4d083a
https://doi.org/10.1101/2021.09.07.459258
https://doi.org/10.1101/2021.09.07.459258
Autor:
Emilie Obre, Jean-François Moreau, Rodrigue Rossignol, Christelle Harly, Benoit Viollet, Angela Pappalardo, Vincent Pitard, Isabelle Soubeyran, Charlotte Domblides, Fiyaz Mohammed, Stéphane Claverol, Omar Hawchar, Sonia Netzer, Carla Cano, Layal Massara, Julie Déchanet-Merville, Carrie R. Willcox, Lydia Lartigue, Charlotte Mannat, S.P. Joyce, Benjamin Faustin, Isabelle Mahouche, Thomas Bachelet, Benjamin E. Willcox, Lionel Couzi
Publikováno v:
Science Immunology
Science Immunology, 2021, 6 (61), pp.eaba9010. ⟨10.1126/sciimmunol.aba9010⟩
Science Immunology, American Association for the Advancement of Science, 2021, 6 (61), pp.eaba9010. ⟨10.1126/sciimmunol.aba9010⟩
Science Immunology, 2021, 6 (61), pp.eaba9010. ⟨10.1126/sciimmunol.aba9010⟩
Science Immunology, American Association for the Advancement of Science, 2021, 6 (61), pp.eaba9010. ⟨10.1126/sciimmunol.aba9010⟩
International audience; Human γδ T cells contribute to tissue homeostasis and participate in epithelial stress surveillance through mechanisms that are not well understood. Here, we identified ephrin type-A receptor 2 (EphA2) as a stress antigen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984a18aa2044fcbe76e9904f01aaa897
https://www.hal.inserm.fr/inserm-03349495/file/Harly2021Eq01.pdf
https://www.hal.inserm.fr/inserm-03349495/file/Harly2021Eq01.pdf
Autor:
Gaëlle Recher, N. Helaine, Céline Monvoisin, Laurence Bresson-Bepoldin, E. Dessauge, Kevin Alessandri, Frédéric Mourcin, Isabelle Mahouche, Céline Pangault, C. Lamaison, L. Broca-Brisson, Sylvain Latour, V. Le Morvan, Marine Seffals, Pierre Nassoy, Philippe Soubeyran, C. Dussert, Karin Tarte
Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as densely packed aggregates of tumor cells and their surrounding microenvironment, creating a tumor niche specific to each lymphoma subtypes. Until now, in vitro preclinical mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c1c19ac602953a462b6e9222d95c5c
https://hal.archives-ouvertes.fr/hal-03010816/document
https://hal.archives-ouvertes.fr/hal-03010816/document
Autor:
Isabelle Mahouche, Benjamin Faustin, Isabelle Soubeyran, R Ruggieri, C Brulard, Christophe Rey, Lydia Lartigue, F. De Giorgi, François Ichas
Publikováno v:
Oncogene. 35:3190-3200
Often described as a mediator of cell cycle arrest or as a pro-apoptotic factor in stressful conditions, the MAP3K ZAK (Sterile alpha motif and leucine zipper-containing kinase) has also been proven to positively regulate epidermal growth factor rece
Autor:
Sandrine Poglio, Laurence Bresson Bepoldin, Floriane Cherrier, Isabelle Mahouche, Simon Latour, Jean-Philippe Merlio
Publikováno v:
Cancer Research. 77:1881-1881
Non-Hodgkin lymphoma is one of the most common cancer in United States representing 4% of all cancer. Diffuse large B cell lymphoma (DLBCL) is the most common and aggressive non-Hodgkin B lymphoma. One of the characteristic features of this disease i
Autor:
Christophe Rey, Isabelle Soubeyran, Lydia Lartigue, Francesca De Giorgi, François Ichas, Isabelle Mahouche, Alban Bessede, Stephane Pedeboscq
Publikováno v:
Cell cycle (Georgetown, Tex.). 12(12)
HIPK1 (homeodomain interacting protein kinase 1) is a serine/threonine kinase that belongs to the CMGC superfamily. Emerging data point to the role of HIPK1 in cancer, but it is still not clear whether it acts as a tumor suppressor or promoter. Here