Výsledky vyhledávání - "Isabelle Lena"

Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia

Autor: Isabelle Lena, Lan Bao, Zhen Ning Zhang, Zhen-Zhong Xu, Shao Qiu He, Andreas Zimmer, Tao Sun, Li-Hua Wang, Ji-Song Guan, Guo Qiang Ma, Xu Zhang, Gang Pei, Ian Kitchen, Cheng He, Hua Gao, Robert Elde

Publikováno v: Cell. 122(4)

SummaryOpioid and tachykinin systems are involved in modulation of pain transmission in the spinal cord. Regulation of surface opioid receptors on nociceptive afferents is critical for opioid analgesia. Plasma-membrane insertion of δ-opioid receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a725652e7bd2e37dc33add1358d80a
https://pubmed.ncbi.nlm.nih.gov/16122418

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Quantitative autoradiography of dopamine receptors in the brains of micro-opioid receptor knockout mice

Autor: Isabelle Lena, Ian Kitchen, Hans W. D. Matthes, Brigitte L. Kieffer

Publikováno v: Neuroscience letters. 356(3)

Given the existence of functional interactions between opioidergic and dopaminergic systems, we have analyzed by quantitative autoradiography the possible long-term adaptive changes in the expression of D(1)- and D(2)-like dopamine receptors in the b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a857b370905eef6f9f835a33bb4483
https://pubmed.ncbi.nlm.nih.gov/15036634

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5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization

Autor: Israel Alberti, Nicolas Froger, Laurence Lanfumey, Christian Jacquot, Alain M. Gardier, Nadia M.J. Rupniak, Michel Hamon, Isabelle Lena, Rosario Moratalla, Claudette Boni, Carmen De Felipe, Stephen P. Hunt

Publikováno v: ResearcherID
Scopus-Elsevier
Digital.CSIC. Repositorio Institucional del CSIC
instname

Antagonists at substance P receptors of the neurokinin 1 (NK1) type have been shown to represent a novel class of antidepressant drugs, with comparable clinical efficacy to the selective serotonin (5-HT) reuptake inhibitors (SSRIs). Because 5-HT1A re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44837826f1abf42e3b7107927a55ace
https://pubmed.ncbi.nlm.nih.gov/11588191

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Autoradiographic mapping of the opioid receptor-like 1 (ORL1) receptor in the brains of the mu-, delta-, kappa- opioid receptor knockout mice

Autor: Robin James Goody, S Clarke, Roberta Lattanzi, Frédéric Simonin, Ian Kitchen, Dominique Filliol, Susan Slowe, Lucia Negri, Brigitte L. Kieffer, Isabelle Lena, Hans W. D. Matthes

The opioid receptor-like 1 (ORL1) receptor shares a high degree of sequence homology with the classical mu-, delta- and kappa-opioid receptors and a functional mutual opposition between these receptors has been suggested. To further address this poss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc5d19c48fcd4a1442222e5dbf8830a
http://hdl.handle.net/11573/131600

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Akademický článek

The Intracellular Na+/H+ Exchanger NHE7 Effects a Na+-Coupled, but Not K+-Coupled Proton-Loading Mechanism in Endocytosis

Autor: Nina Milosavljevic, Michaël Monet, Isabelle Léna, Frédéric Brau, Sandra Lacas-Gervais, Sylvain Feliciangeli, Laurent Counillon, Mallorie Poët

Publikováno v: Cell Reports, Vol 7, Iss 3, Pp 689-696 (2014)

Vesicular H+-ATPases and ClC-chloride transporters are described to acidify intracellular compartments, which also express the highly conserved Na+/H+ exchangers NHE6, NHE7, and NHE9. Mutations of these exchangers cause autism-spectrum disorders and

Externí odkaz: https://doaj.org/article/5ed5e3d9e4a14ff6887a40dbb4eb51a3

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