Výsledky vyhledávání - "Isabelle Leisten"

Osteogenesis of Heterotopically Transplanted Mesenchymal Stromal Cells in Rat Models of Chronic Kidney Disease

Autor: Isabelle Leisten, Rafael Kramann, Barbara M. Klinkhammer, Rebekka K. Schneider, Ruth Knüchel, Jürgen Floege, Uta Kunter, Vincent Brandenburg, Josef Ehling

Publikováno v: Journal of Bone and Mineral Research. 28:2523-2534

The current study is based on the hypothesis of mesenchymal stromal cells (MSCs) contributing to soft-tissue calcification and ectopic osteogenesis in chronic kidney disease (CKD). Rat MSCs were transplanted intraperitoneally in an established three-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f469ab2027fe9450e471d8c8c8f84b5
https://doi.org/10.1002/jbmr.1994

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3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche

Autor: Isabelle Leisten, Manfred Bovi, Mónica S. Ventura Ferreira, Sabine Neuss, Patrick Ziegler, Wolfgang Wagner, Ruth Knüchel, Rafael Kramann, Rebekka K. Schneider

Publikováno v: Biomaterials. 33:1736-1747

Here, we propose a collagen-based three-dimensional (3D) environment for hematopoietic stem and progenitor cells (HPC) with mesenchymal stem cells (MSC) derived either from bone marrow (BM) or umbilical cord (UC), to recapitulate the main components

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0483bb9937ccbd91625b70687af4d2
https://doi.org/10.1016/j.biomaterials.2011.11.034

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Osteogenesis of heterotopically transplanted mesenchymal stromal cells in rat models of chronic kidney disease

Autor: Rafael, Kramann, Uta, Kunter, Vincent M, Brandenburg, Isabelle, Leisten, Josef, Ehling, Barbara M, Klinkhammer, Ruth, Knüchel, Jürgen, Floege, Rebekka K, Schneider

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 28(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43e9db04ea5d83eb9e4ac3941b683928
https://pubmed.ncbi.nlm.nih.gov/23703894

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Novel insights into osteogenesis and matrix remodelling associated with calcific uraemic arteriolopathy

Autor: Rafael Kramann, Leon J. Schurgers, Vincent Brandenburg, Isabelle Leisten, Markus Ketteler, Manfred Bovi, Ruth Knüchel, Rebekka K. Schneider, Willi Jahnen-Dechent, Saskia Westphal, Jürgen Floege

Publikováno v: Nephrology Dialysis Transplantation, 28(4), 856-868. Oxford University Press

Background Calcific uraemic arteriolopathy (CUA) or calciphylaxis is a rare, life-threatening disease predominantly occurring in patients with end-stage renal disease. Its pathogenesis has been suggested to include ectopic osteogenesis in soft tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc24633f204fe0a1ee4b920c54182b20
https://pubmed.ncbi.nlm.nih.gov/23223222

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Use of multilocus methylation-specific single nucleotide primer extension (MS-SNuPE) technology in diagnostic testing for human imprinted loci

Autor: Thomas Eggermann, Lukas Soellner, Matthias Begemann, Isabelle Leisten, Sabrina Spengler, Klaus Zerres

Publikováno v: Epigenetics. 7(5)

A number of diseases have been found to be linked to aberrant methylation of specific genes. However, most of the routine diagnostic techniques to detect epigenetic disturbances are restricted to single loci. Additionally, a precise quantification of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e019d54635c6d77a4149d018de3e76
https://pubmed.ncbi.nlm.nih.gov/22419125

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Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues

Autor: Michael Baudis, H Segerer, Isabelle Leisten, Thomas Eggermann, Reiner Siebert, Andrea Haake, S Markus, Thomas Rupprecht, Matthias Begemann, Susanne Fricke-Otto, Deniz Kanber, Karin Buiting, Gerhard Binder, Sabrina Spengler, R Mühlenberg

In all known congenital imprinting disorders an association with aberrant methylation or mutations at specific loci was well established. However, several patients with transient neonatal diabetes mellitus (TNDM), Silver-Russell syndrome (SRS) and Be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b86b35c716447e8c25b839532bd2c1
https://www.zora.uzh.ch/id/eprint/35623/

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Molecular Analyses of the BORIS Gene in Children with Silver-Russell Syndrome

Autor: Thomas Eggermann, Nadine Schönherr, Sabrina Spengler, Gesa Schwanitz, Magdalena Gogiel, Isabelle Leisten, Gerhard Binder, Alina T. Midro

Publikováno v: ResearcherID

KEYWORDS Silver-Russell Syndrome. Hypomethylation. Imprinting. ICR.BORIS ABSTRACT Silver-Russell syndrome (SRS) is a heterogeneous disorder associated with intrauterine and postnatal growth retardation, skeletal asymmetry and facial dysmorphisms. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709c13752579466d83013d4739444bbd
https://doi.org/10.31901/24566330.2009/09.03-04.09

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