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of 22
pro vyhledávání: '"Isabelle Lee"'
Autor:
Mohammed M. Abusayf, Yu-Chi Liu, Evelina Han, Isabelle Lee Xin Yu, Andri K. Riau, Jodhbir S. Mehta
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 639 (2024)
The aim of our study is to investigate the feasibility and outcomes of using a femtosecond laser (FSL) platform (Ziemer LDV Z8) for deep anterior lamellar keratoplasty (DALK), enabling the creation of mushroom-shaped graft–host junctions, lamellar
Externí odkaz:
https://doaj.org/article/66f06a24062548309102ead8dc942093
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Anxiety and depression are common, disabling and frequently start in youth, underscoring the need for effective, accessible early interventions. Empirical data and consultations with lived experience youth representatives suggest
Externí odkaz:
https://doaj.org/article/f2c34eb520f745cfa702f64f5ab06430
Akademický článek
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Autor:
Molly Tzu Yu Lin, Isabelle Lee, Wei-Li Chen, Mei-Yun Chen, Jodhbir Mehta, Gary Yam, Gary Peh, Yu-Chi Liu
Publikováno v:
Tissue Engineering Part C: Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d02843df4b03699a3bf7bc6aa06563
https://doi.org/10.1089/ten.tec.2023.0054
https://doi.org/10.1089/ten.tec.2023.0054
Publikováno v:
Dermatitis : contact, atopic, occupational, drug. 33(2)
Reliable human potency data are necessary for conducting quantitative risk assessments, as well as development and validation of new nonanimal methods for skin sensitization assessments. Previously, human skin sensitization potency of fragrance mater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3973df407507bb4880ef287ab31aef
https://pubmed.ncbi.nlm.nih.gov/35170517
https://pubmed.ncbi.nlm.nih.gov/35170517
Publikováno v:
BMC Psychiatry
BMC Psychiatry, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Psychiatry, Vol 21, Iss 1, Pp 1-17 (2021)
BackgroundAnxiety and depression are common, disabling and frequently start in youth, underscoring the need for effective, accessible early interventions. Empirical data and consultations with lived experience youth representatives suggest that malad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff99fc2fb6a0d3287c2cb3249bdd9a0f
http://europepmc.org/articles/PMC8386061
http://europepmc.org/articles/PMC8386061
Autor:
Isabelle Lee, Mihwa Na, Devin O'Brien, Rahul Parakhia, Nathalie Alépée, Walter Westerink, Irene Eurlings, Anne Marie Api
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 79
The U-SENS™ assay was developed to address the third key event of the skin sensitization adverse outcome pathway (AOP) and is described in OECD test guideline 442E, Annex II. A dataset of 68 fragrance ingredients comprised of 7 non-sensitizers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979f1ffe126875ecf854ab06ca4658e7
https://pubmed.ncbi.nlm.nih.gov/34902536
https://pubmed.ncbi.nlm.nih.gov/34902536
Autor:
Mihwa Na, Devin O'Brien, G. Frank Gerberick, Petra S. Kern, Maura Lavelle, Isabelle Lee, Rahul Parakhia, Cindy Ryan, Anne Marie Api
Publikováno v:
Regulatory Toxicology and Pharmacology. 130:105128
Potency determination of potential skin sensitizers in humans is essential for quantitative risk assessment and proper risk management. SENS-IS is an in vitro test based on a reconstructed human skin model, that was developed to predict the hazard an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a2102ee5b10027ca0897586200a027
https://doi.org/10.1016/j.yrtph.2022.105128
https://doi.org/10.1016/j.yrtph.2022.105128
Publikováno v:
Food and Chemical Toxicology. 159:112705
Some fragrance ingredients may have the potential to induce skin sensitization in humans but can still be safely formulated into consumer products. Quantitative Risk Assessment (QRA) for dermal sensitization is required to determine safe levels at wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8dbf2f806dcc378cc9bdf235f004779
https://doi.org/10.1016/j.fct.2021.112705
https://doi.org/10.1016/j.fct.2021.112705
Autor:
Susan Kaufman, Zhang Yanchen, Joshua Haznedar, Daniel Menezes, Matthew Burger, Xiaohua Xin, Aaron Smith, Frazier Kelly, Sauveur-Michel Maira, Allan S. Wagman, Zhi-Jie Ni, Keith B. Pfister, Kay Huh, Isabel Zaror, Thomas Hendrickson, Joelle Verhagen, Gordana Atallah, Kevin Shoemaker, Bartulis Sarah, Michael Chin, Simon Ng, Kenneth Crawford, Dirksen E. Bussiere, Ed Iwanowicz, Mark Knapp, Isabelle Lee, Hanne Merritt, Marion Wiesmann, Charles Voliva, Sabina Pecchi
Publikováno v:
ACS Medicinal Chemistry Letters. 2:774-779
Phosphoinositide-3-kinases (PI3Ks) are important oncology targets due to the deregulation of this signaling pathway in a wide variety of human cancers. Herein we describe the structure guided optimization of a series of 2-morpholino, 4-substituted, 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31ec0f7f889d4d0d8c5baf0ae8c19fd
https://doi.org/10.1021/ml200156t
https://doi.org/10.1021/ml200156t