Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Isabelle Le Roux"'
Autor:
Rana Salam, Alexa Saliou, Franck Bielle, Mathilde Bertrand, Christophe Antoniewski, Catherine Carpentier, Agusti Alentorn, Laurent Capelle, Marc Sanson, Emmanuelle Huillard, Léa Bellenger, Justine Guégan, Isabelle Le Roux
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Senescence can have beneficial and detrimental impact on cancer progression depending on the cellular context. Here the authors show that NRF2 regulates the senescence phenotype in malignant cells which consequently contribute to glioblastoma progres
Externí odkaz:
https://doaj.org/article/921a4435b8f04a829da3f93afb4e6978
Autor:
Shai Rosenberg, Iva Simeonova, Franck Bielle, Maite Verreault, Bertille Bance, Isabelle Le Roux, Mailys Daniau, Arun Nadaradjane, Vincent Gleize, Sophie Paris, Yannick Marie, Marine Giry, Marc Polivka, Dominique Figarella-Branger, Marie-Hélène Aubriot-Lorton, Chiara Villa, Alexandre Vasiljevic, Emmanuèle Lechapt-Zalcman, Michel Kalamarides, Ariane Sharif, Karima Mokhtari, Stefano Maria Pagnotta, Antonio Iavarone, Anna Lasorella, Emmanuelle Huillard, Marc Sanson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Chordoid glioma is a slow growing diencephalic tumor whose mutational landscape is poorly characterized. Here, the authors perform whole-exome and RNA-sequencing and find that 15 of 16 chordoid glioma cases studied harbor the same PRKCA mutation whic
Externí odkaz:
https://doaj.org/article/47f7d121d4304c4ca98cb2dbb0a6edde
Autor:
Rana Salam, Alexa Saliou, Franck Bielle, Mathilde Bertrand, Christophe Antoniewski, Catherine Carpentier, Agusti Alentorn, Laurent Capelle, Marc Sanson, Emmanuelle Huillard, Léa Bellenger, Justine Guégan, Isabelle Le Roux
Publikováno v:
Nature Communications
Nature Communications, 2023, 14 (1), pp.441. ⟨10.1038/s41467-023-36124-9⟩
Nature Communications, 2023, 14 (1), pp.441. ⟨10.1038/s41467-023-36124-9⟩
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, yet it remains refractory to systemic therapy. Elimination of senescent cells has emerged as a promising new treatment approach against cancer. Here, we investigated the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4363c667e35c6072be03c62728e7e6ee
https://hal.science/hal-03864324
https://hal.science/hal-03864324
Autor:
Ana Cumano, Shahragim Tajbakhsh, Pierre Rocheteau, Barbara Gayraud-Morel, Aurélie Jory, Isabelle Le Roux, Michel Cohen-Tannoudji
Publikováno v:
STEM CELLS
Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), 2009, 27 (11), pp.2769-80. ⟨10.1002/stem.220⟩
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 2009, 27 (11), pp.2769-80. ⟨10.1002/stem.220⟩
STEM CELLS; Vol 27
Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), 2009, 27 (11), pp.2769-80. ⟨10.1002/stem.220⟩
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 2009, 27 (11), pp.2769-80. ⟨10.1002/stem.220⟩
STEM CELLS; Vol 27
Multiple cell types arise from cells in the dermomyotome of the somite that express Pax3 and Pax7, and myogenesis is regulated by Notch signaling. The asymmetric cell fate determinant Numb is thought to promote differentiation of skeletal muscle and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff14851662fc50de6df9c47fb8043b3
Autor:
François Guillemot, Isabelle Le Roux, Vanessa Ribes, Pascal Dollé, Laurent Bianchetti, Fanny Stutzmann
Publikováno v:
Developmental Biology
Developmental Biology, Elsevier, 2008, 321 (2), pp.470-81. ⟨10.1016/j.ydbio.2008.06.003⟩
Developmental Biology, 2008, 321 (2), pp.470-81. ⟨10.1016/j.ydbio.2008.06.003⟩
Developmental Biology, Elsevier, 2008, 321 (2), pp.470-81. ⟨10.1016/j.ydbio.2008.06.003⟩
Developmental Biology, 2008, 321 (2), pp.470-81. ⟨10.1016/j.ydbio.2008.06.003⟩
International audience; A central issue during embryonic development is to define how different signals cooperate in generating unique cell types. To address this issue, we focused on the function and the regulation of the proneural gene Neurogenin2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0d82ad6afa73f253dc0a2e03dfedec
https://doi.org/10.1016/j.ydbio.2008.06.003
https://doi.org/10.1016/j.ydbio.2008.06.003
Autor:
Patrick Blader, Nadine Fischer, Sepand Rastegar, Stephanie Albert, Isabelle Le Roux, Uwe Strähle, Ferenc Müller
Publikováno v:
Developmental Biology. 252(1):1-14
The floor plate is an organising centre that controls neural differentiation and axonogenesis in the neural tube. The axon guidance molecule Netrin1 is expressed in the floor plate of zebrafish embryos. To elucidate the regulatory mechanisms underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43acdfc265094ed3b75c599dd13f4b8
Autor:
Laura K. Cole, Isabelle Le Roux, Doris K. Wu, Julian Lewis, Fábio Daumas Nunes, Edward M. Laufer
Publikováno v:
The Journal of Comparative Neurology. 424:509-520
The chicken inner ear is a remarkably complex structure consisting of eight morphologically distinct sensory organs. Unraveling how these sensory organs are specified during development is key to understanding how such a complex structure is generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a2c9fbc468440ddd9b7cf8e14656af
https://doi.org/10.1002/1096-9861(20000828)424:3<509::aid-cne8>3.0.co
https://doi.org/10.1002/1096-9861(20000828)424:3<509::aid-cne8>3.0.co
Autor:
Barbara Varnum-Finney, Spyros Artavanis-Tsakonas, Isabelle Le Roux, Grace E. Gray, David A. Flowers, Louise E. Purton, Monica Yu, Kateri A. Moore, Irwin D. Bernstein, Steven J. Staats, Carolyn Brashem-Stein, Robert S. Mann
Publikováno v:
Scopus-Elsevier
We examined the expression of two members of theNotch family, Notch-1 and Notch-2, and one Notch ligand, Jagged-1, in hematopoietic cells. Both Notch-1 and Notch-2 were detected in murine marrow precursors (Lin−Sca-1+c-kit+). The Notch ligand, Jagg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d9a4d31617977fbb6128d789c711d0
https://doi.org/10.1182/blood.v91.11.4084
https://doi.org/10.1182/blood.v91.11.4084
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2009, 136 (4), pp.665-76. ⟨10.1242/dev.016204⟩
Development (Cambridge, England), 2009, 136 (4), pp.665-76. ⟨10.1242/dev.016204⟩
Development (Cambridge, England), Company of Biologists, 2009, 136 (4), pp.665-76. ⟨10.1242/dev.016204⟩
Development (Cambridge, England), 2009, 136 (4), pp.665-76. ⟨10.1242/dev.016204⟩
International audience; The progressive generation of embryonic trunk structures relies on the proper patterning of the caudal epiblast, which involves the integration of several signalling pathways. We have investigated the function of retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f1d0f2d92c9a7d8c1116bb3639a834
https://www.hal.inserm.fr/inserm-00357464
https://www.hal.inserm.fr/inserm-00357464
Autor:
Pascal Doll, Jabier Gallego Llamas, Vanessa Ribes, Julien Vermot, Isabelle Le Roux, Karen Niederreither
Publikováno v:
Genetically Engineered Mice Handbook ISBN: 9780849322204
Genetically Engineered Mice Handbook
Genetically Engineered Mice Handbook
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d28fbe561487d433f67bb7786236b19
https://doi.org/10.1201/9781420039078.ch21
https://doi.org/10.1201/9781420039078.ch21