Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Isabelle Jutras"'
Autor:
Michel Desjardins, Isabelle Jutras
Publikováno v:
Annual Review of Cell and Developmental Biology. 21:511-527
Phagocytosis, the process by which cells engulf large particles, requires a substantial contribution of membranes. Recent studies have revealed that intracellular compartments, including endocytic organelles and the endoplasmic reticulum (ER), can en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3da14208298b84d8267fc75fb7c3245
https://doi.org/10.1146/annurev.cellbio.20.010403.102755
https://doi.org/10.1146/annurev.cellbio.20.010403.102755
Publikováno v:
Journal of Biological Chemistry. 275:40337-40343
The proprotein convertase PC1 is a protease whose activity is largely confined to the dense core secretory granules of neuroendocrine cells. Efficient processing of PC1 substrates in granules requires a mechanism that will both limit the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13207139c6b9c49cbfade0de3d64105a
https://doi.org/10.1074/jbc.m004757200
https://doi.org/10.1074/jbc.m004757200
Publikováno v:
Journal of Biological Chemistry. 272:15184-15188
PC1, a neuroendocrine member of the prohormone convertase family of serine proteinases, is implicated in the processing of proproteins in the secretory pathway. PC1 is synthesized as a zymogen and cleaves not only its own profragment in the endoplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596f438dda9127731c4c6b4c4706f24d
https://doi.org/10.1074/jbc.272.24.15184
https://doi.org/10.1074/jbc.272.24.15184
Autor:
Nabil G. Seidah, Christian F. Deschepper, Robert Day, Véronique Brechler, Kenneth W. Gross, Isabelle Jutras, Mireille Laframboise, Timothy L. Reudelhuber
Publikováno v:
Kidney International. 51:104-109
Prorenin activation and prohormone convertases in the mouse As4.1 cell line. The precise identification of prorenin-processing enzymes has been hampered by the very low abundance of juxtaglomerular cells in the kidney. Recently, an immortalized renin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28dc8541435a1786c892553d46e5c0d
https://doi.org/10.1038/ki.1997.13
https://doi.org/10.1038/ki.1997.13
Publikováno v:
ResearcherID
We isolated a cDNA clone encoding the human prohormone convertase PC5 from human adrenal gland mRNA. The deduced protein sequence would encode a 915 amino acid preproPC5 that shares a very high degree of homology with previously cloned rat and mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017a4a2d62647b1ac81e5116f8106291
https://doi.org/10.1161/01.hyp.28.5.840
https://doi.org/10.1161/01.hyp.28.5.840
Autor:
Jean-François Dermine, Sylvie Laboissiere, Isabelle Jutras, Pierre Thibault, Sophie Duclos, Jonathan Boulais, Stephen W. Michnick, Christian R. Landry, Luis B. Barreiro, Gilles A. Lajoie, Michel Desjardins, Guillaume Goyette, Nicholas J. Carruthers
After their formation at the cell surface, phagosomes become fully functional through a complex maturation process involving sequential interactions with various intracellular organelles. In the last decade, series of data indicated that some of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813903d6c1f8f009636eaa4a9b727086
https://europepmc.org/articles/PMC3494184/
https://europepmc.org/articles/PMC3494184/
Autor:
Pierre Thibault, Eustache Paramithiotis, Isabelle Jutras, Mathieu Houde, Paul Kearney, Sylvie Laboissiere, Michel Desjardins, Nathan L. Currier, Eric Bonneil, Patrice Hugo, Sophie Duclos, Jonathan Boulais
Publikováno v:
Molecularcellular proteomics : MCP. 7(4)
Macrophages are immune cells that function in the clearance of infectious particles. This process involves the engulfment of microbes into phagosomes where these particles are lysed and degraded. In the current study, we used a large scale quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5cefa4ea2a593ef996063521c8193d
https://pubmed.ncbi.nlm.nih.gov/18156134
https://pubmed.ncbi.nlm.nih.gov/18156134
Autor:
Gopal Thinakaran, Isabelle Jutras, Annie Laplante, Michel Desjardins, Sylvain Brunet, Jonathan Boulais
Publikováno v:
The Journal of biological chemistry. 280(43)
Gamma-secretase is a high molecular mass protein complex that catalyzes the intramembrane cleavage of its protein substrates. Two proteins involved in phagocytosis, CD44 and the low density lipoprotein receptor-related protein, are gamma-secretase su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02e065fd963a8cb95214b709fb518b7
https://pubmed.ncbi.nlm.nih.gov/16103123
https://pubmed.ncbi.nlm.nih.gov/16103123
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2003, 71 (1), pp.260-6. ⟨10.1128/IAI.71.1.260-266.2003⟩
Infection and Immunity, 2003, 71 (1), pp.260-6. ⟨10.1128/IAI.71.1.260-266.2003⟩
Infection and Immunity, American Society for Microbiology, 2003, 71 (1), pp.260-6. ⟨10.1128/IAI.71.1.260-266.2003⟩
Infection and Immunity, 2003, 71 (1), pp.260-6. ⟨10.1128/IAI.71.1.260-266.2003⟩
Chlamydiae are bacterial pathogens which develop strictly inside the epithelial cells of their hosts. The mechanism used by chlamydiae to enter cells is not well characterized; however, it is thought to consist of a receptor-mediated process. In addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f463ce4d8696dc7c339861685ce9de
https://hal-pasteur.archives-ouvertes.fr/pasteur-00166957
https://hal-pasteur.archives-ouvertes.fr/pasteur-00166957
Autor:
Timothy L. Reudelhuber, Chantal Mercure, Véronique Brechler, Danielle Methot, Isabelle Jutras
Publikováno v:
Aspartic Proteinases ISBN: 9781461374527
Largely because of its importance in the pathophysiology of cardiovascular diseases, renin has been intensely studied as a target for drug inhibition. Like most other aspartyl proteases, mammalian renins are synthesized in vivo as inactive precursors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1bd45d705daaa0eba1cf7aa2e5d97c4
https://doi.org/10.1007/978-1-4615-5373-1_32
https://doi.org/10.1007/978-1-4615-5373-1_32