Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Isabelle Hostein"'
Autor:
Yu Fu, Marie Karanian, Raul Perret, Axel Camara, François Le Loarer, Myriam Jean-Denis, Isabelle Hostein, Audrey Michot, Françoise Ducimetiere, Antoine Giraud, Jean-Baptiste Courreges, Kevin Courtet, Yech’an Laizet, Etienne Bendjebbar, Jean Ogier Du Terrail, Benoit Schmauch, Charles Maussion, Jean-Yves Blay, Antoine Italiano, Jean-Michel Coindre
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Risk assessment of gastrointestinal stromal tumor (GIST) according to the AFIP/Miettinen classification and mutational profiling are major tools for patient management. However, the AFIP/Miettinen classification depends heavily on mitotic co
Externí odkaz:
https://doaj.org/article/75a03086c3eb458f956500ff25fbf5f3
Autor:
Sophie Cousin, Thomas Grellety, Maud Toulmonde, Céline Auzanneau, Emmanuel Khalifa, Yec’han Laizet, Kevin Tran, Sylvestre Le Moulec, Anne Floquet, Delphine Garbay, Jacques Robert, Isabelle Hostein, Isabelle Soubeyran, Antoine Italiano
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-3 (2017)
Abstract Previous precision medicine studies have investigated conventional molecular techniques and/or limited sets of gene alterations. The aim of this study was to describe the impact of the next-generation sequencing of the largest panel of genes
Externí odkaz:
https://doaj.org/article/30b626a184794d59ac5cd63e77f5fa69
Autor:
Audrey Laroche, Kevin Tran-Cong, Vanessa Chaire, Pauline Lagarde, Isabelle Hostein, Jean-Michel Coindre, Frederic Chibon, Agnes Neuville, Tom Lesluyes, Carlo Lucchesi, Antoine Italiano
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0137794 (2015)
Nutlin inhibits TP53-MDM2 interaction and is under investigation in soft-tissue sarcomas (STS) and other malignancies. Molecular mechanisms of secondary resistance to nutlin in STS are unknown. We performed whole-transcriptome sequencing (RNA-seq) on
Externí odkaz:
https://doaj.org/article/a598f0172ac0428580201b2b16c1f32b
Autor:
Gaëlle Pérot, Isabelle Soubeyran, Agnès Ribeiro, Benjamin Bonhomme, Frédérique Savagner, Nathalie Boutet-Bouzamondo, Isabelle Hostein, Françoise Bonichon, Yann Godbert, Frédéric Chibon
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87170 (2014)
Thyroid carcinoma is the most common endocrine malignant tumor and accounts for 1% of all new malignant diseases. Among all types and subtypes of thyroid cancers that have been described so far, papillary thyroid carcinoma is the most frequent. The s
Externí odkaz:
https://doaj.org/article/de8f375e82aa4fc4b4bebfa102f2de5b
Autor:
Raul Perret, Zaki Malaka, Valérie Velasco, Francisco Llamas-Gutierrez, Mickael Ropars, Pierre-Antoine Linck, Isabelle Hostein, Rihab Azmani, Isabelle Valo, Louise Galmiche, Anne Moreau, Gonzague de Pinieux, Audrey Michot, Dorian Bochaton, Jean-Michel Coindre, François Le Loarer
Publikováno v:
American Journal of Surgical Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a0e746fa3f47d8f0ff745e6e9c2b6f0
https://doi.org/10.1097/pas.0000000000002051
https://doi.org/10.1097/pas.0000000000002051
Publikováno v:
Annales de Pathologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2908daba56fbe10de973af05d1ec3278
https://doi.org/10.1016/j.annpat.2023.04.005
https://doi.org/10.1016/j.annpat.2023.04.005
Autor:
Frédéric Chibon, Maria Debiec-Rychter, Jean-Michel Coindre, Alain Aurias, Patrick Schöffski, Raf Sciot, Agnieszka Wozniak, Agnès Neuville, Isabelle Hostein, Valérie Dapremont, Céline Brulard, Audrey Kauffmann, Gaëlle Pérot, Pauline Lagarde
Purpose: The importance of KIT and PDGFRA mutations in the oncogenesis of gastrointestinal stromal tumors (GIST) is well established, but the genetic basis of GIST metastasis is poorly understood. We recently published a 67 gene expression prognostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503de78825e583bcabf8add8ab6770cf
https://doi.org/10.1158/1078-0432.c.6519807.v1
https://doi.org/10.1158/1078-0432.c.6519807.v1
Autor:
Maria Debiec-Rychter, Jean-Michel Coindre, Raf Sciot, Eva Wardelmann, Janusz A. Siedlecki, Jean-Yves Blay, Janusz Limon, Elzbieta Bylina, Axel Le Cesne, Hans-Ulrich Schildhaus, Isabelle Hostein, Isabelle Ray-Coquard, Patrick Schöffski, Piotr Rutkowski, Agnieszka Wozniak
Purpose: Although the mutational status in gastrointestinal stromal tumors (GIST) can predict the response to treatment with tyrosine kinase inhibitors, the role of tumor genotype as a prognostic factor remains controversial. The ConticaGIST study so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4054297be0e642582e6e2260c1ed691
https://doi.org/10.1158/1078-0432.c.6522900.v1
https://doi.org/10.1158/1078-0432.c.6522900.v1
Autor:
Maria Debiec-Rychter, Jean-Michel Coindre, Raf Sciot, Eva Wardelmann, Janusz A. Siedlecki, Jean-Yves Blay, Janusz Limon, Elzbieta Bylina, Axel Le Cesne, Hans-Ulrich Schildhaus, Isabelle Hostein, Isabelle Ray-Coquard, Patrick Schöffski, Piotr Rutkowski, Agnieszka Wozniak
Legend for supplementary Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1b4d8eb658d4e944721eb63dc8dd65
https://doi.org/10.1158/1078-0432.22454997.v1
https://doi.org/10.1158/1078-0432.22454997.v1
Autor:
Maria Debiec-Rychter, Jean-Michel Coindre, Raf Sciot, Eva Wardelmann, Janusz A. Siedlecki, Jean-Yves Blay, Janusz Limon, Elzbieta Bylina, Axel Le Cesne, Hans-Ulrich Schildhaus, Isabelle Hostein, Isabelle Ray-Coquard, Patrick Schöffski, Piotr Rutkowski, Agnieszka Wozniak
Figure S1. Disease free survival grouped according to the presence of KIT ex. 11 mutations: KITdel-inc557/558 vs. other deletions vs. duplications vs. substitutions overall (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f2049146ff8f3ed90521bad3695c31
https://doi.org/10.1158/1078-0432.22455000.v1
https://doi.org/10.1158/1078-0432.22455000.v1