Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Isabelle Heulard"'
Publikováno v:
Epilepsia. 63(5)
Stiripentol (STP; Diacomit®) is an antiepileptic drug indicated for Dravet syndrome that has been identified as a γ-aminobutyric acid (GABAergic) positive allosteric modulator. Dravet syndrome is characterized by multiple seizure types: generalized
Publikováno v:
Alcohol. 43:197-206
Change in the function of gamma-aminobutyric acid(A) (GABA(A)) receptors attributable to alterations in receptor subunit composition is one of main molecular mechanisms with those affecting the glutamatergic system which accompany prolonged alcohol (
Publikováno v:
Psychopharmacology. 197:523-534
A disordered regulation of neuroactive steroids release in response to acute stress could induce GABAergic dysfunctions underlying anxiety disorders.First, we conducted studies indicating that a short immobilization stress in anxious Balb/cByJ mice p
Nefopam blocks voltage-sensitive sodium channels and modulates glutamatergic transmission in rodents
Publikováno v:
Brain Research. 1013:249-255
In order to specify the nature of interactions between the analgesic compound nefopam and the glutamatergic system, we examined the effects of nefopam on binding of specific ligands on the three main subtypes ionotropic glutamate receptors: N-methyl-
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 21(6)
Dysfunction of GABAergic transmission related to abnormal expression of GABA(A) receptor subunits in specific brain regions underlies some pathological anxiety states. Besides involvement of the benzodiazepine recognition site of GABA(A) receptor in
Publikováno v:
Neuroscience letters. 353(2)
We hypothesized that functional changes in the GABAergic system induced by stress would differ between two inbred mouse strains BALB/cByJ and C57BL/6J. We compared the effects of restraint stress and of the anxiolytic drug etifoxine (EFX) on the dura