Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Isabelle Guillemot"'
Publikováno v:
Experimental Cell Research. 310:319-330
All-trans-retinoic acid (RA) and 1alpha,25-dihydroxyvitamin D3 (1,25D3) are involved in the control of hematopoiesis and have been suggested to play a role in cellular differentiation and are as such potent inducers of differentiation of myeloid leuk
Autor:
Christine Chomienne, Isabelle Guillemot, Fabien Zassadowski, Sylvie Chevret, Pierre Fenaux, Bruno Cassinat, Lionel Ades, Marie-Hélène Schlageter
Publikováno v:
British Journal of Haematology. 142:998-1000
Autor:
Hervé Dombret, Djaouida Bengoufa, Marika Pla, Marie Robin, Marie-Hélène Schlageter, Philippe Rousselot, Pierre Fenaux, Juliette Andreu-Gallien, Jérôme Larghero, Isabelle Guillemot, Christine Chomienne, Emmanuel Raffoux, Carine Robert, Dominique Charron, Rose Ann Padua, Katerina Pokorna
Publikováno v:
Blood. 108:1972-1974
In an acute promyelocytic leukemia (APL)-transplantable mouse model, we previously reported the presence of antibodies recognizing PML-RARalpha and RARalpha in the sera of ATRA-treated mice. To evaluate this immune response, we determined the prevale
Autor:
Nicole Balitrand, Sylvie Chevret, Isabelle Guillemot, M L Menot, Fabien Zassadowski, Christine Chomienne, Bruno Cassinat, Laurent Degos, Pierre Fenaux
Publikováno v:
Blood. 98:2862-2864
Acute promyelocytic leukemia (APL) blasts possess a unique sensitivity to the differentiating effects of all-transretinoic acid (ATRA). Multicenter trials confirm that the combination of differentiation and cytotoxic therapy prolongs survival in APL
Autor:
Martine Escoffre-Barbe, Bruno Cassinat, Emmanuel Raffoux, Marie-Hélène Schlageter, A Parry, Jean-Luc Harousseau, Fabien Zassadowski, Philippe Rousselot, Sylvie Chevret, André Baruchel, Chantal Himberlin, Pierre Fenaux, Christine Chomienne, Jean-Yves Cahn, Hervé Dombret, Oumedaly Reman, Denis Guyotat, Didier Bouscary, Olivier Legrand, Isabelle Guillemot, Stéphane de Botton, Martine Gardembas, Charikleia Kelaidi, Lionel Ades
Publikováno v:
Leukemia research. 33(9)
10–20% of APL patients relapse and the challenge remains to early identify these patients to improve survival rate. We report PML-RARα transcript detection by RQ-PCR in 260 consecutive APL patients ( n = 970 samples). 223 patients with samples of
Autor:
Bruno, Cassinat, Isabelle, Guillemot, Cécile, Moluçon-Chabrot, Fabien, Zassadowski, Pierre, Fenaux, Olivier, Tournilhac, Christine, Chomienne
Publikováno v:
Haematologica. 91
Rare cases of acute promyelocytic leukemia (APL) are associated with a t(11;17) translocation and a PLZF-RARalpha fusion transcript. Because of molecular specificities of the fusion protein, ATRA efficiency is often reduced in these cases. We present
Autor:
Jean-Noël Bastie, Christine Chomienne, Fabien Guidez, Jérôme Larghero, Cynthia Calabresse, Laurent Delva, Isabelle Guillemot, Nicole Balitrand
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 18(11)
Granulocytes and monocytes originate from a common committed progenitor cell. Commitment to either granulocytic or monocytic lineage is triggered by specific extracellular signals involving cytokines or nuclear receptor ligands (all-trans-retinoic ac