Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Isabelle Guenon"'
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Akademický článek
Maternal Nutrition during Pregnancy Affects Testicular and Bone Development, Glucose Metabolism and Response to Overnutrition in Weaned Horses Up to Two Years.
Autor: Morgane Robles, Camille Gautier, Luis Mendoza, Pauline Peugnet, Cédric Dubois, Michèle Dahirel, Jean-Philippe Lejeune, Isabelle Caudron, Isabelle Guenon, Sylvaine Camous, Anne Tarrade, Laurence Wimel, Didier Serteyn, Hélène Bouraima-Lelong, Pascale Chavatte-Palmer
Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0169295 (2017)
Pregnant mares and post-weaning foals are often fed concentrates rich in soluble carbohydrates, together with forage. Recent studies suggest that the use of concentrates is linked to alterations of metabolism and the development of osteochondrosis in
Externí odkaz: https://doaj.org/article/6adb1a3e5dfa4b6d8273f2fb0b88b808
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2
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke
Autor: C. Le Quement, Vincent Lagente, V. Cayron-Elizondo, Samuel Santos Valença, Isabelle Guenon, J.-Y. Gillon, Elisabeth Boichot
Publikováno v: British Journal of Pharmacology. 154:1206-1215
Background: Macrophage elastase (MMP-12) is involved in the inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate in mice the effect of MMP-12 inhibition on the inflammatory process induced by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::369adeb0987f17e13d7ac92647a40d9c
https://doi.org/10.1038/bjp.2008.180
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3
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells
Autor: J.-Y. Gillon, Vincent Lagente, Elisabeth Boichot, Isabelle Guenon, Catherine Le Quément
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 294:L1076-L1084
Macrophage metalloelastase (MMP-12) is described to be involved in pulmonary inflammatory response. To determine the mechanisms linking MMP-12 and inflammation, we examined the effect of recombinant human MMP-12 (rhMMP-12) catalytic domain on IL-8/CX
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d3459352cc113ec1ab70586d7eb208
https://doi.org/10.1152/ajplung.00489.2007
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4
Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation
Autor: David Gilot, Vincent Lagente, Valérie Lecureur, Normand Podechard, Olivier Fardel, Eric Le Ferrec, Isabelle Guenon, John R. Gordon, Lydie Sparfel
Publikováno v: Toxicology Letters
Toxicology Letters, 2008, 177 (2), pp.130-7. ⟨10.1016/j.toxlet.2008.01.006⟩
Toxicology Letters, Elsevier, 2008, 177 (2), pp.130-7. ⟨10.1016/j.toxlet.2008.01.006⟩
International audience; Benzo(a)pyrene (BP) is an environmental contaminant known to favor airway inflammation likely through up-regulation of pro-inflammatory cytokines. The present study was designed to characterize its effects toward interleukin-8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9d596df018aad06d6b62dc2993f122
https://doi.org/10.1016/j.toxlet.2008.01.006
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5
Interactions of tachykinin receptor antagonists with lipopolysaccharide-induced airway inflammation in mice
Autor: Soazig Nénan, Vincent Lagente, M Veron, X Emonds-Alt, Elisabeth Boichot, Charles Advenier, Isabelle Guenon
Publikováno v: Clinical and Experimental Pharmacology and Physiology. 31:634-640
1. Several observations suggest that tachykinins are involved in the pathogenesis of bronchopulmonary alterations. We have investigated the effect of antagonists for tachykinin NK1 (SR 140333), NK2 (SR 48968) or NK3 (SR 142801) receptors on inflammat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6f3b4923c7f6d12e7d1116d17e72e0
https://doi.org/10.1111/j.1440-1681.2004.04061.x
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6
A Nitric Oxide-Releasing Salbutamol Elicits Potent Relaxant and Anti-Inflammatory Activities
Autor: Vincent Lagente, Jean-Luc Burgaud, Charles Advenier, Isabelle Guenon, Piero Del Soldato, Marianne Corbel, Elisabeth Boichot, Emmanuel Naline
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 310:367-375
Beta2-adrenoceptor agonists are widely used in the treatment of pulmonary diseases. We have investigated the relaxant and anti-inflammatory activities of NCX-950 (alpha'-[[(1,1-dimethylethy)amino]methyl]-4-hydroxy-1,3-benzenedimethanol nitrate) (a ni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d40b78c69899123d3a80b9d90dc80ae
https://doi.org/10.1124/jpet.103.061739
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8
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
Autor: Elisabeth Boichot, Valérie F. J. Quesniaux, Isabelle Couillin, Emilie Doz, Bernhard Ryffel, Vincent Lagente, Nicolas Noulin, Marc Le Bert, Bruno Schnyder, Isabelle Guenon, Lizette Fick
Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (2), pp.1169-78
Acute cigarette smoke exposure of the airways (two cigarettes twice daily for three days) induces acute inflammation in mice. In this study, we show that airway inflammation is dependent on Toll-like receptor 4 and IL-1R1 signaling. Cigarette smoke i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa475acedeb7b6dedecd5906421ecc80
https://hal.archives-ouvertes.fr/hal-00318566
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9
Anti-inflammatory properties of MMP inhibitors in experimental models of chronic obstructive pulmonary disease and lung inflammation
Autor: Valeria Muzio, J.-Y. Gillon, Catherine Le Quément, Vincent Lagente, Elisabeth Boichot, Isabelle Guenon
Publikováno v: Matrix Metalloproteinases in Tissue Remodelling and Inflammation ISBN: 9783764385842
Matrix metalloproteinases (MMPs) are a group of proteases known to regulate the turnover of extracellular matrix and thus are suggested to be important in the process of lung disease associated with tissue remodelling. Furthermore, the concept that m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a763783fd9a32daabcbfe50e22e148d0
https://doi.org/10.1007/978-3-7643-8585-9_4
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10
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
Autor: Sabine Charron, Vincent Lagente, Caroline Mary, Nicolas Noulin, Shizuo Akira, Isabelle Couillin, Bernhard Ryffel, Valérie F. J. Quesniaux, Silvia Schnyder-Candrian, Isabelle Guenon, Bruno Schnyder, Paméla Gasse
Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2007, 117 (12), pp.3786-99. ⟨10.1172/JCI32285⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2007, 117 (12), pp.3786-99. ⟨10.1172/JCI32285⟩
The molecular mechanisms of acute lung injury resulting in inflammation and fibrosis are not well established. Here we investigate the roles of the IL-1 receptor 1 (IL-1R1) and the common adaptor for Toll/IL-1R signal transduction, MyD88, in this pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82548c22aaf60f1f9401598572679d7f
https://hal.science/hal-00316819
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