Study of hypothalamic leptin receptor expression in low-birth-weight piglets and effects of leptin supplementation on neonatal growth and development

Autor: Jean Djiane, Linda Attig, Isabelle Gourdou, Olivier Rampin, Jean-Yves Madec, Pauline M. Anton, Samir Boukthir, Arieh Gertler, Latifa Abdennebi-Najar, Thibaut Larcher

Publikováno v: AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, American Physiological Society, 2008, 295 (5), pp.E1117-E1125. ⟨10.1152/ajpendo.90542.2008⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2008, pp.E1117-25
American Journal of Physiology. Endocrinology and Metabolism 5 (295), E1117-E1125. (2008)

International audience; Low birth weight resulting from intrauterine growth retardation (IUGR) is a risk factor for further development of metabolic diseases. The pig appears to reproduce nearly all of the phenotypic pathological consequences of huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c724092a60fe8dab2d40974171d61c1d
https://doi.org/10.1152/ajpendo.90542.2008

Effects of prolactin on intracellular calcium concentration and cell proliferation in human glioma cells

Autor: Bruno Sorin, Isabelle Gourdou, Thomas Ducret, Jean Guerin, Pierre Vacher, D. Liguoro, Laurence Bresson-Bepoldin, Sihem Boudina, Anne Marie Vacher

Publikováno v: Glia. 38:200-214

Prolactin (PRL) has several physiological effects on peripheral tissues and the brain. This hormone acts via its membrane receptor (PRL-R) to induce cell differentiation or proliferation. Using reverse transcription-polymerase chain reaction (RT-PCR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3b5bd4666a8bee8f143a8e2682612e
https://doi.org/10.1002/glia.10056

Identification of the hydrophobic strand in the A–B loop of leptin as major binding site III: implications for large-scale preparation of potent recombinant human and ovine leptin antagonists

Autor: Krishnan V. Ramanujan, Eugene E. Gussakovsky, Dana Gonen-Berger, Jean Djiane, Eva Biener, Leonora Niv-Spector, Yackir Benomar, Arieh Gertler, Brian Herman, Isabelle Gourdou, Mohammed Taouis, Isabelle Callebaut

Publikováno v: Biochemical Journal
Biochemical Journal, 2005, 391, pp.221-230. ⟨10.1042/BJ20050457⟩
Biochemical Journal, 2005, 391 (2), pp.221-230. ⟨10.1042/BJ20050457⟩
Biochemical Journal, Portland Press, 2005, 391, pp.221-230. ⟨10.1042/BJ20050457⟩
Biochemical Journal, Portland Press, 2005, 391 (2), pp.221-230. ⟨10.1042/BJ20050457⟩

International audience; Interaction of leptin with its receptors resembles that of interleukin-6 and granulocyte colony-stimulating factor, which interact with their receptors through binding sites I–III. Site III plays a pivotal role in receptors'

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4f254bd19692820414e64e3a2c7558
https://hal.science/hal-00020373

Prolactin stimulates cell proliferation through a long form of prolactin receptor and K+ channel activation

Autor: Halima Ouadid-Ahidouch, Christian Slomianny, Natalia Prevarskaya, Roman Skryma, Etienne Dewailly, Jean Djiane, Philippe Delcourt, Morad Roudbaraki, Brigitte Mauroy, Isabelle Gourdou, Fabien Van Coppenolle, Alexandre Crepin, Sandrine Humez, Jean-Louis Bonnal

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2004, 377, pp.569-578
HAL

PRL (prolactin) has been implicated in the proliferation and differentiation of numerous tissues, including the prostate gland. However, the PRL-R (PRL receptor) signal transduction pathway, leading to the stimulation of cell proliferation, remains u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d9ee24441b7ac3f19046fff8751511
https://hal.inrae.fr/hal-02678006

Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line

Autor: Laurence Pessemesse, Isabelle Gourdou, Karine Laud, J.P. Peyrat, Jean Djiane

Publikováno v: Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2002, 188, pp.219-226

To evaluate whether leptin plays a putative role in breast tumorigenesis, we studied the expression of its long and short receptor isoforms in various tumoral breast tissues. We applied semiquantitative RT-PCR method to RNA extracted from 20 breast c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168714f275943484d25f97263de5edcf
https://pubmed.ncbi.nlm.nih.gov/11911959