Výsledky vyhledávání - "Isabelle Goulet"

Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors

Autor: Eric J. Milliman, Michael C. Yu, Jocelyn Côté, Christopher A. Jackson, Isabelle Goulet, Jennifer A. Vollbracht, Yin-Chu Chen

Publikováno v: Molecular and Cellular Biology. 30:5245-5256

Cotranscriptional recruitment of pre-mRNA splicing factors to their genomic targets facilitates efficient and ordered assembly of a mature messenger ribonucleoprotein particle (mRNP). However, how the cotranscriptional recruitment of splicing factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ba1bb6cfb158324c8f7a76f6f94e8b
https://doi.org/10.1128/mcb.00359-10

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Alternative Splicing Yields Protein Arginine Methyltransferase 1 Isoforms with Distinct Activity, Substrate Specificity, and Subcellular Localization

Autor: Isabelle Goulet, Sophie Boisvenue, Jocelyn Côté, Gabrielle Gauvin

Publikováno v: Journal of Biological Chemistry. 282:33009-33021

PRMT1 is the predominant member of a family of protein arginine methyltransferases (PRMTs) that have been implicated in various cellular processes, including transcription, RNA processing, and signal transduction. It was previously reported that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4b4a2c8e59e86a4e0ecb540a4d0760
https://doi.org/10.1074/jbc.m704349200

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Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells

Autor: Isabelle Goulet, Jocelyn Côté, Geneviève Paris, R. Mitchell Baldwin, Alan Morettin

Protein arginine methylation is catalyzed by protein arginine methyltransferases (PRMTs) and plays an important role in many cellular processes. Aberrant PRMT expression has been observed in several common cancer types; however, their precise contrib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5a93ced89a08c05c0ecbf798bd7dd6
https://europepmc.org/articles/PMC3562305/

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Analyse structurale et architecture de l'inflorescence des Begoniaceae

Autor: Luc Brouillet, Denis Barabé, Isabelle Goulet

Publikováno v: Canadian Journal of Botany. 72:897-914

The inflorescence structure of Begoniaceae was analyzed taking into account their degree of symmetry. Qualitative and quantitative analyses of 71 species led to the recognition of nine architectural models. When the whole plant is considered, the inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50746227119e2e19d08fdb209955866d
https://doi.org/10.1139/b94-115

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Human Dicer C-terminus functions as a 5-lipoxygenase binding domain

Autor: Johanne Doucet, Marija Rakonjac, Andreas Hermansson, Olof Rådmark, Bengt Samuelsson, Patrick Provost, Dominique L. Ouellet, Geneviève Pépin, Vildan Dincbas-Renqvist, Isabelle Goulet, Isabelle Plante

Publikováno v: Biochimica et biophysica acta. 1789(2)

Dicer is a multidomain ribonuclease III enzyme involved in the biogenesis of microRNAs (miRNAs) in the vast majority of eukaryotes. In human, Dicer has been shown to interact with cellular proteins via its N-terminal domain. Here, we demonstrate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f179dfe5f2bbd364ef545dad0408b7
https://pubmed.ncbi.nlm.nih.gov/19022417

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Combined written and oral information prior to gastrointestinal endoscopy compared with oral information alone: a randomized trial

Autor: Gian Dorta, Catherine Rouillard, Jean-Louis Frossard, Isabelle Goulet, Thomas V. Perneger, Antoine Hadengue, Nadereh Azar-Pey, Christian Felley

Publikováno v: BMC Gastroenterology
BMC Gastroenterology, Vol. 8, No 22 (2008)
BMC Gastroenterology, vol. 8, pp. 22
BMC Gastroenterology, Vol 8, Iss 1, p 22 (2008)

Background Little is known about how to most effectively deliver relevant information to patients scheduled for endoscopy. Methods To assess the effects of combined written and oral information, compared with oral information alone on the quality of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0d9c5f8a9cef1cd53d87acb2cf3c7d
https://pubmed.ncbi.nlm.nih.gov/18522729

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Regulation of the Fanconi anemia group C protein through proteolytic modification

Autor: Chantal Godin, Caroline C. Huard, Cedric S. Tremblay, Manuel Buchwald, Isabelle Brodeur, Isabelle Goulet, Edward W. Khandjian, Georges Lévesque, Madeleine Carreau, Marie Chantal Delisle, Chantal Charbonneau

Publikováno v: The Journal of biological chemistry. 279(6)

The function of the Fanconi anemia group C protein (FANCC) is still unknown, though many studies point to a role in damage response signaling. Unlike other known FA proteins, FANCC is mainly localized to the cytoplasm and is thought to act as a messe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f277c733fcafbe4ff494f64217aa67e
https://pubmed.ncbi.nlm.nih.gov/14625294

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Hematopoietic stem cells from fancc(-/-) mice have lower growth and differentiation potential in response to growth factors

Autor: Isabelle Goulet, Michel Aubé, Matthieu Lafrance, Madeleine Carreau, Chantal Charbonneau

Publikováno v: Stem cells (Dayton, Ohio). 20(5)

Fanconi anemia (FA) is a complex recessive genetic disease characterized by progressive bone marrow (BM) failure. We have previously shown that stem cells from the FA group C mouse model have lower long-term primary and secondary reconstitution abili

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https://pubmed.ncbi.nlm.nih.gov/12351814

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Abstract 3789: The alternatively spliced PRMT1 isoform PRMT1v2 promotes breast cancer cell survival and invasiveness

Autor: Jocelyn Côté, Geneviève Paris, Alan Morettin, Isabelle Goulet, Robert Mitchell Baldwin

Publikováno v: Cancer Research. 73:3789-3789

Breast cancer is the leading cause of cancer-related deaths in women. Despite intensive treatment to overcome this disease, recurrence is common and often incurable due to the highly aggressive nature of the recurrent tumour. Protein arginine methyla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4007db35da31e9b191eaa6379e7c8909
https://doi.org/10.1158/1538-7445.am2013-3789

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