Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Isabelle Gloaguen"'
Autor:
Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Antonella Cellucci, Giulio Auciello, Maria Rosaria Battista, Isabelle Gloaguen, Silvia Fortuni, Cristina Cariulo, Vinod Khetarpal, Celia Dominguez, Ignacio Muñoz-Sanjuán, Annalise Di Marco
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7813 (2022)
While blood–brain barrier (BBB) dysfunction has been described in neurological disorders, including Huntington’s disease (HD), it is not known if endothelial cells themselves are functionally compromised when promoting BBB dysfunction. Furthermor
Externí odkaz:
https://doaj.org/article/270c5f78ddb04b92bb989dab36bd3230
Autor:
Annalise Di Marco, Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Maria Rosaria Battista, Antonella Cellucci, Elena Bracacel, Giulio Auciello, Maria Veneziano, Vinod Khetarpal, Mark Rose, Alessandro Rosa, Isabelle Gloaguen, Edith Monteagudo, Todd Herbst, Celia Dominguez, Ignacio Muñoz-Sanjuán
Publikováno v:
Cells, Vol 9, Iss 4, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://doaj.org/article/d4344a862cc142e2914339bfced09308
Autor:
Ivan Fini, Maria Veneziano, Vinod Khetarpal, Elena Bracacel, Todd Herbst, Ignacio Munoz-Sanjuan, Mark Rose, Giulio Auciello, Edith Monteagudo, Alessandro Rosa, Celia Dominguez, Odalys Gonzalez Paz, Antonella Cellucci, Annalise Di Marco, Maria Rosaria Battista, Isabelle Gloaguen, Domenico Vignone
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 994, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a041cf35a29cb7bd1fddf8e63e91991e
http://hdl.handle.net/11573/1387940
http://hdl.handle.net/11573/1387940
Autor:
Mauro M. Teixeira, Juan Carlos Cutrin, Riccardo Bertini, Emanuela Galliera, Giuseppe Nano, Maria Candida Cesta, B Cavalieri, C. Di Giacinto, P. Di Benedetto, Marcello Allegretti, Andrea R. Beccari, Remo Castro Russo, Andrea Aramini, Lucíola S. Barcelos, Massimo Locati, Isabelle Gloaguen, Alessio Moriconi, Massimiliano M. Corsi, Silvia Passos Andrade, Cinzia Bizzarri
Publikováno v:
British Journal of Pharmacology. 165:436-454
BACKGROUND AND PURPOSE DF 2156A is a new dual inhibitor of IL-8 receptors CXCR1 and CXCR2 with an optimal pharmacokinetic profile. We characterized its binding mode, molecular mechanism of action and selectivity, and evaluated its therapeutic potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49490486cd39d0ddd9d5359b2a037a1
https://doi.org/10.1111/j.1476-5381.2011.01566.x
https://doi.org/10.1111/j.1476-5381.2011.01566.x
Autor:
Francesco Colotta, Claudio Festuccia, Andrea Bianchini, B Cavalieri, Isabelle Gloaguen, Elisabetta Ferretti, Maria Neve Cervellera, Cinzia Bizzarri, Raffaele Strippoli, Fabrizio Mainiero, Federica Casilli, Riccardo Bertini, Edoardo Alesse, Rosa Di Bitondo, Leda Biordi
Publikováno v:
Biochemical Pharmacology. 69:385-394
Repertaxin is a new non-competitive allosteric blocker of interleukin-8 (CXCL8/IL-8) receptors (CXCR1/R2), which by locking CXCR1/R2 in an inactive conformation prevents receptor signaling and human polymorphonuclear leukocyte (PMN) chemotaxis. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649d05945f52c7a264b6157f7eef4527
https://doi.org/10.1016/j.bcp.2004.10.007
https://doi.org/10.1016/j.bcp.2004.10.007
Autor:
Giulia Troiani, Francesco Colotta, Vito Di Cioccio, Elisa Margherita Cattozzo, Isabelle Gloaguen, Fabrizio Mainiero, Riccardo Bertini, Maria Neve Cervellera, Raffaele Strippoli, Sabrina Pagliei, Cinzia Bizzarri, Angela Santoni, Antonella Colagrande
Publikováno v:
Immunology. 111:407-415
The signalling pathways leading to CXCL8/IL-8-induced human neutrophil migration have not been fully characterized. The present study demonstrates that CXCL8 induces tyrosine phosphorylation as well as enzymatic activity of proline-rich tyrosine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b998142da8e84cf35f3be01c50e8020a
https://doi.org/10.1111/j.1365-2567.2004.01822.x
https://doi.org/10.1111/j.1365-2567.2004.01822.x
Autor:
Isabelle Gloaguen, J Garcia, G.A Hauptman, K.L. Neitzel, Nancy Lee, B.K. Devlin, A.J. MacLennan, A. Di Marco, Ralph Laufer
Publikováno v:
Neuroscience. 99:761-772
The ciliary neurotrophic factor receptor is critically involved in embryonic motor neuron development. Postnatally, it may contribute to neuronal maintenance and regeneration. In addition, pharmacological stimulation of the receptor may slow the prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52381eb98c2a941f527d4b8023768bd
https://doi.org/10.1016/s0306-4522(00)90236-7
https://doi.org/10.1016/s0306-4522(00)90236-7
Autor:
Isabelle Gloaguen, Domenico Lazzaro, Gennaro Ciliberto, Annalise Di Marco, Anna Demartis, Ralph Laufer, Paola Delmastro
Publikováno v:
European Journal of Biochemistry. 267:2939-2944
Leptin is an adipocyte-secreted hormone that regulates body weight and exerts effects on hematopoiesis, reproduction, and immunity. The leptin receptor (OBR) shares sequence similarity and signaling capabilities with receptors for cytokines of the ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e7a0842a39ee1b86f4d34f2a36fd1fc
https://doi.org/10.1046/j.1432-1033.2000.01308.x
https://doi.org/10.1046/j.1432-1033.2000.01308.x
Autor:
Rosa Di Bitondo, Claudia Di Giacinto, Maria Candida Cesta, Cinzia Bizzarri, Riccardo Bertini, Manolo R. Sablone, Andrea Aramini, Marcello Allegretti, Massimiliano Aschi, Marcello Crucianelli, Alessio Moriconi, Isabelle Gloaguen
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(15)
We reported recently the Structure-Activity Relationship (SAR) of a class of CXCL8 allosteric modulators. They invariably share a 2-arylpropionic moiety so far considered a key structural determinant of the biological activity. We show the results of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84cd553bbb9dbdaff84112bf97bb3ae
https://pubmed.ncbi.nlm.nih.gov/19560921
https://pubmed.ncbi.nlm.nih.gov/19560921