Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Isabelle Gillaizeau"'
Autor:
Oleh O. Lukianov, Viktor M. Tkachuk, Diana S. Stepanova, Isabelle Gillaizeau, Volodymyr A. Sukach
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 21, Iss 4, Pp 18-26 (2023)
Poly(ADP-ribose) polymerases (PARPs) are key enzymes in the DNA repair pathway. Inhibitors of these enzymes belong to a new type of anticancer drugs that selectively kill cancer cells by targeting the homologous recombination genetic defects. This st
Externí odkaz:
https://doaj.org/article/d13eb6547a064584af8a36d504abe150
Publikováno v:
Molecules, Vol 29, Iss 12, p 2884 (2024)
This review collects the synthetic modifications performed on andrographolide, a natural molecule derived from Andrographis paniculata, for oncology applications. Various pharmacomodulations were carried out, and the products were tested on different
Externí odkaz:
https://doaj.org/article/617171e7aa5045289a94531ab6c59bac
Publikováno v:
Molbank, Vol 2022, Iss 2, p M1382 (2022)
The synthesis and crystallization of 2,3,5-tri-O-benzyl-d-xylofuranose permitted us to isolate the alpha anomer with a small contamination of the beta form (ca 10%), whose first crystallographic structure obtained in the P212121 space group was deter
Externí odkaz:
https://doaj.org/article/72f36923f4124b2e84466ae221912162
Autor:
Viktor M. Tkachuk, Oleh O. Lukianov, Mykhailo V. Vovk, Isabelle Gillaizeau, Volodymyr A. Sukach
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 2304-2313 (2020)
The Chan–Evans–Lam reaction of 1-unsubstituted 4-fluoroalkylpyrimidin-2(1Н)-ones with arylboronic acids is reported as a facile synthetic route to hitherto unavailable N1-(het)aryl and N1-alkenyl derivatives of the corresponding pyrimidines. An
Externí odkaz:
https://doaj.org/article/9e616f0d2a0048b6bbad5125f0c25190
Publikováno v:
Advanced Synthesis and Catalysis
Advanced Synthesis and Catalysis, 2023, Advanced Synthesis & Catalysis, 365, pp.156-160. ⟨10.1002/adsc.202201147⟩
Advanced Synthesis and Catalysis, 2023, Advanced Synthesis & Catalysis, 365, pp.156-160. ⟨10.1002/adsc.202201147⟩
International audience; Although the metal-based catalyzed cyanomethylation of aldehydes is well-developed, a similar approach to ketones with acetonitrile derivatives remains a challenge. Thanks to Tolman type complexes, NiIIcomplexes with a pyridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366bfbd663255f79b502630c8443f20b
https://doi.org/10.1002/adsc.202201147
https://doi.org/10.1002/adsc.202201147
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2021, 19 (30), pp.6623-6627. ⟨10.1039/D1OB01075A⟩
Organic & Biomolecular Chemistry, 2021, 19 (30), pp.6623-6627. ⟨10.1039/D1OB01075A⟩
International audience; Isocoumarins are important building blocks in medicinal chemistry. An access to 3-amino-4-halo- or 4-seleno-isocoumarins in a short time (\textless1 min) with good yields was reported via an electrophilic cyclization of ortho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa9f5e0b2293cb8f9678ff04e7cbc69
https://doi.org/10.1039/d1ob01075a
https://doi.org/10.1039/d1ob01075a
Publikováno v:
RSC Advances. 10:9934-9939
A simple and original efficient synthesis of 3-amino-1H-isochromene bearing a bromine atom at the C-1 position via a 6-endo-cyclization approach from in situ generated ortho-ynamidyl het(aryl) aldehyde derivatives is achieved under mild reaction cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cb947b8f342c0c90af47fe811fc744
https://doi.org/10.1039/d0ra00768d
https://doi.org/10.1039/d0ra00768d
Autor:
Damla Torun, Isabelle Gillaizeau
Publikováno v:
Comprehensive Heterocyclic Chemistry IV
David StC Black; Janine Cossy; Christian V. Stevens. Comprehensive Heterocyclic Chemistry IV, 13, Elsevier, pp.550-564, 2022, Seven-membered Heterocyclic Rings and their Fused Derivatives, directed by Floris P.J.T Rutjes, 978-0-12-818656-5. ⟨10.1016/B978-0-12-818655-8.00133-5⟩
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
David StC Black; Janine Cossy; Christian V. Stevens. Comprehensive Heterocyclic Chemistry IV, 13, Elsevier, pp.550-564, 2022, Seven-membered Heterocyclic Rings and their Fused Derivatives, directed by Floris P.J.T Rutjes, 978-0-12-818656-5. ⟨10.1016/B978-0-12-818655-8.00133-5⟩
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
International audience; The content of this study dedicated to seven-membered heterocycles containing 1,3,5 heteroatoms is organized according to the type of 1,3,5 triheteropine ring system and the selected studies published since 2008. New synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2e569230a2ee3d544d2ca653b8bd7c
https://univ-orleans.hal.science/hal-03658731
https://univ-orleans.hal.science/hal-03658731
Publikováno v:
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering ISBN: 9780124095472
Comprehensive Chirality
Cossy, Janine. Comprehensive Chirality, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2022, ⟨10.1016/B978-0-32-390644-9.00043-3⟩
Comprehensive Chirality
Cossy, Janine. Comprehensive Chirality, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2022, ⟨10.1016/B978-0-32-390644-9.00043-3⟩
International audience; Asymmetric hydrochalcogenylation of olefins, including hydrophosphination, hydrosulfenylation and hydroselenation, has emerged as a powerful approach for constructing chiral compounds in an enantioselective manner by generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49de66dc833bb9877591cf0f466315c
https://doi.org/10.1016/b978-0-32-390644-9.00043-3
https://doi.org/10.1016/b978-0-32-390644-9.00043-3
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2019, 21, pp.5621-5625. ⟨10.1021/acs.orglett.9b01963⟩
Organic Letters, American Chemical Society, 2019, 21, pp.5621-5625. ⟨10.1021/acs.orglett.9b01963⟩
This work reports a simple and efficient method for the direct phosphorylation of enamide under metal-free conditions. The P-centered radicals, derived from secondary phosphine oxides, are generated under mild reaction conditions in the presence of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611e2b22a0ad05f4f6d1f6f2a38d979c
https://doi.org/10.1021/acs.orglett.9b01963
https://doi.org/10.1021/acs.orglett.9b01963