Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Isabelle Gennero"'
Autor:
Fabienne Briand-Mésange, Isabelle Gennero, Juliette Salles, Stéphanie Trudel, Lionel Dahan, Jérôme Ausseil, Bernard Payrastre, Jean-Pierre Salles, Hugues Chap
Publikováno v:
Molecules, Vol 29, Iss 15, p 3694 (2024)
2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the sequential action of phosphoinositide-speci
Externí odkaz:
https://doaj.org/article/9abc783c17c548a88592a6d84b2648a0
Autor:
Nissrine Ballout, Agnès Boullier, Walaa Darwiche, Katia Ait-Mohand, Eric Trécherel, Théo Gallégo, Cathy Gomila, Linda Yaker, Isabelle Gennero, José Kovensky, Jérôme Ausseil, Sylvestre Toumieux
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1512 (2023)
Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony callus formation, and bone remodelling. Bone fractures represent a significant health problem, p
Externí odkaz:
https://doaj.org/article/d6163f796d494d689c2dc1e66048285e
Autor:
Dibia Liz Pacoricona Alfaro, Gwenaelle Diene, Graziella Pinto, Jean-Pierre Salles, Isabelle Gennero, Sandy Faye, Catherine Molinas, Marion Valette, Catherine Arnaud, Maithé Tauber
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Adolescents with idiopathic scoliosis display high ghrelin levels. As hyperghrelinemia is found in patients with PWS and early-onset scoliosis (EOS) is highly prevalent in these patients, our aims were to explore (1) whether ghrel
Externí odkaz:
https://doaj.org/article/85c4c50f7a6a445abadf58f6047bda63
Autor:
Coline Rouleau, Margaux Malorie, Corinne Collet, Valérie Porquet-Bordes, Isabelle Gennero, Sanaa Eddiry, Michel Laroche, Jean Pierre Salles, Guillaume Couture, Thomas Edouard
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101176- (2022)
Aim: To describe the presenting features, bone characteristics and molecular genetics in a large monocentric cohort of children and young adults with idiopathic primary osteoporosis. Methods: Sixty-six patients (19 children, 47 adults; 28 males, 38 f
Externí odkaz:
https://doaj.org/article/da53931ce1f04fc39360489f39780b7d
Autor:
Ronan Barre, Nicolas Beton, Aurélie Batut, Frank Accabled, Jerome Sales de Gauzy, Françoise Auriol, Sanaa Eddiry, Maithe Tauber, Sara Laurencin, Jean Pierre Salles, Isabelle Gennero
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100782- (2020)
We have examined the Acylated Ghrelin (AG)/Gi pathway in different human osteoblastic cell lines. We have found that: 1) AG induces differentiation/mineralization only in mature osteoblasts; 2) the expression of GHS-R1a increases up to the mature cel
Externí odkaz:
https://doaj.org/article/6ea7d449ef3444328547430fe9d5b148
Autor:
Adebayo Candide Alioli, Léa Demesmay, Sara Laurencin, Nicolas Beton, Delphine Farlay, Helene Follet, Jerold Chun, Richard Rivera, Daniel Bouvard, Irma Machuca-Gayet, Jean-Pierre Salles, Isabelle Gennero, Olivier Peyruchaud
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100432- (2020)
Externí odkaz:
https://doaj.org/article/7126ce322d924a1f94babb6264e32888
Autor:
Fati Nourhashemi, Claudie Hooper, Christelle Cantet, Catherine Féart, Isabelle Gennero, Pierre Payoux, Anne Sophie Salabert, Sophie Guyonnet, Philipe De Souto Barreto, Bruno Vellas, for the Multidomain Alzheimer Preventive Trial/Data sharing Alzheimer (DSA) study group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-7 (2018)
Abstract Background Vitamin D deficiency is associated with an increased risk of Alzheimer’s disease and increased beta-amyloid (Aβ) in animals. Hence we sought to investigate the relationship between plasma 25-hydroxyvitamin D (25(OH)D) and cereb
Externí odkaz:
https://doaj.org/article/bc9d21ba350b45ba80af6367e81f5282
HIV-1-Infected Human Macrophages, by Secreting RANK-L, Contribute to Enhanced Osteoclast Recruitment
Autor:
Rémi Mascarau, Florent Bertrand, Arnaud Labrousse, Isabelle Gennero, Renaud Poincloux, Isabelle Maridonneau-Parini, Brigitte Raynaud-Messina, Christel Vérollet
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3154 (2020)
HIV-1 infection is frequently associated with low bone density, which can progress to osteoporosis leading to a high risk of fractures. Only a few mechanisms have been proposed to explain the enhanced osteolysis in the context of HIV-1 infection. As
Externí odkaz:
https://doaj.org/article/7efe14c2875747be8461243a0e306b01
Autor:
Celine Saint-Laurent, Stephanie Garcia, Vincent Sarrazy, Karine Dumas, Florence Authier, Sophie Sore, Albert Tran, Philippe Gual, Isabelle Gennero, Jean-Pierre Salles, Elvire Gouze
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195876 (2018)
Achondroplasia is a rare genetic disease is characterized by abnormal bone development and early obesity. While the bone aspect of the disease has been thoroughly studied, early obesity affecting approximately 50% of them during childhood has been so
Externí odkaz:
https://doaj.org/article/35dc66f3290840868b6ce19b5ac9a2cd
Autor:
Lisa Cole Burnett, Françoise Conte Auriol, Eric Bieth, Jean Pierre Salles, Juliette Salles, Maithé Tauber, Gwenaelle Diene, Catherine Molinas, Rudolph L. Leibel, Boris V. Skryabin, Isabelle Gennero, Timofey S. Rozhdestvensky, Sanaa Eddiry
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
International audience; Purpose: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the 15q11-q13 chromosome. Among them, the SNORD116 gene appears critical for t