Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Isabelle Gagnon-Arsenault"'
Autor:
Francois D Rouleau, Alexandre K Dubé, Isabelle Gagnon-Arsenault, Soham Dibyachintan, Alicia Pageau, Philippe C Després, Patrick Lagüe, Christian R Landry
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011252 (2024)
Pneumocystis jirovecii is a fungal pathogen that causes pneumocystis pneumonia, a disease that mainly affects immunocompromised individuals. This fungus has historically been hard to study because of our inability to grow it in vitro. One of the main
Externí odkaz:
https://doaj.org/article/02de62579ea74a79aa374817d42790d2
Autor:
Axelle Marchant, Angel F Cisneros, Alexandre K Dubé, Isabelle Gagnon-Arsenault, Diana Ascencio, Honey Jain, Simon Aubé, Chris Eberlein, Daniel Evans-Yamamoto, Nozomu Yachie, Christian R Landry
Publikováno v:
eLife, Vol 8 (2019)
Gene duplication is a driver of the evolution of new functions. The duplication of genes encoding homomeric proteins leads to the formation of homomers and heteromers of paralogs, creating new complexes after a single duplication event. The loss of t
Externí odkaz:
https://doaj.org/article/6b83d7141d3b43048d05a6d3e0b5f734
Autor:
Clara Bleuven, Alexandre K. Dubé, Guillaume Q. Nguyen, Isabelle Gagnon‐Arsenault, Hélène Martin, Christian R. Landry
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)
Abstract While the use of barcoded collections of laboratory microorganisms and the development of barcode‐based cell tracking are rapidly developing in genetics and genomics research, tools to track natural populations are still lacking. The yeast
Externí odkaz:
https://doaj.org/article/e8d97ada188f4461bf76760a741acd3a
Autor:
Sondos Samandi, Annie V Roy, Vivian Delcourt, Jean-François Lucier, Jules Gagnon, Maxime C Beaudoin, Benoît Vanderperre, Marc-André Breton, Julie Motard, Jean-François Jacques, Mylène Brunelle, Isabelle Gagnon-Arsenault, Isabelle Fournier, Aida Ouangraoua, Darel J Hunting, Alan A Cohen, Christian R Landry, Michelle S Scott, Xavier Roucou
Publikováno v:
eLife, Vol 6 (2017)
Recent functional, proteomic and ribosome profiling studies in eukaryotes have concurrently demonstrated the translation of alternative open-reading frames (altORFs) in addition to annotated protein coding sequences (CDSs). We show that a large numbe
Externí odkaz:
https://doaj.org/article/6aa1a82d2e824bd38587ba83dbdc8a9e
Autor:
Guillaume Diss, Alexandre K. Dubé, Joël Boutin, Isabelle Gagnon-Arsenault, Christian R. Landry
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 2155-2167 (2013)
Cells contain many important protein complexes involved in performing and regulating structural, metabolic, and signaling functions. One major challenge in cell biology is to elucidate the organization and mechanisms of robustness of these complexes
Externí odkaz:
https://doaj.org/article/a669d60dc6ed41779e035d334e874134
Autor:
Marie Filteau, Véronique Hamel, Marie‐Christine Pouliot, Isabelle Gagnon‐Arsenault, Alexandre K Dubé, Christian R Landry
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 10, Pp n/a-n/a (2015)
Abstract Since deleterious mutations may be rescued by secondary mutations during evolution, compensatory evolution could identify genetic solutions leading to therapeutic targets. Here, we tested this hypothesis and examined whether these solutions
Externí odkaz:
https://doaj.org/article/c18131d7ad994c36ad914cf2bdbf9379
Autor:
Alex N Nguyen Ba, Bob Strome, Jun Jie Hua, Jonathan Desmond, Isabelle Gagnon-Arsenault, Eric L Weiss, Christian R Landry, Alan M Moses
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 12, p e1003977 (2014)
Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization. Consistent with functional divergence after gene duplication, recent studies have show
Externí odkaz:
https://doaj.org/article/2f338d7e117f41aab6126831fffdba34
Autor:
Jean-Baptiste Leducq, Guillaume Charron, Guillaume Diss, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Christian R Landry
Publikováno v:
PLoS Genetics, Vol 8, Iss 12, p e1003161 (2012)
Despite the tremendous efforts devoted to the identification of genetic incompatibilities underlying hybrid sterility and inviability, little is known about the effect of inter-species hybridization at the protein interactome level. Here, we develop
Externí odkaz:
https://doaj.org/article/08967337d9d6415987d5a401d4156093
Autor:
Damien Biot-Pelletier, Stefano Bettinazzi, Isabelle Gagnon-Arsenault, Alexandre K Dubé, Camille Bédard, Tuc H M Nguyen, Heather L Fiumera, Sophie Breton, Christian R Landry
Critical mitochondrial functions, including cellular respiration, rely on frequently interacting components expressed from both the mitochondrial and nuclear genomes. The fitness of eukaryotic organisms depends on a tight collaboration between both g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9bd48c833bdf87e671b526e81fa7e4
https://doi.org/10.1101/2022.09.11.507487
https://doi.org/10.1101/2022.09.11.507487
Autor:
Christian R. Landry, Isabelle Gagnon-Arsenault, Diana Ascencio, Alexander DeLuna, Guillaume Diss, Alexandre K. Dubé
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Many studies have focused on the mechanisms of long-term retention of gene duplicates, such as the gain of functions or reciprocal losses. However, such changes are more likely to occur if the duplicates are maintained for a long period.